Sentences with phrase «as cytotoxicity»

We have also have adopted a number of lines of study into the regulation of cytokine production and effector cell responses such, as cytotoxicity, in the response of Vα14 iNKT cells to glycolipid antigens or IL - 12 from activated DCs.

Not exact matches

Some studies have demonstrated cytotoxicity of silver in wound repair and natural antimicrobials are being sought as alternative topical wound treatments to silver.

The in vitro boosted effector cells were washed once with HBSS and then resuspended in CRPMI and used as effector cells in the cytotoxicity and apoptosis assays (below).

Cytotoxicity was determined by the amount of 51Cr released by the target cells and the specific lysis was calculated as follows:

Antibody dependant cellular cytotoxicity (ADCC)- When antibodies coat an HIV - infected cell identifying it as something abnormal that needs to be killed.

In cytotoxicity assays employing PPAM, we found no significant differences of IC50 values between SCLC tumor cells, SCLC CTC lines which express the Wnt pathway and normal cells such as HEK293 (data not shown).

Cytotoxicity was enhanced by alterations of the regulators of apoptosis, such as Bcl2 / XIAP, in melanoma, lung cancer and adrenocortical carcinoma [9, 19, 21, 67].

They found that decreased presence of lymphatic vessels and reduced immune cytotoxicity were more strongly associated with the metastatic process than tumor - intrinsic factors such as chromosomal instability or cancer - associated mutations.

Treatment of the Gb3 - expressing gastric carcinoma cell line St3051 with STxB coupled to SN38, the active metabolite of the topoisomerase type I inhibitor irinotecan, resulted in > 100-fold increased cytotoxicity, as compared with irinotecan alone.

Cytotoxicity, improper localization, and decreased functionality are all possible consequences of FP aggregation, as Erik Snapp's blog post shows.

Furthermore, a genome - wide forward screen with Haplobank identified PLA2G16 as a host factor that is required for cytotoxicity by rhinoviruses, which cause the common cold.

A skin - lightening ingredient that works by inhibiting the activity of tyrosinase, by acting as a melanocyte cytotoxic inhibitor, and by increasing the cytotoxicity of melanocytes.

The systemic effects of stress include increased levels of stress hormones such as cortisol, a decline in certain aspects of immune system function such as natural killer cell cytotoxicity or secretory - IgA levels, and a disruption of gastrointestinal microflora balance.