Sentences with phrase «as cisplatin»

IP5 worked as well as cisplatin in reducing the volumes of the tumors, the team reports today in Cancer Research.

«Given that pemetrexed combined with cisplatin may be less toxic than and as active as cisplatin plus paclitaxel and that it can be combined with bevacizumab, investigating the comparison of cisplatin - pemetrexed plus bevacizumab with cisplatin - paclitaxel plus bevacizumab would be the next appropriate step,» said Dr. Miller, who holds the Amy and Vernon E. Faulconer Distinguished Chair in Medical Science and the Dallas Foundation Chair in Gynecologic Oncology.

Not exact matches

As a result, the researchers then engineered a second nanostructure which was suffused with cisplatin.

The addition of necitumumab to gemcitabine and cisplatin chemotherapy improved overall survival and progression free survival by 21 % and 16 %, respectively, as compared to chemotherapy alone in patients whose tumours expressed the EGFR protein.

One of these, UJ3, is as effective as the industry - standard drug Cisplatin in killing cancer cells in laboratory tests done on human esophageal cancer, breast cancer and melanoma.

• Platinum - Resistant — these are patients whose disease recurred within six months of conventional chemotherapy (using the drugs cisplatin or carboplatin) and are generally less responsive to subsequent treatments and have not responded as well to PARP inhibitors.

In contrast, because of the high incidence of TP53 mutations in the HPV - inactive class, these tumors may be less responsive to the standard cisplatin chemotherapy and more sensitive to other chemotherapies such as dasatinib.»

In the current work we used adenoviral - type 5 (dE1 / E3)(Cytomegalovirus promoter) with human ABCA10 transgene (Ad - h - ABCA10) purchased from Vector Labs ® in order to investigate whether gene therapy can be used as a pre-treatment to enhance the efficiency of inhaled cisplatin.

The viral vector and aerosol cisplatin was safe as aerosol administration to the lung parenchyma as observed in Figure 1.

Aerosol administration was performed as follows, the residual cup was filled with 8mls of the cisplatin agent and the nebulisation time was 10 minutes (almost 1 ml / minute) as observed from our previous studies.14 The aerosol was delivered to the mice (one by one) within a nose only cage that has been previously presented.34 In the groups receiving the intratumoral cisplatin an insulin injection was used to deliver the 2mls of cisplatin within the tumor in different depths, however; a quantity of the drug when the injection was made superficially was lost since it was not accumulated.

The mice were divided into six groups as follows: a) control group (no therapy), b) only gene therapy inhalation, c) aerosol gene therapy plus aerosol cisplatin, d) aerosol cisplatin, e) intratumoral cispaltin and f) intratumoral cisplatin plus vector.

Short Research Communication The Factors Reducing Relative Dose Intensity of Cisplatin and Vinorelbine as Adjuvant Chemotherapy in Patients with Non-Small Cell Lung Cancer Ryo Inose, Katsuyuki Takahashi, Naruo Yoshimura, Tomoya Kawaguchi, Mitsutaka Takada, Katsuya Nagayama Oncomedicine 2018; 3: 9 - 14.

The only randomized study of adjuvant chemotherapy in mucosal melanoma demonstrated significantly increased relapse - free and overall survival in patients receiving temozolomide and cisplatin, as compared with interferon alfa - 2b or observation.

In this case, the cisplatin in the triple threat nanoparticle is delivered the instant the particle enters the cell, as it reacts to the presence of an antioxidant found in the cells called glutathione.

The team has tested its triple threat nanoparticles, containing drugs typically used to treat ovarian cancer (such as doxorubicin, cisplatin and camptothecin), against lab - grown ovarian cancer cells.

Indications for cisplatin beads include tumors removed with «thin margins» such as:

But cisplatin can not be used on cats as it is lethal to felines.

Medications: Some drugs, such as organophosphates (in older generation garden products), azathioprine, potassium bromide, L - asparaginase, cisplatin and thiazide diuretics, have been linked to pancreatitis.

It is also given as a kidney protectant to dogs receiving cisplatin chemotherapy.

The treatment results are almost identical for the 3 drugs; because cisplatin has to be given as an IV infusion, most oncologists are no longer using it.

High doses of Cisplatin or Piorxicam can be used in this regard, as per the veterinarian's prescription.