Sentences with phrase «as bone marrow transplantation»

Not exact matches

The work was on the role of interleukin - 1 in the pathology of graft - versus - host disease (GVHD), the mechanism by which the new immune system, which a patient receives as a bone marrow transplant, attacks the patient's body following the transplantation.

Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow — blood stem cell — transplantation safer and, as a result, more widely available to the millions of people living with blood disorders like sickle cell anemia, thalassemia, and AIDS.

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

Trapnell and Suzuki were prompted to test the novel macrophage transplantation therapy by studies showing that resident macrophage populations (such as those residing in the lung) can self - maintain without the cells having to regenerate directly from the bone marrow.

Dr. Cooper joined MDACC in 2006 as section chief of cell therapy at the Children's Cancer Hospital, where he cared for children undergoing bone marrow transplantation and led scientific efforts to develop new treatment approaches that pair genetic engineering with immunotherapies.

If validated in clinical trials, the signature would help physicians better identify which AML patients would benefit from chemotherapy and which patients have a prognosis so grave that they may be candidates for more aggressive treatments such as bone - marrow transplantation.

In a study published in the June 12 edition of Science, they detail how a new drug repaired damage to the colon, liver and bone marrow in animal models — even going so far as to save the lives of mice who otherwise would have died in a bone marrow transplantation model.

«Until now, physicians have taken a «wait and see» approach to antiviral therapies following transplantation,» says Toor, a hematologist - oncologist in the Bone Marrow Transplant Program and member of the Developmental Therapeutics research program at VCU Massey Cancer Center as well as professor in the Division of Hematology, Oncology and Palliative Care at the VCU School of Medicine.

«These results are an exciting early indication that this gene therapy is well tolerated and effective in infants as young as 2 months old with this devastating inherited immune disorder,» said Ewelina Mamcarz, M.D., an assistant member of the St. Jude Department of Bone Marrow Transplantation and Cellular Therapy.

One leukemia patient but not another may be eligible for a bone marrow transplantation as a first line of treatment — a harsh, costly, but potentially curative treatment.

We offer a full spectrum of treatment services on site, including chemotherapy and radiation therapy, pre - and post transplant care for blood and bone marrow stem cell transplantation, as well as cancer screenings and supportive care services such as patient support groups and a cancer resource center.

In spite of her challenging beginning, Torok - Storb has played an important part in the development of bone marrow transplantation as an effective therapy for blood diseases.

«Given the importance of stem cell - based transplantation therapies as well as the clinical significance of tumor metastastis to the bone marrow, there is great therapeutic potential in understanding these cellular interactions,» Sipkins said.

This condition may be present at birth, or it may be caused by certain infections (such as human immunodeficiency virus or HIV), or by certain cancer therapies, such as cancer - cell killing (cytotoxic) drugs, radiation, and bone marrow transplantation.

Today, Lenti - D therapy appears to be poised as a real treatment option for cerebral ALD and opens the door to other neurological diseases where bone marrow transplantation is currently used.

In 1993, he joined the Divisions of Experimental Hematology and Bone Marrow Transplantation at St. Jude Children's Research Hospital in Memphis, where he was appointed director of the cell and gene therapy laboratories, as well as chair of the institutional review board.

Their research focused on evaluating the safety and efficacy of autologous bone marrow - derived stem cell transplantation in individuals with type 2 diabetes with good glycemic control as well, which emerged as an important aspect in the transplantation group as well as in the non-transplanted group.

To qualify under Major Organ Transplant, the Insured Person must undergo a transplantation procedure as the recipient of a heart, lung, liver, kidney or bone marrow, and limited to these entities.

The role that a person has in a traumatic experience is a major factor that increases the likelihood of developing PTSD.31 Specifically, a previous study found that parents whose children underwent bone marrow transplantation might experience PTSD, largely because of their being unable to be as supportive to their children and as actively involved in their care as they were during outpatient treatments, with high stress levels and feelings of helplessness.5 Those investigators hypothesized that loss of parental roles might be a factor contributing to the development of PTSD among parents whose children undergo bone marrow transplantation.