Sentences with phrase «as cell injury»

«The frequency of cell fusion events in vivo is not known, although cell fusion is thought to occur under some circumstances such as cell injury, inflammation, and viral infection.

Not exact matches

According to the report, the team member who went in to the brothel as a decoy customer was beaten and robbed of his cell phone and cash, but escaped with the girl without further injury.

Cells grow, repair and rebuild during sleep, making it essential to athletic performance, as well as injury recovery and prevention.

The decision was seen as an effort to mollify the religious fundamentalists at the core of Bush's political support who are ideologically opposed to deriving the cells from frozen embryos in fertility clinics and scientists and patients who hope that the cells could be used to help patients with Parkinson's, Alzheimer's, spinal - cord injuries, and diabetes.

This knowledge is important, as iPSCs hold great promise in the field of regenerative medicine, as they can provide a single source of patient - specific cells to replace those lost to injury or disease.

Anything that causes tissue injury — including infection or illness as well as surgery — can activate various immune cells and cause inflammation.

The research, published in the current issue of the journal Science, demonstrates that brain cells, known as astrocytes, which play fundamental roles in nearly all aspects of brain function, can be adjusted by neurons in response to injury and disease.

The team produced 11 stem cell lines from 11 men, women, and children with conditions such as diabetes, spinal cord injury, and inherited immune deficiency.

Stem cell scientists fear that the Texas bill would lend legitimacy to the field, provide false hope to patients, and even embolden hucksters touting stem cells as miracle cures for everything from diabetes to multiple sclerosis to spinal injuries.

A person with spinal injuries today went down in history as the first to receive a treatment derived from human embryonic stem cells (hESCs).

«Proper blood cell production is dependent on functioning hematopoietic stem and progenitor cells that are destroyed during conditioning procedures for transplantation or following bone marrow injury,» said the study's first author Kevin A. Goncalves, who performed this research as part of his PhD studies in cellular and molecular physiology at the Sackler School.

Yonju Ha, a lead author of this article, said that further studies on this receptor and its role in white blood cell recruitment following tissue injury may aid in the development of new interventions for diseases associated with nerve injury, such as TON, stroke, diabetic retinopathy and glaucoma.

To find out, Deb and his co-authors genetically tagged cardiac fibroblasts in mice and watched as they transitioned into bone - forming, osteoblast - like cells after heart injury.

Cells in newts can change in response to injury — a process known as dedifferentiation.

While the regenerative capability of brain cells, in the hippocampus — the part of the brain responsible for learning and memory — slows down as part of the aging process, the Rutgers scientists determined that the process that occurred after a head injury was related to injury and not age.

Organisms like zebra fish readily dedifferentiate cells near the injury, undergoing a cellular age regression in which «they form something like stem cells, although they are not quite the same as stem cells,» says Keating.

Since the same stem cells are responsible for helping heal the skin after injury, the study raises the possibility that Tregs may play a key role in wound repair as well.

British newspapers reported this weekend that Ian Wilmut, the University of Edinburgh biologist who led the team that in 1997 cloned Dolly the sheep, is getting out of the cloning business in light of the new findings, which seem to offer researchers a likely new source of stem cell lines for basic research that could one day lead to new treatments and perhaps cures for spinal injuries, diabetes and debilitating disorders such as multiple sclerosis and Parkinson's disease.

Microglia are present throughout the brain and spinal cord, are constantly monitoring their environment, and can be switched on or activated to perform different functions such as control inflammation, destroy pathogens, clean up the debris from dead or damaged cells, and seal off the site of an injury.

In some, the cells were always active; in others, such as the liver, they multiplied only when tissues sensed injury.

Treating the potentially blinding haze of a scar on the cornea might be as straightforward as growing stem cells from a tiny biopsy of the patient's undamaged eye and then placing them on the injury site, according to mouse model experiments conducted by researchers at the University of Pittsburgh School of Medicine.

They used a gel of fibrin, a protein found in blood clots that is commonly used as a surgical adhesive, to glue the cells to the injury site.

«Secondary benefits of this trial include the significant improvement in clinical care for children with sickle cell disease at each of the 29 sites because each location had a designated hematologist, neurologist, neuroradiologist and psychologist working as a team to identify and decrease further injury to the brain in this vulnerable population.»

Cells in our bodies respond to stressors such as viral infections, starvation, and injury in the same way: by restricting the production of new proteins.

Pretreating the animals with leucine make the reserve stem cells more sensitive to radiation and less able to regenerate tissue following radiation injury, while rapamycin protected the reserve stem cells as they were more likely to remain dormant.

Along with his colleagues, Shaqfeh has now created the first simplified computer model of the process that forms that layer — a model that could help to improve the design of artificial platelets and medical treatments for trauma injuries and for blood disorders such as sickle cell anemia and malaria.

Lengner cautions, however, that rapamycin can not be used as a stand - in for calorie restriction, as it would linger and continue to block mTOR activation even following injury, hindering the ability of the reserve stem cells to spring into action and regenerate intestinal tissue.

Their breakthrough, published today in the scientific journal PLoS Biology, could eventually help develop tools to repair nerve cells following injuries to the nervous system (such as the brain and spinal cord).

IL - 33 is a cytokine, a small protein that signals immune cells such as T cells to travel to a site of infection or injury.

They found that these skin - resident immune cells function as «first responders» to skin injuries in part by producing the molecule known as interleukin - 17A (IL - 17A), which wards off infection and promotes wound healing.

These cells spring into action following bone marrow transplants, bone marrow injury and during systemic infection, creating new blood cells, including immune cells, in a process known as hematopoiesis.

First, when muscle is damaged by injury or degenerative disease such as muscular dystrophy, muscle stem cells — or satellite cells — need to differentiate into mature muscle cells to repair injured muscles.

The cells overproduce and secrete collagen, as they would in a real injury.

But last April he also voted for the HOPEAct, a Bush - supported «compromise» bill that would open up federal funding for research that does not involve the creation, destruction, or injury of embryos; seeing as there are not yet any embryonic stem cells lines that meet this condition (ACT hasn't yet proven that their technique poses no «risk of injury»), the HOPE funding would only be available for non-embryonic stemcells.

He and other supporters argued unsuccessfully that the move would pave the way to cures for conditions such as spinal cord injuries and sickle - cell anemia as well as degenerative disorders such as multiple sclerosis and Parkinson's and Alzheimer's diseases.

In addressing the first question, the study showed that the brain's immune cells, microglia, which are known to become activated by LPS exposure as well as in most brain injuries and diseases, begin spewing out pro-inflammatory factors that change astrocytes» behavior.

These cells are being tested widely as a way to repair tissue lost in diseases as varied as spinal cord injury, heart failure and diabetes.

Those two papers were groundbreaking because they put forward a method for generating stem cells far simpler than any previously reported, a development that could advance regenerative medicine, in which scientists try to grow replacement tissues as a treatment for diseases and injuries.

About two weeks following injury, the cells responded to light as if they were interneurons.

You would lose them as you aged or as the result of injury or disease,» said Prof. Offen, who also serves as Chief Scientific Officer at BrainStorm, a biotech company at the forefront of innovative stem cell research.

The research reveals that injury causes cells to overproduce a protein known as beta - secretase (BACE).

If the approach also works with human cells, it could eventually lead to cell therapies for diseases like inherited leukodystrophies — disorders of the brain's white matter — and multiple sclerosis, as well as spinal cord injuries.

The spleen, which is 4 inches long and sits in the upper abdomen, acts as a reservoir of immune cells that speed to the site of heart injury after a heart attack to begin clearance of damaged tissue.

Embryonic stem cells are currently being trialled as a way to restore vision and treat spinal injury.

They hypothesized that expressing NeuroD1 protein into the reactive glial cells at the injury site might help to generate new neurons — just as it does in the hippocampus.

The study showed that a peripheral nerve injury in rats sends a message from damaged nerve cells to spinal cord immune cells known as glial cells, which normally act as «housekeepers» to clear out unwanted debris and microorganisms.

Massive blood transfusions — defined as transfusing at least 10 units of red blood cells within 24 hours — are given to patients experiencing severe blood loss, often in response to traumatic injuries but also in the context of procedures like cardiovascular surgery or liver transplantation and even in some non-surgical patients.

Although the research indicates it may someday be possible to regenerate neurons from the body's own cells to repair traumatic brain injury or spinal cord damage or to treat conditions such as Alzheimer's disease, the researchers stressed that it is too soon to know whether the neurons created in these initial studies resulted in any functional improvements, a goal for future research.

While it is generally accepted that MSC are mostly quiescent during postnatal life, MSCs in different niches can presumably differentiate into the specific cells of closely related niches during physiological turnover, injury or disease, as shown for other stem cell types (e.g., muscle satellite cells).

Right now, in our laboratories, our scientists are looking for ways to create insulin - producing cells in the laboratory, engineer blood vessels for heart bypass surgery and apply our regenerative medicine technologies to battlefield injuries through co-leading a $ 85 million federal grant, as well as many other novel research initiatives.