His cases involve injuries of the utmost severity such
as brain and spinal cord injuries, amputations and multiple orthopaedic injuries, as well as debilitating pain syndromes and functional neurological disorders.
Our primary focus is on catastrophic injuries such
as brain and spinal cord injuries and wrongful deaths, but we willguide and represent you during any personal injury case.
As a serious injury law firm GJEL specializes in major injuries including complex injuries such
as brain and spinal cord injuries which can require complex litigation.
Their breakthrough, published today in the scientific journal PLoS Biology, could eventually help develop tools to repair nerve cells following injuries to the nervous system (such
as the brain and spinal cord).
The bodies are returned to families for funerals; even an open casket funeral is possible
as the brain and spinal cord are removed from the back.
Not exact matches
The
spinal cord may be best understood
as a thick data cable that processes
and transmits the constant stream of electrical impulses that flow between your
brain and the rest of your body, enabling motion
and sensation.
Bacterial meningitis is
as infection that can cause inflammation on the membrane covering the
brain and spinal cord.
In rare cases, vomiting can be a symptom of a serious condition, such
as a blockage of the digestive tract (pyloric stenosis), an infection (meningitis) of the fluid (cerebrospinal fluid)
and tissues (meninges) that surround the
brain and spinal cord, or Reye syndrome.
Because of its ability to finely tune the signals it generates, an MRI can also show softer, more intertwined tissues — such
as in the
brain,
spinal cord and musculoskeletal system — in rich detail.
The research group came up with bypassing the functioning
brain and locomotion center with the computer to compensate lost pathways
as a way to enable individuals with
spinal cord injury to regain walking ability.
Folic acid has long been touted
as an important supplement for women of childbearing age for its ability to prevent defects in the baby's developing
brain and spinal cord.
Neural networks in the
spinal cord, locomotion center are capable of producing rhythmic movements, such
as swimming
and walking, even when isolated from the
brain.
Known
as the blood -
brain barrier, cells that line the
brain and spinal cord are tightly packed, making it difficult for anything besides very small molecules to cross from the bloodstream into the central nervous system.
However, a mystery remains
as to why opsins are also expressed in the mammalian
brain and spinal cord, where they may not receive sufficient light to be light activated.
«Someday AAV9 may help us treat
spinal cord injury
as well
as diseases of the
spinal cord and brain by carting genes right to the place they're needed,» Kaspar says.
Amyotrophic lateral sclerosis, also known
as Lou Gehrig's disease, is marked by a cascade of cellular
and inflammatory events that weakens
and kills vital motor neurons in the
brain and spinal cord.
Researchers envision the e-dura being used in people with
spinal cord injuries,
as a
brain implant
and even to correct nerve damage in other parts of the body.
The «e-dura» implant is made from a silicone rubber that has the same elasticity
as dura mater, the protective skin that surrounds the
spinal cord and brain, explains Stéphanie Lacour, a professor at the school of engineering at the Swiss Federal Institute of Technology in Lausanne.
Infection normally begins in the lungs
as TB
and can spread to the
brain and spinal cord, causing swelling
and restricting blood flow.
That's what happens in many diseases of the nervous system, such
as multiple sclerosis (MS),
spinal cord injuries, stroke, neonatal
brain injuries,
and even Alzheimer's disease.
It is produced by the
brain and spinal cord into early adulthood
as it is needed for many developmental processes,
and although earlier studies of human white matter hinted at its involvement in skill learning, this is the first time it has been confirmed experimentally.
Clyde Francks, head of the MPI research group «
Brain and behavioral asymmetries» and Research Fellow at the Donders Institute at the Radboud University, explains, «We think that these very early left - right differences in the spinal cord may act to trigger some of the later asymmetries of the brain, such as the eventual dominance of the left hemisphere for language functions in most adults&ra
Brain and behavioral asymmetries»
and Research Fellow at the Donders Institute at the Radboud University, explains, «We think that these very early left - right differences in the
spinal cord may act to trigger some of the later asymmetries of the
brain, such as the eventual dominance of the left hemisphere for language functions in most adults&ra
brain, such
as the eventual dominance of the left hemisphere for language functions in most adults».
Infection with Bb led to many histopathologic findings in infected animals not treated with dexamethasone, such
as leptomeningitis, vasculitis, focal inflammation in the
brain and spinal cord,
and necrotizing focal neurodegeneration
and demyelination in the cervical
spinal cord.
Microglia are present throughout the
brain and spinal cord, are constantly monitoring their environment,
and can be switched on or activated to perform different functions such
as control inflammation, destroy pathogens, clean up the debris from dead or damaged cells,
and seal off the site of an injury.
Children progressively lose muscle control
as the tumor rapidly attacks the pons, a region deep inside the
brain that connects the
brain to the
spinal cord,
and is difficult to reach
and surgically remove.
Now, to enable widespread gene delivery throughout the central
and peripheral nervous systems, Caltech researchers have developed two new variants of a vector based on an adeno - associated virus (AAV): one that can efficiently ferry genetic cargo past the blood -
brain barrier;
and another that is efficiently picked up by peripheral neurons residing outside the
brain and spinal cord, such
as those that sense pain
and regulate heart rate, respiration,
and digestion.
The trigger for the immune response, the molecule interleukin - 33, is concentrated in what is known
as «white matter» in the healthy
brain and spinal cord.
SMA is caused by a mutation in a gene that is vital for the survival of nerve cells that connect the
brain and spinal cord to the muscles, known
as motor neurons.
There are different types of abnormalities of the
brain and spinal cord, which may result in varying degrees of disability such
as muscular paralysis, water in the head, incontinence
and motor disorders.
Myelin, the fatty coating that protects neurons in the
brain and spinal cord, is destroyed in diseases such
as multiple sclerosis.
This promises to make proton therapy an option for thousands more cancer patients by reducing the risks of healthy tissue being damaged during treatment, particularly in vulnerable parts of the body such
as the
brain, eye
and spinal cord.
Specifically, stem cell scientists at McMaster can now directly convert adult human blood cells to both central nervous system (
brain and spinal cord) neurons
as well
as neurons in the peripheral nervous system (rest of the body) that are responsible for pain, temperature
and itch perception.
But where neuroscientists are accustomed to seeing only vanilla when it comes to astrocytes — viewing all of them
as similar despite their different locations in
brain and spinal cord — they now will have to imagine «31 flavors» or more.
Lou Gehrig's disease, also known
as amyotrophic lateral sclerosis, or ALS, attacks muscle - controlling nerve cells — motor neurons — in the
brain, brainstem
and spinal cord, leading to progressive weakness
and eventual paralysis of muscles throughout the body.
If the approach also works with human cells, it could eventually lead to cell therapies for diseases like inherited leukodystrophies — disorders of the
brain's white matter —
and multiple sclerosis,
as well
as spinal cord injuries.
In a study recently published in the journal Scientific Reports, researchers in USF's Center of Excellence for Aging
and Brain Repair say the results of their experiment are an early step in pursuing stem cells for potential repair of the blood -
spinal cord barrier, which has been identified
as key in the development of ALS.
Fehlings suggests that
brain - machine interfaces could one day be combined with several other treatment strategies — such
as stem cells
and drugs — to produce much greater overall benefit for people with damaged
spinal cords.
Four young men who have been paralyzed for years achieved groundbreaking progress — moving their legs —
as a result of epidural electrical stimulation of the
spinal cord, an international team of life scientists at the University of Louisville, UCLA
and the Pavlov Institute of Physiology reported today in the medical journal
Brain.
He said this technology may one day help patients affected by various
brain and spinal cord injuries such
as strokes
and traumatic
brain injury.
A particular type of macrophage known
as microglia are found throughout the
brain and spinal cord — in progressive forms of MS, they attack the CNS, causing chronic inflammation
and damage to nerve cells.
Unsupervised communication For paraplegics who lose motor
and sensory function
as a result of amyotrophic lateral sclerosis,
spinal cord injury or stroke - induced
brain damage, simply communicating can be extremely difficult, if not impossible.
This change in electrical charge of the neuron is what propagates
and sends the signal to the
spinal cord and then to the
brain to register
as a sensation, such
as pain or pressure.
Amyotrophic lateral sclerosis (ALS), also known
as Lou Gehrig's disease, is a debilitating neurodegenerative disorder that leads to paralysis
and death due to the loss of motor neurons in the
brain and spinal cord.
When this vasculature — the blood -
brain barrier (BBB)-- ruptures, blood proteins can enter into the
brain and cause edema
and neuronal damage in a variety of neurological diseases, such
as stroke, multiple sclerosis, Alzheimer's disease,
and spinal cord injury.
Her aim is to understand, at the molecular level, the mechanisms that control communication between the
brain, immune system,
and blood vessels — with the ultimate goal of designing new therapies that slow, stop, or reverse the progression of a wide range of neurological disorders, such
as MS. Recently, Dr. Akassoglou's lab identified how microglia — a type of immune cell that acts
as the
brain's first line of defense — are activated when fibrinogen enters the
brain or
spinal cord.
The study conducted in the laboratory of Don Cleveland, Ph.D., UCSD Professor of Medicine, Neurosciences
and Cellular
and Molecular Medicine
and member of the Ludwig Institute for Cancer Research, shows that therapeutic molecules known
as antisense oligonucleotides can be delivered to the
brain and spinal cord through the cerebrospinal fluid (CSF) at doses shown to slow the progression of ALS in rats.
Adeno - associated viral (AAV) vectors are the most frequently used gene - transfer tools in the study of the
brain and spinal cord, which together are known
as the central nervous system (CNS).
MS is an inflammatory disease in which the protective myelin sheathing that coats nerve fibers in the
brain and spinal cord is damaged
and ultimately stripped away — a process known
as demyelination.
(1,2) The various forms of aggregated
AS first appear in neurons in the periphery of the body (that is, outside of the
brain and spinal cord),
and then invade the
brain, starting from the base of the skull
and slowly spreading their way forward across the
brain over the course of the disease.
Some amphibians — such
as salamanders — are famous for their superhero - like ability to regenerate heart,
brain,
spinal cord, tail
and even whole limb tissue throughout their life.