While no other risk factors were observed for the development of ADHD - only, more deviant peer affiliations and lower SES did act
as additional risk factors for ADHD + ODD, compared with controls.
The reconciliation is that we are considering homebirth so long
as no additional risk factors pop up.
70 % is extreme — in USA only one state (Alaska) has the majority of bedsharing deaths happening with drugs or alcohol
as additional risk factor present (large minority population where that is prevalent too).
Professor Peymané Adab, Professor of Chronic Disease Epidemiology & Public Health, said: «This study contributes to existing evidence for sleep duration as a risk factor for obesity in childhood, and later bedtime
as an additional risk factor — regardless of sleep duration.
15 In fact, type 2 diabetes (T2D)-- a condition stemming from broken glucose metabolism and insulin signaling — has been identified
as an additional risk factor for developing AD.16, 17 Moreover, the pathological changes that occur in AD in the brain physically resemble those seen in the pancreas and vasculature in T2D.9, 18 Type 2 diabetics who carry ApoE4 alleles are at the greatest risk for AD, with an even more severe risk reserved for those treated with exogenous insulin.19 This suggests that either T2D or related features of the metabolic syndrome bring about AD, or that they are separate consequences of the same underlying cause — and moreover, that insulin is a key factor.
Not exact matches
Important
factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for
additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals
as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such
as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with
additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the
risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow
additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such
as U.S. export control laws and U.S. and foreign anti-bribery laws such
as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such
as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers,
as well
as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our
additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco
as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the
risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
Certain matters discussed in this news release are forward - looking statements that involve a number of
risks and uncertainties including, but not limited to, doubts about the Company's ability to continue
as a going concern, the need to obtain
additional funding,
risks in product development plans and schedules, rapid technological change, changes and delays in product approval and introduction, customer acceptance of new products, the impact of competitive products and pricing, market acceptance, the lengthy sales cycle, proprietary rights of the Company and its competitors,
risk of operations in Israel, government regulations, dependence on third parties to manufacture products, general economic conditions and other
risk factors detailed in the Company's filings with the United States Securities and Exchange Commission.
Actual results, including with respect to our targets and prospects, could differ materially due to a number of
factors, including the
risk that we may not obtain sufficient orders to achieve our targeted revenues; price competition in key markets; the
risk that we or our channel partners are not able to develop and expand customer bases and accurately anticipate demand from end customers, which can result in increased inventory and reduced orders
as we experience wide fluctuations in supply and demand; the
risk that our commercial Lighting Products results will continue to suffer if new issues arise regarding issues related to product quality for this business; the
risk that we may experience production difficulties that preclude us from shipping sufficient quantities to meet customer orders or that result in higher production costs and lower margins; our ability to lower costs; the
risk that our results will suffer if we are unable to balance fluctuations in customer demand and capacity, including bringing on
additional capacity on a timely basis to meet customer demand; the
risk that longer manufacturing lead times may cause customers to fulfill their orders with a competitor's products instead; the
risk that the economic and political uncertainty caused by the proposed tariffs by the United States on Chinese goods, and any corresponding Chinese tariffs in response, may negatively impact demand for our products; product mix;
risks associated with the ramp - up of production of our new products, and our entry into new business channels different from those in which we have historically operated; the
risk that customers do not maintain their favorable perception of our brand and products, resulting in lower demand for our products; the
risk that our products fail to perform or fail to meet customer requirements or expectations, resulting in significant
additional costs, including costs associated with warranty returns or the potential recall of our products; ongoing uncertainty in global economic conditions, infrastructure development or customer demand that could negatively affect product demand, collectability of receivables and other related matters
as consumers and businesses may defer purchases or payments, or default on payments;
risks resulting from the concentration of our business among few customers, including the
risk that customers may reduce or cancel orders or fail to honor purchase commitments; the
risk that we are not able to enter into acceptable contractual arrangements with the significant customers of the acquired Infineon RF Power business or otherwise not fully realize anticipated benefits of the transaction; the
risk that retail customers may alter promotional pricing, increase promotion of a competitor's products over our products or reduce their inventory levels, all of which could negatively affect product demand; the
risk that our investments may experience periods of significant stock price volatility causing us to recognize fair value losses on our investment; the
risk posed by managing an increasingly complex supply chain that has the ability to supply a sufficient quantity of raw materials, subsystems and finished products with the required specifications and quality; the
risk we may be required to record a significant charge to earnings if our goodwill or amortizable assets become impaired;
risks relating to confidential information theft or misuse, including through cyber-attacks or cyber intrusion; our ability to complete development and commercialization of products under development, such
as our pipeline of Wolfspeed products, improved LED chips, LED components, and LED lighting products
risks related to our multi-year warranty periods for LED lighting products;
risks associated with acquisitions, divestitures, joint ventures or investments generally; the rapid development of new technology and competing products that may impair demand or render our products obsolete; the potential lack of customer acceptance for our products;
risks associated with ongoing litigation; and other
factors discussed in our filings with the Securities and Exchange Commission (SEC), including our report on Form 10 - K for the fiscal year ended June 25, 2017, and subsequent reports filed with the SEC.
Examples of these
risks, uncertainties and other
factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Comm
factors include, but are not limited to the impact of: adverse general economic and related
factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Comm
factors, such
as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such
as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the
risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise
additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged
as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit
risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other
factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Comm
factors set forth under «
Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Comm
Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.
As long as you pay attention to the information in the section above regarding additional risk factors and stay away from those potential problems, the worst that can happen is that you may develop an infection from your tattoo and require antibiotics to clear it u
As long
as you pay attention to the information in the section above regarding additional risk factors and stay away from those potential problems, the worst that can happen is that you may develop an infection from your tattoo and require antibiotics to clear it u
as you pay attention to the information in the section above regarding
additional risk factors and stay away from those potential problems, the worst that can happen is that you may develop an infection from your tattoo and require antibiotics to clear it up.
While it has yet to make the official list, some studies have identified VOCs and
additional indoor air pollutants
as a
risk factor for SIDS.
Data on
additional risk factors or possible confounders, such
as maternal age, parity, gestational age, ethnicity, and socioeconomic status, were collected from records accumulated during the pregnancy outcome study.
Healthcare providers may screen a child more frequently if there are
additional risk factors, such
as preterm birth, low birthweight, and lead exposure, among others.
Additional evidence from studies which have looked at other aspects of social support such
as the level of received support or sources of social support also provided evidence to support the hypothesis that the level of social support is an important
factor in postpartum depression and that if social support is absent then it can be a potential
risk factor for postpartum depression.
The agency has a good understanding of some
risk factors for teen dating violence, such
as family background, she said, and it is now studying the relationship between teen partners to see what
additional risk factors can be found.
Additional research is needed to determine how questions about peak alcohol consumption levels can be valuable in screening for alcohol misuse,
as well
as in assessing gender - specific
risk factors and harms for drinking at extreme levels.
«More research is needed in Canada on
additional contributing
risk factors as well
as longitudinal data to evaluate the complex relationship between e-cigarette use and tobacco cigarette use in adolescence.»
«GECCO aims to continue to discover
additional colorectal cancer - related variants by investigating how genetic variants are modified by other environmental and lifestyle
risk factors, including biomarkers
as well
as how they influence patient treatment response and survival,» Peters said, emphasizing how much further research is required to uncover the specific mechanisms by which genes modulate the intake of certain foods on colorectal cancer
risk.
«Further, the
additional assessment of NAFLD with CT could improve the
risk stratification of patients with suspected coronary artery disease,
as our results show that the presence of NAFLD is associated with high -
risk coronary plaque independent of traditional
risk factors and severity of coronary artery disease.»
Larsen said
additional research is needed to determine why diabetes carries a greater
risk than other traditional
risk factors, such
as high blood pressure, in this group.
«Studies that aim to predict the consequences of climate change on insect populations should consider
additional factors that may ultimately limit growth and survival, such
as the
risk of being eaten by a predator,» Culler says.
Individuals with such disorders may also experience
additional risk factors, such
as the easy availability of tobacco in some treatment centers.
Samuels said
additional studies are needed to gauge the impact of adolescent obesity on other cardiovascular
risk factors such
as diabetes and obstructive sleep apnea.
The United Kingdom - based group, led by Julie Williams, Ph.D., Cardiff University School of Medicine, Wales, found the same genes
as risk factors and identified a gene variant ABCA7
as an
additional gene of interest.
In 2009 and 2010, however, researchers confirmed
additional gene variants of CR1, CLU and PICALM
as possible
risk factors for late - onset Alzheimer's.
This genetic
risk factor is independent of other
risk factors, such
as cholesterol, obesity and smoking, and therefore provides an
additional method for identifying individuals who may derive benefit from earlier and more aggressive prevention efforts.
After adjusting for common
factors that influence breast cancer
risk, Henderson and colleagues found that women whose mammograms were classified
as false - positive who were referred for
additional imaging had a 39 percent increased chance of developing subsequent breast cancer during the 10 - year follow - up period, compared with women with a true - negative result.
For consumption, we used the midpoint of the reported number of cigarettes per day — for example, three cigarettes per day if the category was one to five cigarettes per day — which we then adjusted for carboxyhaemoglobin and cotinine because this allows for lower inhalation with increasing cigarette consumption
as previously established.14 For studies that reported relative
risks adjusted for age (or for
additional factors), the model contained the logarithm of the relative
risk (dependent variable) and consumption (independent variable) using only the midpoint of the cigarettes per day categories.
Additional factors such
as dark skin, low HDL cholesterol («good cholesterol»), low dairy consumption, and obesity also increase the
risk of vitamin D deficiency.
Not only was regular bean consumption
as effective
as portion control in reducing prediabetes
risk factors like slimming waistlines and better blood sugar control, but the bean diet led to
additional benefits beyond just calorie reduction, presumably due to some functional properties of the beans and peas.
Additionally, each 3.5 - ounce (100 - gram) decrease in weekly fish consumption was associated with a 19 % higher likelihood of having one
additional risk factor for heart disease, such
as high blood pressure, diabetes or obesity (22).
The researchers said finding a higher
risk of diabetes even after adjusting for lifestyle
factors and weight status suggests that
additional factors, such
as disruption of the circadian rhythm, may play a role.
What you can do: Get your blood glucose levels tested once or twice a year; if you have
additional risk factors, such
as being overweight, ask your doc if you should be tested more frequently.
You can order a book to be printed and sent directly to reviewers
as they confirm they want them, bypassing the
risk of wasting money on extraneous copies, plus you don't need to
factor in
additional mailing costs.
Commodity - linked derivative instruments may involve
additional costs and
risks such
as changes in commodity index volatility or
factors affecting a particular industry or commodity, such
as drought, floods, weather, livestock disease, embargoes, tariffs and international economic, political and regulatory developments.
The fixed income
factors can be further adjusted to account for the yield curve and to add high yield credit
risk as an
additional factor.
There are
additional risks related to commodity investments due to large institutional purchases or sales, changes in exchange rates, government regulation, world events, economic and political conditions in the countries where energy companies are located or do business, and
risks for environmental damage claims,
as well
as natural and technological
factors such
as severe weather, unusual climate change, and development and depletions of alternative resources.
Beyond the bottom - up
risk assessment, we consider various
additional risk factors as we aim to optimize portfolio - level
risk, such
as ensuring appropriate diversification across stocks, sectors, and regions.
Fama and French later expanded their model to include fixed income, identifying term and default
as two
additional risk factors that explain returns for fixed income.
Factors include overall health, weather (dry, cold), the strength of the virus and if the dog is stressed,
Additional measures, such
as the regular administration of supportive remedies to dogs at
risk can enhance immunity and reduces the chance of clinical infection.
Therefore, they should require
additional disclosure on
factors such
as the carbon dioxide potential of fossil fuel reserves, to provide an indicator whether climate
risk is increasing or decreasing.
A variety of
factors may prevent children from knowing and exercising their legal rights, and these barriers are at
risk of being reinforced by
additional challenges such
as disability or family status.
But within the last decade, insurance companies have also begun using credit information
as an
additional factor to help predict which persons pose more
risk.
You can also choose a policy that offers more coverage, especially if your property has
additional risk factors, such
as a swimming pool or workout facility.
«develop a well - defined reference, or «baseline,» of good health
as well
as a rich data platform that may be used to better understand the transition from health to disease and identify
additional risk factors for disease»
The amount of Liability coverage you may want to purchase depends on the value of your possessions and your net worth,
as well
as your living situation (roommates, pets,
additional risk factors, etc.).
Applying for life insurance
as a skydiver will trigger an
additional mortality cost
factor as would a scuba diver, drag racer and any other sports classified
as high
risk.
If a private pilot has
additional adverse
risk factors, such
as an aviation violation or history of epilepsy, life insurance carriers may require the aforementioned aviation exclusion rider.
This can allow for
additional growth potential (
as well
as additional risk, so it is important to also be aware of this
factor).
If you own your vehicle outright, the decision about whether to purchase this
additional coverage is personal and is dependent on
factors such
as the value of your vehicle and your personal
risk assessment.