Not exact matches
Current therapies include surgery, for example replacing the weakened part of the aorta, and medical treatments such
as beta -
blockers or
angiotensin receptor blockers.
The blood pressure medication
angiotensin - converting enzyme inhibitors (ACEIs) appear to reduce major cardiovascular events and death,
as well death from all other causes, in patients with diabetes, while
angiotensin II
receptor blockers (ARBs) appear to have no such effect on those outcomes.
The two groups of drugs that are in most common use for that in pets are
angiotensin receptor blocking medications (ACE inhibitors, eg Fortekor ®, Lotensin ®, Enalapril ® aka ACE - Is)(ref1, rptref2, ref3) and
angiotensin receptor blockers (ARBs such
as telmisartan / Semintra ®).
Drugs such
as ACE - inhibitors and
angiotensin receptor blockers can benefit cats with chronic kidney disease by dilating blood vessels and supporting blood flow through the kidneys, lowering blood pressure, and also significantly reducing protein loss through the kidneys which can lead to the progression of disease, and so potentially improve survival in these patients.