Not exact matches
She found that milestone achievement was
abnormal in these monkeys: at six to eight weeks they were slow in starting to manipulate, and at ten months the increase in «motor disturbance behaviors» that normally occurs was prolonged.101 The author concludes, «These effects could occur
as a result of effects on vulnerable
brain processes during a sensitive period, interference with programming of [normal]
brain development by endogenous [internal] agents or alteration in early experiences.»
These changes affect normal
brain processes, such
as development or memory, and
abnormal brain processes, such
as depression, drug dependence, and other psychiatric disease — and can pass down to subsequent generations.
Lahn and his colleagues looked at the
abnormal spindle - like microcephaly associated (ASPM) gene, which scientists had previously identified
as a key player in
brain development.
«Some neuropsychiatric disorders, such
as schizophrenia and autism, are characterized by the
abnormal development of synaptic connectivity in certain key parts of the
brain,» explains Schneggenburger.
This leads to
abnormal brain development and a small head circumference
as well
as dysfunction of peripheral nerves.
The discovery may help explain why humans evolved more elaborate
brains than mice, and it could suggest ways to treat disorders such
as autism and epilepsy that arise from
abnormal neural
development.
Scientists have identified a basic pathologic process underlying Alzheimer's
development that involves the formation of
abnormal protein deposits in the
brain known
as beta - amyloid plaques, but they still aren't entirely sure what causes this to happen.