Sentences with phrase «as better animal models»

There's more to these findings than just lofty philosophical quandaries, though: If ravens really do possess a level of social cognition comparable to humans and other large primates, the birds might serve as better animal models to study this kind of behavior in the lab — which could help scientists understand why some humans are better at this kind of inference than others, and why some individuals can't manage it at all.

Herzberg said his stories dealt «with obviousness that is not obvious... the stethoscope as the eternal symbol of doctors, mice as our best animal model, eels as simple, almost boring, river fishes.

Wild H5N1 viruses can not latch on tothe cells in a person's nose and throat, but the mutant strains created by Fouchier and Kawaoka can spread between ferrets, which are viewed as a good animal model of flu transmission between humans.

The finding, by researchers at the University of Illinois at Chicago College of Medicine, was reported July 16 at the Alzheimer's Association International Conference in Copenhagen by Mary Jo LaDu, who in 2012 developed a transgenic mouse that is now regarded as the best animal model of the human disease.

Furthermore, the heterozygous knock in mouse serves as a better animal model of the human disorder, as compared to the homozygous mouse, given that Huntington disease homozygosity is very rare in humans.

Not exact matches

[104] In place of WS, animal protectionists hold up their work with sheep producers of Marin County, California as a better coyote management model.

They then tested the contributions of samples from breast milk as well as individual molecules in both animal and cellular models of infection, measuring the length of time until resolution.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

And the enrichments may make the animals better at what they do: serving as important models for human disease.

As noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.&raquAs noted by Dr. Vicki Ellingrod — the Chair of this session, «Current state - of - the - art research in both animal models as well as humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.&raquas well as humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.&raquas humans point to the link between the gut microbiota and mood and anxiety models, as well as the potential for psychiatric medications to directly affect the gut microbiome.&raquas well as the potential for psychiatric medications to directly affect the gut microbiome.&raquas the potential for psychiatric medications to directly affect the gut microbiome.»

While mouse models have traditionally been used in studying the genetic disorder, Deng said the animal model is inadequate because the human brain is more complicated, and much of that complexity arises from astroglia cells, the star - shaped cells that play an important role in the physical structure of the brain as well as in the transmission of nerve impulses.

The study — which looked at the action of Substance P within nerve cells in the lab and in animal models — focused on acute pain, but Professor Gamper aims to look at its role within chronic pain as well.

Chief among the criticisms were the animal's hindlimbs, significantly smaller compared with other large predatory dinosaurs, as well as other researchers» theoretical Spinosaurus models.

«But really, there is an opportunity with appropriate animal models to make a huge difference for the human community as well.»

Researchers at the University of Minnesota have developed an animal research model for facioscapulohumeral muscular dystrophy (FSHD) to be used for muscle regeneration research as well as studies of the effectiveness of potential therapies for FSHD.

«There's a growing demand, as animal models aren't mirroring the diseases too well,» says David Dexter, director of the bank.

CDNF has shown strong neuroprotective and even restorative properties in animal models of Parkinson's disease as well as spinal and peripheral nerve injuries.

Early treatments in animal models in vivo with hotter lasers didn't work as well.

Significantly, disabling both anti-apoptotic proteins, Bcl - 2 and Bcl - xL, in conjunction with Mcl - 1, caused profound cell death of leukemia cells in the test tube as well as in animal models of AML.

Here, we used Splenda as a means to test the combined effect of the commercial ingredients and used one of the best animal models of ileal Crohn's disease.»

DNA vaccines have been studied in animal models of viral, bacterial, and parasitic disease, as well as animal models of tumors.

The BUSM researchers believe the data from this study and those reported by others in animal models as well in clinical studies strongly suggest that Avodart may have serious adverse side effects that were not obvious several years ago.

Serotonin [5 - hydroxytryptamine, (5 - HT)-RSB- function influences normal fear as well as pathological anxiety, behaviors critically dependent on the amygdala in animal models and in clinical studies.

The next step will be to demonstrate efficacy in larger animal models, as well as test whether this approach can be used to protect against or treat other diseases.

Though the scientists don't know if such individual and pack behavior is a common occurrence, observations like these on Isle Royale provide insight into how animal societies function as well as the vicissitudes of the food chain cycle on Isle Royale, also helping to inform other models of the natural world.

These inhibitors effectively targeted and blocked Msi expressing cells, resulting in halted tumor growth in animal models as well as in patient - derived cancer cells, which harbor more complex mutations and are uniformly drug - resistant.

«Future studies on maternal smoking and other environmental, genetic, and epigenetic factors, as well as animal models, should allow identification of the biological mechanisms responsible for these associations.

Brendan Wintle at the University of Melbourne, Australia, has developed an alternative model that includes data on previous searches in remote regions, as well as aspects of the animal's biology and behaviour.

The new NIH project includes collaborators with expertise in animal modeling as well as device manufacturing.

No, studies using animal models of human disease as well as «humanized mice» are expressly forbidden.

According to the model, an animal that bases its decisions only on its current energy reserves can survive almost as long as one that uses its brain to calculate the best thing to do.

«The development of this microfluidic lung model, as well as other organs - on - chip, holds the promise of improving the physiological relevance of cellular models for more accurate prediction of the effects of toxicants and drugs on humans, and for reducing the use of animals in medical and pharmaceutical research,» said Sonia Grego, Ph.D., research scientist at RTI and the project's principal investigator.

Studying these symptoms earlier in the animal model gives researchers more time to monitor the progression of the disease as well as assess the efficacy of potential therapeutics and to determine if and when the course of the disease could be altered.

Using human and animal models, these studies may help explain why position in social hierarchies strongly influences decision - making, motivation, and altruism, as well as physical and mental health.

In various talks, interviews and articles, he suggested that a mathematical brain model would deliver such fundamental breakthroughs as simulation - driven drug discovery, the replacement of certain kinds of animal experiments and a better understanding of disorders such as Alzheimer's.

Investigating mouse models for biological for research The congress aims to promote the International Mouse Phenotyping Consortium (IMPC) mouse lines, importance of mouse phenotyping & clinical and drug discovery collaboration, to present progresses performed by IMPC with regards CRISPR editing genome, rare diseases, microbiota and ageing pipeline, as well as illustration of examples of scientific projects about «Animal models for human diseases» and recent developments in mouse models phenotyping imaging.

Understanding cattle movement patterns as well as the connectivity of the various sectors of the U.S. cattle industry and incorporating these in the models would allow USDA Animal Plant Health Inspection Service (APHIS) Veterinary Services (VS) to develop more effective regulations and control strategies for various animal diseases, including boviAnimal Plant Health Inspection Service (APHIS) Veterinary Services (VS) to develop more effective regulations and control strategies for various animal diseases, including bovianimal diseases, including bovine TB.

We carry out translational research programmes to develop infectious disease vaccines, therapeutics and diagnostics using animal models of tuberculosis, influenza, HIV / AIDS, Clostridium difficile, meningococcal disease, chlamydia, burkholderia and anthrax, as well as emerging viral diseases such as Crimean Congo haemorrhagic fever.

Now, researchers at Harvard and Massachusetts General Hospital (MGH) and their colleagues have shown that amyloid - β can protect against yeast and bacterial infections in two animal models, as well as in cultured human cells.

We recently developed such an animal model and propose to use it to study the role of complement in AMD as well as develop a gene therapy.

Achieving that goal, says Ingber, will require proving that the devices are «as good as or better than animal models.»

We have learned a fair amount from the neurologic genetic diseases, but we and others also studied these cells in the laboratory as well as in animal models of brain injury.

Scientists could also infect animal models, such as mice, with the virus to get a better understanding of how the pathogen affects the neural system.

This network is composed of a central animal facility (PBES) and several technological platforms: production of mutant animals, vectorology and genetic analysis as well as infectious models analysis.

To take a finding in basic research, such as identifying a mutant protein that drives a particular cancer, and develop a drug that inactivates the protein and performs well in cells in the lab and in animal models can take years, if not decades.

We have created the first such animal model through the expression of C3, and it recreates many of the features of dry as well as wet AMD.

In large animal models of heart failure, the researchers found that gene therapy delivery of high dose SUMO - 1 alone, as well as SUMO - 1 and SERCA2 together, result in stronger heart contractions, better blood flow, and reduced heart volumes, compared to just SERCA2 gene therapy alone.

Biomedcode welcomes suggestions and proposals for the development of novel animal disease models as well as for the generation of animals humanized for targets of interest.

While ChrX has been implicated in related traits in animal models as well as in 10 % of human Mendelian disorders, its role in human aging is largely unknown.

His research interests are focused on the molecular genetics of the inherited myopathies and neuromuscular junction disorders and the study of animal models of these disorders as a means to understand their pathophysiology as well as to develop means to monitor disease progression and therapeutic interventions.