Sentences with phrase «as cadherin»

The groundbreaking study identified a protein, known as cadherin - 22, as a potential factor in cancer metastasis, or spread, and showed that hindering it decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.

Not exact matches

These findings suggest that the therapeutic protein was able to interact normally with its binding partners among the USH1 molecular complex (the proteins cadherin 23, protocadherin 15, myosin VIIA and harmonin), as required for the mechanoelectrical transduction apparatus of the hair bundle to function correctly.

Dr. Menko, together with first author Caitlin Logan, MD, PhD, and second author Caitlin Bowen, was looking at a mouse that had been engineered to stop producing a key developmental protein called N - cadherin just as the lens was beginning to form.

Nectins tend to bind heterophilically, meaning that they adhere more strongly to nectins of a different type, and have been shown to serve as recruiters for cadherin molecules.

Cadherin - 22 is located on cell surfaces, allowing hypoxic cancer cells to stick together and migrate collectively as a group, said Uniacke.

«Our findings suggest that cadherin - 11 is important for cancer progression as well as rheumatoid arthritis — for reasons we do not fully understand.

As a doctoral student in the lab of Drs. Margaret Wheelock and Keith Johnson at the University of Toledo, Dr. Islam focused on identifying a link between cadherins (a family of cell adhesion proteins) and tumorigenesis (start of cancer cell formation).

Central to adherens junctions is a protein known as E-cadherin, or epithelial cadherin.