However, the first three findings were obtained from two studies, one of which was rated
as being at high risk of bias, and the fourth finding was lost following a sensitivity analysis.
Sensitivity analyses showed that all of the significant results for both physical and mental / developmental outcomes were lost once studies that were conducted in the East or that were categorised
as being at high risk of bias, had been excluded, and at follow - up.
Children were defined
as being at high risk if they were diagnosed or being treated for ADHD, or had behaviour problems and elevated scores (1.5 SD above the norm) on the Swanson, Nolan and Pelham IV ADHD screening measure.
One study was classified
as being at high risk of bias, and this examined a low intensity intervention.44 Inconsistent positive intervention effects were seen in this study, with most of these in one subgroup only.
(Oklahoma also is 1 of 6 states the U.S. Geological Survey recently identified
as being at high risk for earthquakes caused by human activities, such as oil and gas «fracking.»)
The Animal Emergency and Referral Center is also able to provide specialized anesthetic techniques for pets that are identified
as being at a high risk for anesthetic complications.
«There are 18 sites identified
as being at high risk for allowing the movement of aquatic nuisance species between the two basins,» Suski says.
Similarly, only half of the patients with OSA were categorized
as being at high risk for OSA on the Berlin Questionnaire, a sleep apnea screening tool, suggesting that these validated tools in the general population may not be useful for patients with cardiovascular diseases.
They classified first - born chimps and those born sixth or later
as being at high risk for «developmental instability» — a term for various prenatal perturbations such as hormonal irregularities associated with both first pregnancies and late ones.
As the breastfeeding intervention can not be blinded, we rated all studies
as being at high risk of bias for blinding of participants and personnel.
Borrowers with a poor credit score are seen
as being at a higher risk of defaulting on a loan.
• Biodiversity and environmental improvements activities should be prioritised
as they are at high risk of underfunding.
Should the results be confirmed by further studies, it is possible that patients with certain genetic changes in BRCA1 could be identified
as being at higher risk of breast and ovarian cancer.
A Dutch - Texan team found that most Houston - area drowning deaths from Hurricane Harvey occurred outside the zones designated by government
as being at higher risk of flooding: the 100 - and 500 - year floodplains.
If you have Celiac Disease, it is important that you know a bit about your thyroid gland,
as you are at a high risk of autoimmune thyroid disease.
Borrowers with a poor credit score are seen
as being at a higher risk of defaulting on a loan.
The animals served by the Spay Shuttle are those that have been identified
as being at highest risk for reproduction and then admission to the shelter, based upon breed, age and residence within high - intake neighborhoods in Knoxville and Knox County.
Purebred cats in general are regarded
as being at higher risk, and certain breeds, notably Persians and Burmese, seem to be most susceptible to FIP.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should
be considered in evaluating our outlook include, but
are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals
as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such
as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the
risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or
at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such
as U.S. export control laws and U.S. and foreign anti-bribery laws such
as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such
as the effect of The Tax Cuts and Jobs Act (the «TCJA») that
was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers,
as well
as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not
be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to
higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco
as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the
risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
«
At the moment the ICO space
is a mixture of
high risk exploration hybridised with a kickstarter feel — the traditional finance world knows what a blockchain token
is and will use it
as a form of digital bearer certificate to allow transferal of gold or digital cash,» he wrote.
The vision and foresight and confidence Jim France had in doing that... well, it
was definitely seen
as a
high -
risk move
at the time.
At some point, investors who
are conflating
high - yielding consumer staples stocks with bonds or who
are taking interest rate
risk in long - dated Treasurys will see drawdowns
as well.
«The global community will rightly expect the pace — alongside a
high level of diligence — to
be maintained so that people in affected communities and others living in countries
at risk of Ebola can have access to a vaccine
as soon
as possible.»
That comes with its own
risks,
as fraud tends to
be higher at peak buying times.
SAN FRANCISCO, May 3 Former U.N. chief Kofi Annan told Facebook Inc on Thursday that it should consider establishing a special team to respond more quickly to threats of sectarian violence in countries such
as Myanmar that
are at high risk.
If there
is a danger that monetary policy will
be seen
as «too difficult», there
is also a
risk that too much will
be expected of it or,
at least, that its success or failure will
be judged against an impossibly -
high standard: it can't cure the business cycle; it can't reduce inflation costlessly; and it can't
be operated with surgical precision.
The Triffin Dilemma,
as this problem
is known, points out that if foreign growth
is high enough relative to US growth that the need for US dollar reserves grows faster than the US economy, the resulting US current account deficit will require that the US sell assets fast enough, or that US obligations to foreigners grow fast enough, eventually to put the US economy
at risk.
Students who rack up a large amount of debt and begin their careers in an entry - level position can
be particularly
at risk, especially if they owe larger monthly payments on
high - interest debt, such
as private student loans.
Although a total of $ 800,000 in real estate crowdfunding sounds like a lot, I view it
as buying a $ 800,000 portfolio of 12 + different properties across the country
at much lower valuations and much
higher net rental yields compared to having $ 2,740,000 in one very expensive rental property in San Francisco that
is now
at risk of depreciating due to declining rents and new tax legislation that limits mortgage interest deduction and SALT deduction.
Indeed, once our estimated market return /
risk profile
is strictly negative (
as it
is at present), the negative implications for the S&P 500 aren't affected by the position of the market relative to that average, except that the market tends to experience
higher volatility once the market breaks that average.
This
is known
as «dollar - cost averaging» and can reduce the
risk of buying a large quantity of gold
at a
high price.
The companies
at the most
risk in such a scenario
are those such
as Continental Resources and Whiting Petroleum that not only based their budgets on
higher oil prices but still have balance - sheet issues to work out.
Specifically, Defendants made false and / or misleading statements and / or failed to disclose that: (i) the Company
was engaged in predatory lending practices that saddled subprime borrowers and / or those with poor or limited credit histories with
high - interest rate debt that they could not repay; (ii) many of the Company's customers
were using Qudian - provided loans to repay their existing loans, thereby inflating the Company's revenues and active borrower numbers and increasing the likelihood of defaults; (iii) the Company
was providing online loans to college students despite a governmental ban on the practice; (iv) the Company
was engaged overly aggressive and improper collection practices; (v) the Company had understated the number of its non-performing loans in the Registration Statement and Prospectus; (vi) because of the Company's improper lending, underwriting and collection practices it
was subject to a heightened
risk of adverse actions by Chinese regulators; (vii) the Company's largest sales platform and strategic partner, Alipay, and Ant Financial, could unilaterally cap the APR for loans provided by Qudian; (viii) the Company had failed to implement necessary safeguards to protect customer data; (ix) data for nearly one million Company customers had
been leaked for sale to the black market, including names, addresses, phone numbers, loan information, accounts and, in some cases, passwords to CHIS, the state - backed
higher - education qualification verification institution in China, subjecting the Company to undisclosed
risks of penalties and financial and reputational harm; and (x)
as a result of the foregoing, Qudian's public statements
were materially false and misleading
at all relevant times.
Charts that have violent up and down swings
are not considered to have solid chart structure
as I like to place my stops
at 10 - day
highs or 10 - day lows and if the charts have a tight pattern that will allow the trader to minimize
risk which
is what trading
is all about and if the chart has big swings your stop will
be further away allowing the possibility of larger monetary loss.
High - profile, successful, and gold - agnostic investment - world luminaries assess the macroeconomic
risks of radical monetary policies and reach a similar conclusion: This will end badly: — Seth Klarman: «All the Trumans (reference: a 1998 movie [The Truman Show] in which the main character's entire life takes place on a TV set which he perceives
as reality)-- the economists, fund managers, traders, market pundits — know
at some level that the environment in which they operate
is not what it seems on the surface....
Allowing free - market expression of gold prices may have
been seen
as a serious
risk at the
highest policy levels.
This
is evident in a number of developments, including: increased demand for
higher -
risk assets; the increase in «carry trades» — a form of gearing where funds
are borrowed short - term
at low interest rates and invested in
higher - yielding assets, often in other countries; growth in alternative investment vehicles such
as hedge funds; and growth in alternative investment strategies such
as selling embedded options (see Box A).
As usual, I don't place too much emphasis on this sort of forecast, but to the extent that I make any comments at all about the outlook for 2006, the bottom line is this: 1) we can't rule out modest potential for stock appreciation, which would require the maintenance or expansion of already high price / peak earnings multiples; 2) we also should recognize an uncomfortably large potential for market losses, particularly given that the current bull market has now outlived the median and average bull, yet at higher valuations than most bulls have achieved, a flat yield curve with rising interest rate pressures, an extended period of internal divergence as measured by breadth and other market action, and complacency at best and excessive bullishness at worst, as measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weaknes
As usual, I don't place too much emphasis on this sort of forecast, but to the extent that I make any comments
at all about the outlook for 2006, the bottom line
is this: 1) we can't rule out modest potential for stock appreciation, which would require the maintenance or expansion of already
high price / peak earnings multiples; 2) we also should recognize an uncomfortably large potential for market losses, particularly given that the current bull market has now outlived the median and average bull, yet
at higher valuations than most bulls have achieved, a flat yield curve with rising interest rate pressures, an extended period of internal divergence
as measured by breadth and other market action, and complacency at best and excessive bullishness at worst, as measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weaknes
as measured by breadth and other market action, and complacency
at best and excessive bullishness
at worst,
as measured by various sentiment indicators; 3) there is a moderate but still not compelling risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weaknes
as measured by various sentiment indicators; 3) there
is a moderate but still not compelling
risk of an oncoming recession, which would become more of a factor if we observe a substantial widening of credit spreads and weakness in the ISM Purchasing Managers Index in the months ahead, and; 4) there remains substantial potential for U.S. dollar weakness coupled with «unexpectedly» persistent inflation pressures, particularly if we do observe economic weakness.
When investing with peer - to - peer lending platforms such
as LendingCrowd, your actual return may
be higher or lower
as your capital
is at risk.
As less mature stocks have
higher growth potential, a hypothetical investor with a significant portfolio allocation into the Fund would likely
be looking
at obtaining
higher returns for his or her portfolio, with commensurately
higher risk.
This method
is regarded
as the most profitable but comes
at a
higher risk of losing all the investments.
What looks like a bubble
at first glance can
be viewed
as a long - term strategy for funding drug development, one that involves private funds, pharmaceutical companies and the public markets, along with a good deal of
risk — and, sometimes,
high reward.
«Conversely, Marketing rated 18 % of salespeople
as poor — the lowest «poor» rating in the group — while their tolerance for
risk rating
was much
higher,
at 7.1 %.»
I
'm currently not involved in this market
as the chart structure
is terrible
as the 10 day low stands
at 62.01
as the monetary
risk is too
high, however, I
am certainly not recommending any type of short position
as this trend
is strong
as the fundamental and technical picture remains bullish.
Jumbo loans
are nonconforming loans that come with
higher interest rates to offset the increased
risk on the part of lenders who issue them
as more money
is at stake.
The suggestion, however, that God cares about the world
as one cares about one's own body, that
is, with a
high degree of sympathetic concern, does not imply that all
is well or the future assured, for with the body metaphor, God
is at risk.
The great interest of the study arises from the fact that,
as the years went by, the researchers noticed that many of the children they had identified
as «
at high risk» (i.e., children subject to four or more serious disadvantages)
were able to lead satisfying and socially productive lives
as adults.
Oats
are great for stabilizing your blood sugar level
as a result of the combination of
high fiber and complex carbohydrates which slows down the rate
at which this grain
is converted to simple sugars thereby preventing blood sugar spikes and reducing the
risk of developing diabetes
«Initiatives such
as the Courtauld Commitment, aimed
at reducing the environmental impact of the grocery sector, along with
high profile food recalls, mean that suppliers and retailers
are giving increasing priority to driving out waste, reducing
risk and optimising performance,» points out Alan Mutch.
Harvey Norman
is now
at risk of losing its entire equity investment and some or all of its debt exposure if the receivers — Peter Anderson, William Harris and Matthew Caddy of McGrath Nicol — fail to find a buyer willing to pay a
high enough price to repay National Australia Bank, which
as secured creditor ranks ahead of Harvey Norman.