In contrast, because of the high incidence of TP53 mutations in the HPV - inactive class, these tumors may be less responsive to the standard cisplatin chemotherapy and more sensitive to other chemotherapies such
as dasatinib.»
Not exact matches
«Although TKIs such
as the first - generation TKI imatinib mesylate (IM) and the second - generation TKIs
dasatinib and nilotinib have markedly improved the prognosis of patients with chronic phase CML, a cure remains elusive.
Because
dasatinib is already cleared for clinical use, researchers hope that progress can be made more quickly towards trialling the drug in humans
as a treatment for DMD.
[68] Other KIT inhibitors, such
as sorafenib,
dasatinib, and sunitinib, have also been reported to have beneficial effects in mucosal melanomas harboring KIT mutations.
This discovery led him to evaluate second generation Abl kinase inhibitors, such
as the dual Src / Abl inhibitor
dasatinib, which received fast - track approval at the FDA in June 2006.