In patients with severe neurologic compromise or signs of sepsis, IV antibiotics, such
as cefazolin, should be considered for the first 5 to 7 days.
In patients with severe neurologic compromise or signs of sepsis, IV antibiotics, such
as cefazolin, should be considered for the first 5 to 7 days.3 If fungal disease is confirmed, discospondylitis should be treated with antifungal drugs, such as fluconazole or itraconazole.