Sentences with phrase «as cell invasion»

The quantification of local contraction at the micron scale, including its directionality and speed, in correlation with other parameters such as cell invasion, local protein or gene expression, can provide useful information to study wound healing, organism development, and cancer metastasis.

Not exact matches

Casanova's experiments, published in Cell, point to an almost complete loss of DBR1 as the culprit, enabling brain stem virus invasion in all seven patients.

Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

Scientists have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

The groundbreaking study identified a protein, known as cadherin - 22, as a potential factor in cancer metastasis, or spread, and showed that hindering it decreased the adhesion and invasion rate of breast and brain cancer cells by up to 90 per cent.

A neuro - oncology research team at Dartmouth's Norris Cotton Cancer Center, led by the Director Mark A. Israel, MD with first author Gilbert J. Rahme, PhD, recently identified the transcription factor Id4 as a suppressor of tumor cell invasion in glioblastoma.

In preclinical experiments, the researchers disrupted AEG - 1 / Akt2 interaction through a process known as competitive binding and observed a reduction in GBM cell survival and invasion.

As a result, reduced abilities for cell growth, migration and invasion were found.

As Louis H. Miller, Head of Malaria Cell Biology Section at the National Institutes of Health notes, «The findings on the liver receptor EphA2 for malaria parasite sporozoite invasion of liver cells is a critically important advance and might allow us to devise new strategies to block parasite infection.»

When cancer cells split off from a tumor to seed deadly metastases, they are thought to travel as clusters or packs, a phenomenon known as collective invasion.

Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasCell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invascell invasion.

In addition, Sox9 acts also as key orchestrator of the extracellular matrix remodeling, cell adhesion and cytoskeleton dynamics required for tumor invasion.

The finding, reported by researchers at Harvard T.H. Chan School of Public Health, Northeastern University, and MIT, provides insights into organ formation in an embryo, healing of a wound, and even invasion of cells into surrounding tissue, as occurs in cancer.

Thus, in a panel of breast cancer samples, we identified tumor cells that did not form part of the bulk tumor mass, but instead were interspersed within the adjacent stroma — as if forming the forefront of cancer cell invasion.

Biocellion is being used to model a variety of biological system behaviors, such as biofilm formation and wrinkling, microbial growth dynamics in complex soil structure, brain tumor growth and invasion, formation of complex bacterial colonies, and changes in blood vessels and skin cells.

Simona thinks that this cell biological approach could help make sense of the heterogeneity of gliomas and improve our understanding of invasion overall: «These are key questions — we need to know how invasion is driven as it could have profound implications for therapy».

This appears to involve direct infection of Sertoli cells and germ cells which then results in a series of changes, such as cell death and invasion by immune cells, and pronounced inflammatory - like changes within the testes.

Overall, stem cell invasion of the biomaterial helped to regenerate kidney structures such as glomeruli (synaptopodin and CD31 positive) and tubules (cytokeratin and neprilysin positive) and promote recovery of function.

Data obtained on the effects of kahweol on endothelial cell invasion (as determined by a continuous fluorescent assay) clearly show that kahweol induces an anti-invasive effect in HUVEC in a dose - dependent manner (Figure 7).

However, the exact cytoskeletal strategy that the cell uses to cross the physical BM barrier depends on the physiological context and the physical environment, as observed by examining actin structures in invading cancer and immune cells, and in cells that invade during developmental processes such as angiogenesis and anchor cell invasion in Caenorhabditis elegans.

We use gut as model system to study cell migration in homeostasis, wound healing and cancer invasion (Fig. 1).

We propose that genes involved in cell migration and invasion, such as fascin1, could serve as novel targets for metastasis prevention.

Multiple studies have shown that fascin, through its role in formation of cellular protrusions such as filopodia and invadopodia, enhances cancer cell migration and invasion in vitro.

Tumor hypoxia is often linked to decreased survival in patients with breast cancer and has been shown to induce specific molecular changes in cells including changes that confer a more malignant phenotype such as increased proliferation (3), survival (4), invasion (5), and metastasis (6).

We examined the effect of loss of the gene on bacterial motility, adhesion and invasion of tissue culture cells and chicken colonisation, as well as the effect on the muropeptide profile of the peptidoglycan sacculus.

The vaccine encourages the body to create its own response to the «invasion» of the vaccine and stimulates the body's immune system, while traditional treatments, such as chemotherapy, kill white cells that defend the body and destroy infection.

A «WOW» maple syrup finding: Take this 2015 study reported in Oncology Reports: the researchers examined the effect of three grades of maple syrup (grades are based on the color of the syrup and ranges from light to darker with color being influenced by time of year and processing technique) on the proliferation, migration, and invasion of colorectal cancer (CRC) cells in order to investigate whether maple syrup is suitable as a phytomedicine for cancer treatment.

In addition, recent research reveals that maple syrup may be a potent phytomedicine with anti-cancer effects, as it has been demonstrated to selectively inhibit cancer cell proliferation and invasion (Yamamoto et al., 2015).

It decreases cell invasion, metastasis and epigenetic behavior of cancer cells as well.

They start as small defects in the tooth structure just under the gum line, and progress to painful invasion of the tooth by cells that gradually remove tooth structure and replace it with bone.

As the bacteria increase, your dog's mouth mobilizes cells to fight the invasion.

In the end, he's able to put a stop to the second alien invasion (the rest of that mess is all Gordon's to clean up), and the enigmatic dimensional traveller known as the G - Man dumps him into some sort of inter-dimensional holding cell until further notice.

Deployed to Camp Doha, Kuwait as an Imagery Specialist during the invasion of Iraq as part of a long - term intelligence fusion cell on the Baghdad team, using a real time GIS to make weekly geospatial reports of enemy activity (August 2002 - April 2003)