Sentences with phrase «as embryo activity»

Not exact matches

As part of these ongoing research activities, the DNA of Dravet patients without SCN1A mutations was analyzed by trio exome sequencing, which searches across the active parts of the genome for de novo mutations that have arisen in these patients (de novo mutations are DNA copying errors that occur in the parents» gametes or in the fertilized egg or embryo, resulting in the afflicted family member being the first person in their family to have this genetic condition).

Niakan's group focused on a gene called OCT4 (also known as POU5F1), a master regulator of gene activity, which is important in mouse embryo development.

As was observed in W01A8.1 RNAi embryos, loss of W01A8.1 activity resulted in the formation of large LipidTox - positive structures (Figs. 4H and 4I) that were clearly bigger than droplets observed in control embryos using the same protocol (Figs. 4C and 4D).

With the first spontaneous movements taking place as early as 17 hours post-fertilization and swimming behavior occuring after 27 hours, zebrafish embryos prove to be a good model for the study of development of locomotor activity.