Sentences with phrase «as antibodies used»

Not exact matches

Some types are very fast and easy to use but may not be ideal for breastmilk as they're going to damage the nutrients and antibodies.

To convey this to your husband, you can explain that years ago, people used to believe that breast milk lost its value after one year, but modern research has shown that a year is a minimum amount of time to nurse and breast milk continues to provide nutrients and antibodies for as long as the child continues to nurse.

Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

(borrowed from Dr Kitty) Breech Twins and higher order multiples Previous CS Pre-Eclampsia Placenta praevia Cervical incompetence Previous late stillbirth Previous premature birth Grand multiparty Age under 18 Age over 35 Smoking Drug use Severe mental health issue Epilepsy Type 1 diabetes Type 2 diabetes Gestational diabetes Asthma GBS positive Abnormal antibodies Transplant recipient Congenital heart disease Known foetal abnormality Immunosuppressive medication MS Physical disability Intellectual disability Hypothyroidism Hyperthyroidism Previous shoulder dystocia Previous 3rd or 4th degree tear Sickle Cell anaemia BMI under 18 or over 35 at conception Previous massive PPH APH in current pregnancy HIV / AIDS Hepatitis B or C Active TB IUGR Oligohydramnios Polyhydramnios Child previously removed from custody because of abuse Uterine abnormalities such as uterine septum or double uterus Previous uterine surgery for fibroids Chronic renal problems Hypertension Auto immune condition Previous stroke or blod clot Cancer Domestic violence or abusive home Prisoners Homeless women

Sharon used molecular biology methods to express and purify the virus peptide and NMR spectroscopy to analyze its structure as it is bound to neutralizing human antibodies.

For some years now, a new class of drugs called antibody - drug conjugates (ADCs) have been used, which work in two ways: they consist of an antibody that binds selectively to the tumor cell receptor and interrupts the signal to propagate; they also act as a transport vehicle for a chemical substance that enters the cancer cells with the antibody and triggers their death.

The company wanted to use it as a diagnostic marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.

I applied and was awarded an OIF to investigate whether dendritic - cell - specific antibodies can be used as therapeutic options for GVHD.

Researchers have made headway in understanding the H5N1 virus; they have created new vaccines and are looking into other possible treatments, such as using antibodies from survivors.

In tests in mice, a vaccine developed using human malaria parasite proteins — known as MSP -1-BBM — enabled the immune system to produce antibodies in the bloodstream.

If abnormal antibodies are discovered, researchers will notify the patient or caregiver, so that they may consider asking their health care provider about treatment options, such as using existing drugs that could suppress the production of the attacking antibodies.

As a researcher, Hockfield was among the first scientists to apply molecular biology to neuroscience, using monoclonal antibodies to study the brain.

Moreover, companies are moving into the use of new types of therapeutic proteins such as antibodies, which are only effective at high doses.

Using fluorescent antibodies designed specifically to light up the receptor in mice, the investigators observed it on vagus nerves, which serve as a main biochemical connection between airway cells and the brain.

The findings reveal that only those antibodies that target the prion protein tail are suitable for use as potential drugs.

CST has about 225 employees, and specializes in making antibodies to be used in research applications such as immunohistochemistry and flow cytometry.

Unlike other human antibodies under investigation that recognize both Zika and the closely related dengue virus, the antibodies used in this study exclusively target Zika, demonstrating a high specificity that could be important in avoiding potential side effects — such as enhanced dengue infection in regions where both viruses are endemic.

Approaches based on these five strategies have been used for streamlined, enhanced validation of more than 10,000 antibodies from more than 30 providers, targeting over 7,000 human proteins as part of the Human Protein Atlas program.

Using a mouse model of HSV - 1 as well as autopsied samples of human adult and fetal tissues, investigators from Dartmouth College's Geisel School of Medicine found that antibodies against HSV - 1 produced by adult women or female mice could travel to the nervous systems of their yet unborn babies, preventing the development and spread of infection during birth.

«We believe that the sensitivity to antibodies used as potential HIV treatment and to certain antiretroviral drugs can be decreased by cell - to - cell transmission.

They also hope to identify which potent antibodies could be used to treat people in emergency situations, such as a sudden outbreak or in the case of infection during pregnancy.

An antibody test can not be used as it only provides historical information about an infant's illness.

On the basis of isotope incorporation experiments and kinetic data, we propose that antibodies use H2O as an electron source, facilitating its addition to 1O2 * to form H2O3 as the first intermediate in a reaction cascade that eventually leads to H2O2.

Typically, detection of biomolecules such as proteins are performed using colorimetric assays or fluorescent labelling with a secondary antibody for detection, and requires complex optical detection equipment such as fluorescent microscopy or spectrophotometry.

In treating chronic diseases like rheumatism or Crohn's disease, such therapeutic antibodies are used as medication.

EdiGene Knockout Cell Lysates can be used to validate antibodies for specificity or used as high - quality negative controls for Western blot analysis.

In the Nature Biotechnology study, the researchers used it to anchor proteins, and they also showed that the technique works on tissue that has been previously labeled with either fluorescent antibodies or proteins such as green fluorescent protein (GFP).

While RNA expression doesn't prove protein expression, investigators can use the correlation as an easy way to check their antibodies.

For prevention studies, they injected mouse α - syn synthetic preformed fibrils into wild - type, normal mice, as a control, and then immediately treated the mice with Syn303, one of the MAbs used (or IgG, another type of common antibody, for the control mice).

Next, they removed large macromolecules like antibodies as well as salt fragments, and discarded all molecules that exert their biological effects through mechanisms other than protein - ligand interactions, are not used to treat diseases or are found only in topical products.

Using an antibody that binds and labels a specific viral protein, the researchers tracked the virus as it first infected nerves in the gut 2 or 3 days after the nasal spray and then successively appeared in the brain stem and midbrain and ultimately infected much of the rest of the brain within 10 days.

As a further therapeutic option, the researchers are pursuing the approach of using specifically developed antibodies against CEACAMs in order to fight diseases associated with the bacterium.

In an attempt to do this, the researchers used a technique known as radioimmunotherapy in which radioisotopes (unstable elements that release radiation) mounted on antibodies (protein molecules akin to infection search - and - destroy missiles) are injected into the body.

The researchers hope their study will lead to better therapies for neurodegenerative disorders, as well as help clinicians avoid the possible dangerous side - effects of using anti-prion protein antibodies for therapeutic purposes.

On Tuesday, an ethics committee at WHO declared it was ethical under the special circumstance to use unapproved Ebola treatments such as ZMapp, a mix of antibodies that has been tested in animals and was given to two U.S. health care workers who fell sick in Liberia.

The selective binding of specific bacterial species and / or strains in current practice requires expensive «cold - chain» reagents such as antibodies which often preclude using these processes outside of a hospital setting or in developing nations.

«This work points the way to using fully human antibodies as the next generation of antibody therapeutics,» Crowe said.

According to Wilson, monoclonal antibodies from (deliberately infected) animals were routinely used in the first half of the 20th century to try to treat diphtheria (an upper - respiratory illness that killed roughly 15,000 people annually in the early 1920s until a vaccine was formulated against it in 1924) and tetanus (a potentially fatal infection also known as lockjaw, because one of the muscles it destroys is in the jaw).

Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, called the new work a «significant advance,» noting in a statement that it «opens the way to producing [monoclonal antibodies] that potentially could be used diagnostically or therapeutically» for the flu as well as other infectious diseases such as hepatitis C and the human immunodeficiency virus (HIV), which can lead to full - blown AIDS.

For the past two decades, Lerner and his TSRI laboratory have helped pioneer techniques for discovering antibodies that can be used as therapies or scientific tools.

Because the body is not used to seeing this protein in the blood, it may develop antibodies to it, as if it were a foreign compound.

It seems as if antibody drugs used to get rid of sticky plaques that build up in brains with Alzheimer's may actually make the disease worse.

When the antibody was used as a standalone therapy, researchers saw a 95.9 percent reduction in cancer cells.

This research has important implications for the use of DNA - encoded monoclonal antibody technology as a platform for delivering the next generation of immunotherapies for cancer and many human diseases.

Just as cells of the immune system use antibodies to recognize pathogens, researchers in this study designed antibodies to recognize a protein over-expressed by these cancer cells, namely the protein mesothelin.

Then, using a chain of amino acids as a flexible linker, they attached mutated EPO to a specific antibody fragment.

Kobinger said he had no idea whether the antibodies had any effect on viral load in these patients, as they were given the experimental ZMapp on a «compassionate use» basis.

Using this approach as a template, researchers could substitute other types of antibodies and vaccines to target different tumors.

A type of antifungal antibody, called ASCA, is widely used as a diagnostic marker since it is highly elevated in the blood of patients with several chronic diseases including Crohn's.

When antibodies and other methods were used to dramatically deplete the supply of Tregs in mice, the researchers saw a dramatic jump in the numbers of activated dendritic cells and CD8 + T cells in pancreatic tumor tissue, as well as a slowing of tumor growth.