The latter is important to understand, as deamination (the process by which the amino group is removed) creates two products: Ammonia and a carbon skeleton (Acetyl CoA / acetoacetate or pyruvate).
The SureSeq mix increases the success and accuracy of hybridization - based NGS for FFPE samples by repairing damage such as nicks and gaps, oxidized bases, blocked 3» ends, and deamination of cytosine to uracil.