Another mutation, one in the FGF4 gene, gives the Corgi those disproportionately short, sturdy little legs, a condition known
as chondrodysplasia.
Not exact matches
Research interests include cartilage and joint diseases such
as osteoarthritis, rheumatoid arthritis, osteoporosis, bone tumors, and genetic bone diseases including
chondrodysplasia
Chondrodysplasia (often referred to
as CD) is the name given to a group of multisystem, metabolic disorders of skeletal development, primarily characterized by mild to moderate growth deficiency, short stature, and bilateral or asymmetric shortening and / or bowing of the legs.
Chondrodysplasia, a heritable skeletal disorder that has been incorporated into the phenotype of many dog breeds [13], predisposes English bulldogs to skeletal disorders such
as hip dysplasia, elbow dysplasia, luxating patella and shoulders, intervertebral disk disease, cruciate ligament rupture, hemivertebra, torsional pelvic deformity and problems with normal copulation and parturition [14, 15].
An earlier broadcast on the BBC spawned three independent reports identifying the English bulldog
as a breed in need of genetic intervention, presumably to breed away from the extremes of brachycephaly and
chondrodysplasia and increase genetic diversity.
Norwegian Elkhound
chondrodysplasia is similar to the other canine dwarfisms
as well
as to human spondylometaphyseal dysplasia; it is widespread in the breed, and may be associated with glycosuria (sugar in the blood), although in one study this was not found.