Although a relatively new stool test, fecal calprotectin is regularly used as indicator for inflammatory bowel disease IBD during treatment and
as diagnostic marker.
A type of antifungal antibody, called ASCA, is widely used
as a diagnostic marker since it is highly elevated in the blood of patients with several chronic diseases including Crohn's.
The company wanted to use
it as a diagnostic marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.
Not exact matches
There are some signs that we are seeing through research that can be used
as more early
diagnostic markers of autism.
At one extreme, some certifiers have abandoned using SIDS
as a cause - of - death explanation.7 At the other extreme, some certifiers will not classify a death
as suffocation in the absence of a pathologic
marker of asphyxia at autopsy (ie, pathologic findings
diagnostic of oronasal occlusion or chest compression8), even with strong evidence from the scene investigation that suggests a probable accidental suffocation.
If this discovery sample can be validated through replication these
markers may help
as a
diagnostic tool for psychiatrists treating mood disorders.
This protein also serves
as a docking site for
diagnostic markers and different drugs, such
as Valium.
Discovery improves understanding of the cause of allergic asthma and may serve
as an early
diagnostic marker.
This effort, which will enhance deCODE's proprietary gene and drug target discovery work and may provide genetic
markers for additional
diagnostic development, will leverage Illumina's Sentrix ® HumanHap BeadChips; Infinium ™ assay and LIMS (laboratory information management system);
as well
as analysis and visualization tools from Illumina's BeadStudio software.
Gata5 a potential
diagnostic marker for congenital heart disease The finding also suggests that gata5 could be a potential new
diagnostic marker for congenital heart defects,
as the researchers demonstrated that gata5 regulates the expression of a gene known
as nkx2.5 which, when mutated in humans, causes human congenital heart defects and disease.
Floryne Buishand, 30, from the Netherlands, is a postdoctoral researcher at the National Cancer Institute / NIH, Bethesda, USA, studies genomic changes associated with endocrine cancers with the ultimate goal of identifying novel
diagnostic and prognostic
markers,
as well
as novel therapeutic targets.
My short term goals for my postdoc are to identify novel
diagnostic and prognostic
markers,
as well
as novel therapeutic targets, leading to several high impact first authored publications.
The journal covers all aspects of surgical pathology, including classic
diagnostic pathology, prognosis - related diagnosis (tumor stages, prognosis
markers, such
as MIB - percentage, hormone receptors, etc.), and therapy - related findings.
deCODE is continuing its research on both phenotypes to identify and analyze the roles of these genes, with the aim of finding novel
diagnostic markers as well
as drug targets that can be used to combat asthma and allergies by going to the underlying causes of both conditions.
AMACR gene identified by Kimmel Cancer Center researchers
as a prevention and early
diagnostic marker for prostate cancer.
Finally, we ask whether the mechanical differences between normal and cancer cells can be used
as diagnostic or prognostic
markers of cancer progression.
ID1 gene identified by Kimmel Cancer Center scientists
as an early
diagnostic marker for melanoma.
(PSA is secreted from other female body tissues,
as well, and may be a possible
diagnostic marker for breast disease, among other conditions, just
as it is for prostate cancer in men.)
As markers flanking and successively closer to the disease gene are identified, the accuracy of a
diagnostic linkage test is improved, but even relatively distant
markers give some predictive information.