Sentences with phrase «as dynein»
The investigators showed that kinesin movement corresponds to traffic from the center of a nerve cell to its axonal tips — and a different motor in the squid's cytoplasm, which was subsequently identified as dynein, travels in the opposite direction.
http://www.laskerfoundation.org/
His research focuses on the development of high - precision, single - molecule methods to study the mechanism of action of macromolecular machines, such as dynein, telomerase, and Cas9.
Not exact matches
They found that this caused atoms in the entire protein to move in random directions when they performed their simulation of dynein floating in solution, as most conventional scientific simulations do.
Dynein switches between these different conformations as a result of the conversion of a molecule of ATP to ADP at a specific binding site on the protein, which releases energy as a chemical bond is broken.
«Not only is our physics - based simulation and animation system as good as other data - based modeling systems, it led to the new scientific insight that the limited motion of the dynein hinge focuses the energy released by ATP hydrolysis, which causes dynein's shape change and drives microtubule sliding and axoneme motion,» says Ingber.
«It's long been my hunch that the earliest events in left - right asymmetry involve a shunting [of signaling proteins such as ZIC3] to one side or the other, and it's certainly appealing to invoke dyneins and the cytoskeleton to help with that,» says Casey.
The team found changes in a gene encoding a previously unknown «dynein,» a protein that moves like a railroad locomotive along cytoskeletal fibers called microtubules, hauling other molecules as cargo.
He explained: «We set the dyneins running along their tracks and then we froze them in «mid-stride» by cooling them at about a million degrees a second, fast enough to prevent the water from forming ice crystals as it solidified.
Williams solved the structure of TcTex - 1, and then the complex of the dyenin intermediate chain and the light chains, showing that dynein light chains could not act as tethers.