Sentences with phrase «as a tumor suppressing»

HDACs are a family of enzymes which, amongst other things, influence access to DNA and are involved in whether specific genes, such as tumor suppressing genes, are expressed or not.

Not exact matches

Teixeira and his team also found that a malfunctioning tumor - suppressing gene that's associated with certain cancers, such as colon and pancreatic, and is known as Stk11, additionally influenced the development of BPH.

If the silencing occurred in a gene responsible for suppressing tumor formation, the result would appear the same as genetic mutations that predispose people to cancer.

A tumor - suppressing protein acts as a dimmer switch to dial down gene expression.

«These findings reveal a unique fulvestrant signaling process involving the increased regulation of hsa - miR - 765 that suppresses the HMGA1 protein as part of the mechanism underlying the tumor suppressor action in prostate cancer.

«We searched for genes that are occasionally deleted in some cancers but which are retained in cancers caused by specific tumor suppressing genes, such as PTEN,» said Di Zhao, Ph.D., Odyssey postdoctoral fellow in Cancer Biology and first author on the Nature paper.

Beyond identifying the Sestrin1 gene as frequently altered in FL patients, the scientists demonstrated that Sestrin1 is able to suppress tumors in vivo.

In humans, cancer develops when genes that suppress cancer, known as tumor suppressors, are lost and when mutations or genes that promote cancer, known as oncogenes, are gained or activated.

When there is a mutation in one or both of the PTEN genes, it interferes with the protein's enzymatic activity and, as a result inhibits its tumor suppressing ability.

But as malignant cells multiply and form tumors, they release biochemical signals that suppress the immune system and the T - cells no longer function properly.

As a result, they can more efficiently interact with the cell membrane, regulate cell growth and suppress tumor formation.

Because the proteins can be engineered to suppress tumor growth they have emerged as a potential cancer therapy.

Teixeira and his team also found that a malfunctioning tumor - suppressing gene that's associated with certain cancers, such as colon and pancreatic, known as Stk11, additionally influenced the development of BPH.

They found that as women age, the cells responsible for maintaining healthy breast tissue stop responding to their immediate surroundings, including mechanical cues that should prompt them to suppress nearby tumors.

Paul Ehrlich proposes that the immune system usually suppresses tumor formation, a concept that becomes known as the «immune surveillance» hypothesis.

Researchers led by St. Jude Children's Research Hospital scientists have worked out how a crucial cancer - related protein, a «histone writer» called Ezh2, plays a role in suppressing as well as driving the most aggressive form of the brain tumor medulloblastoma.

However, for people who do not have a tumor, or in specific cases, medications such as somatostatin analogues or dopamine agonists that suppress growth hormone secretion may be used.

They found that tumor growth was suppressed more than 50 percent as compared to the control mice without the shot.

Amy's own childhood, as the descendant of a famous doctor herself, was fraught with dysfunction that led her to suppress the distress of the first 18 years of her life that finally exploded as a cancerous tumor wedged between her heart and lung and an autoimmune disease that caused critical issues with her treatment.

This can be a hormone imbalance such as an overly active adrenal gland, diabetes, liver or kidney failure, an immunosuppressive tumor or the use of medications that suppress your pet's ability to keep mite numbers under control.

Tea has been scientifically associated with health benefits such as suppressing tumor progression and decreasing inflammation.