Not exact matches
In the control arm,
dacarbazine was not used in compliance with the approval, however: Instead of administration in combination with another drug (doxorubicin),
dacarbazine was used
as monotherapy, and a different dosage was used in the beginning of the treatment.
The approval was based on a clinical trial comparing brentuximab vedotin plus conmbination chemotherapy (Adriamycin [doxorubicin], vinblastine and
dacarbazine, or AVD) vs a chemotherapy - only regimen commonly used to treat cHL (AVD plus bleomycin, also known
as ABVD).
Dacarbazine - based chemotherapy
as first - line treatment in noncutaneous metastatic melanoma: multicenter, retrospective analysis in Asia.