Sentences with phrase «as cell migration»

One is the actual repair process where there are unusual local responses such as cell migration, exaggerated replication / cell division, and varying forms of subsequent differentiation.

Are there defects in cytoskeletal organization in toddler mutant mesendoderm, which might affect cell division and cell numbers as well as cell migration?

Several labs are using the technology to study topics such as cell migration and neuroscience, he says.

Not exact matches

In the article, Dr. Margot Sunderland, author of the best - selling book What Every Parent Needs To Know, stated that leaving a child in a state of distress for a prolonged period without offering comfort affects them on a cellular level, specifically the «migration» of their cells as they get to where they need to be.

But when their functioning is altered, as the UCL researchers observed in tumor cells, the mitochondria can promote cell migration, thus leading to the formation of metastasis.

Much of the research into tumor cell migration, however, has represented the tissue as a solid gel.

As a result, reduced abilities for cell growth, migration and invasion were found.

While much remains to be learned about chemotaxis and cell migration, the authors hope that future races will be a fun - spirited approach to continue investigating cell motility and chemotaxis on a large - scale, as well as to provide further insight into relevant areas of research.

Recently published in the journal eLife and featured in a poster session at this year's American Association for Cancer Research (AACR) annual meeting, preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition (EMT).

Researchers found that histatin - 1 promotes angiogenesis, as well as cell adhesion and migration.

Cell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invasCell migration is highly coordinated and occurs in processes such as embryonic development, wound healing, the formation of new blood vessels, and tumour cell invascell invasion.

It's a «very important» and «very thorough» paper, says James Woods, a microbiologist at Midwestern University in Downers Grove,, Illinois, who has studied the migration of RASFs: «The fibroblasts that were active, they are usually thought of as a resident [i.e., nonmobile] cell.

By using fruit fly as a model system, Minna Poukkula working at the Institute of Biotechnology, University of Helsinki, has found out how actin - rich protrusions contribute to cell migration in animal tissues.

This finding comes as a surprise, considering that the average migration speed of the larger cell population does not change through multiple cycles.

The team explains that this is a step forward for research into cell migration mechanisms and that future applications will emerge as further investigation and studies are conducted.

«This shows that we can achieve robust and directional cell migration by mimicking the geometry of connective tissue as we find it in the body,» tells Olivier Pertz.

Additionally, Dr. Kissler's group narrows in on genes such as RGS1 that help to regulate cell migration.

This is the first time to visualize the real time event of asymmetric cell division, and we were able to see other events such as cell elongation of the zygote and migration of the nucleus.»

The laboratory is working in collaboration with Dr. Paula Foster to develop real - time cellular magnetic resonance imaging techniques as a means to track dendritic cell migration in vivo in humans.

But then Stainier and colleagues showed that the endoderm was also somehow responsible for the migration of the heart cell buds in the layer of cells above it, known as the mesoderm.

It has been observed that this pathway when is activated by upstream signaling cascades [such as growth factor receptors and G - protein coupled receptors (GPCRs)-RSB-, leads to cell proliferation, differentiation and migration.

In addition, the organs and tissues that possess high levels of SDF - 1, such as liver, lung, bone marrow, and lymph nodes, attract the migration of CXCR4 - expressing cancer cells [22].

Future studies of these cells are expected to shed light on developmental diseases such as autism and schizophrenia and malformations of brain development, including microcephaly, lissencephaly and neuronal migration disorders, they say, as well as age - related illnesses, such as Alzheimer's disease.

Our insight will substantially enhance our understanding of dynamic cell shape regulation for instance in the context of cell migration as in cancer metastasis or during morphogenesis.

Early in his career, he discovered that previously enigmatic support cells, known as radial glia, serve as guides for the migration of cortical neurons in the developing brain, and showed how this process is critical for the organization of the multi-layered structure of the cerebral cortex.

The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.

However, the morphology of the host inner retinal cells was well - preserved in the area of donor cell migration, as evident from the PKCα antibody staining, which labeled normal - appearing rod bipolar cell dendrites (upward arrows in Figure 6B).

Examples of these include cell proliferation, intracellular targeting, cell polarity, membrane traffic, cell migration, stem cell biology, chromatin regulation and function, differentiation, morphogenesis and biomechanics, and regeneration and cellular homeostasis, as well as developmental roles of genes, cellular structural dynamics, and signaling pathways.

Figure 6 shows the effects of 75 µM kahweol on endothelial cell migration, as determined by the «wound healing» assay, after 8 and 24 h of treatment.

They include its effects on endothelial cell «differentiation» to yield tubular - like structures, endothelial and tumor cell proliferation, apoptosis, and migration, as well as its effects on extracellular matrix remodelling enzyme activities of matrix metalloproteinase - 2 (MMP - 2) and urokinase - type plasminogen activator (uPA).

As an appropriate ECM substrate for cancer cell migration, we use nonpepsinized rat tail collagen I polymerized at room - temperature and fluorescently labeled to facilitate visualization using standard confocal microscopes.

During migration, cells overcome this problem either by creating a dense array of short - branched filaments as found in lamellipodia, or by bundling filaments as found in filopodia.

The Lauffenburger research group focuses on elucidating important aspects of receptor - mediated regulation of mammalian blood and tissue cell behavioral functions such as proliferation, adhesion, migration, differentiation, and death.

Uncoupling cell proliferation from apoptosis and possibly from cell migration can lead to pathologies such as cancer.

We use gut as model system to study cell migration in homeostasis, wound healing and cancer invasion (Fig. 1).

We propose that genes involved in cell migration and invasion, such as fascin1, could serve as novel targets for metastasis prevention.

Therefore, aRG cells serve both as neural stem cells and as tracks for neuronal migration, positioning them at the very centre of neocortical development.

Multiple studies have shown that fascin, through its role in formation of cellular protrusions such as filopodia and invadopodia, enhances cancer cell migration and invasion in vitro.

It is involved in the establishment of cell asymmetry, is particularly evident in large cells, such as eggs and neurons, and has key roles in cell fate decisions, cell migration, cell morphology, and polarised cell functions.

Cell migration assay was performed as described previously [22].

Fluorescence - based assays Fluorescent markers such as EGFP, YFP, mCherry and mTomato or fluorescent biosensors can be used to measure a variety of real - time cell - based activities, including, intracellular transport, protein signaling, receptor desensitization, migration, division, apoptosis, metabolism, differentiation, chemotaxis, transcription and translation.

(A) Treatment of MDA - MB - 231 cells with 0.3 μM flavopiridol (Flvp) significantly impairs cell migration as shown by the Transwell assay.

A «WOW» maple syrup finding: Take this 2015 study reported in Oncology Reports: the researchers examined the effect of three grades of maple syrup (grades are based on the color of the syrup and ranges from light to darker with color being influenced by time of year and processing technique) on the proliferation, migration, and invasion of colorectal cancer (CRC) cells in order to investigate whether maple syrup is suitable as a phytomedicine for cancer treatment.

That includes records of bird migration patterns and the dates that cherry trees bloom, as well as analyses of air bubbles sealed inside glacial ice cores and of the shells of foraminifera, single - celled sea creatures.