Mission: Raise public awareness about Polycystic Ovary Syndrome (PCOS) and help women with the condition overcome their symptoms and reduce their risk for life - threatening related diseases such
as endometrial cancer, type 2 diabetes and cardiovascular disease.
Amenorrhea can lead to serious health problems, such
as endometrial cancer or bone loss, so it should not be ignored.
Not exact matches
The authors suggest that HAND2 methylation «could be applied to triage women who present with postmenopausal bleeding (currently ~ 90 % of women who present with this symptom and are
cancer - free must undergo
endometrial biopsy for a definitive diagnosis) and could be further employed
as a test to early detect or even predict the risk for
endometrial cancer and response to preventative treatment.»
Using a new bioinformatics tool, they identified HAND2
as a differential methylation hotspot in
endometrial cancer.
«This finding,» Villanueva said «opens the door to developing new biomarkers and new therapeutic strategies exploiting these characteristics of exosomes in breast tumors, and other tumors such
as ovarian and
endometrial cancer among others.»
These so - called
endometrial organoids promise to shed light onto the processes that occur during the monthly menstrual cycle and open up the possibility of studying diseases of the uterus, such
as endometrial atrophy (thinning of the lining) or
cancer, in a lab culture system.
Importantly, the technique will also make it possible for researchers to grow organoids from diseased endometrium such
as in
endometrial atrophy or
cancer.
The study published in
Cancer Cell shows that exosomes from tumor cells of breast cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy
Cancer Cell shows that exosomes from tumor cells of breast
cancer (and other tumor types such as ovarian and endometrial) are different in size and composition than those of healthy
cancer (and other tumor types such
as ovarian and
endometrial) are different in size and composition than those of healthy cells.
Heeke says the study would be open to people whose tumors have evidence of HRD like those found in this study, which includes bladder, breast, cervix, liver and bile duct, colorectal,
endometrial, gastric / esophageal, head & neck, kidney, neuroendocrine, lung, ovarian, pancreas, prostate, sarcoma, and thyroid
cancers,
as well
as gastrointestinal stromal tumors, glioma, melanoma and unknown primary
cancers.
Evidence has linked sedentary time to increased risk of breast, colorectal, ovarian,
endometrial, and prostate
cancers as well
as weight gain, higher BMI, and obesity.
About one third of
cancer cases are estimated to be linked to dietary and other modifiable risk factors, especially for obesity - related
cancers such
as breast, colorectal, ovarian,
endometrial, kidney, gallbladder, esophageal, and pancreatic
cancers.
Although estrogen doses in oral contraceptives have decreased appreciably over the years, with pills in the 1960s typically containing more than double the estrogen dose of pills in the 1980s, the reduction in
endometrial cancer risk was at least
as great for women who used the pill during the 1980s
as for those who used it in earlier decades.
Use of oral contraceptives (usually referred to
as «the pill»), even for just a few years, gives substantial long - term protection against
endometrial (womb)
cancer, and the longer the pill is used the greater the reduction in risk, according to a detailed re-analysis of all the available evidence, published in The Lancet Oncology journal.
Coffee was also associated with a lower risk of several
cancers, including prostate,
endometrial, skin and liver
cancer,
as well
as type 2 diabetes, gallstones and gout.
The research evidence on breast, colorectal (bowel), pancreatic,
endometrial (womb), ovarian, prostate, liver, gallbladder, kidney, bladder, stomach and oesophageal
cancers has been updated
as part of our Continuous Update Project (CUP); these CUP reports replace the conclusions for these
cancers from the Second Expert Report.
Potential cardioprotection was based on generally supportive data on lipid levels in intermediate outcome clinical trials, trials in nonhuman primates, and a large body of observational studies suggesting a 40 % to 50 % reduction in risk among users of either estrogen alone or, less frequently, combined estrogen and progestin.2 - 5 Hip fracture was designated
as a secondary outcome, supported by observational data
as well
as clinical trials showing benefit for bone mineral density.6, 7 Invasive breast
cancer was designated
as a primary adverse outcome based on observational data.3, 8 Additional clinical outcomes chosen
as secondary outcomes that may plausibly be affected by hormone therapy include other cardiovascular diseases;
endometrial, colorectal, and other
cancers; and other fractures.3, 6,9
The DNA repair deficiency, called homologous recombination deficiency, or HRD, has previously been studied in only a few
cancers, but
as researchers at Georgetown Lombardi Comprehensive
Cancer Center report, HRD can be found in all of the cancer types the researchers studied, including prostate, breast, pancreatic, and endometrial cancers as well as two of the more deadly types: ovarian cancer and glioma, a type of brain c
Cancer Center report, HRD can be found in all of the
cancer types the researchers studied, including prostate, breast, pancreatic, and endometrial cancers as well as two of the more deadly types: ovarian cancer and glioma, a type of brain c
cancer types the researchers studied, including prostate, breast, pancreatic, and
endometrial cancers as well
as two of the more deadly types: ovarian
cancer and glioma, a type of brain c
cancer and glioma, a type of brain
cancercancer.
Currently, the CDK9 inhibitor flavopiridol is being evaluated in several phase I and II clinical trials for its anti-
cancer effects either
as a single agent or in combination with other drugs in treatment of esophageal
cancer, B - cell chronic lymphocytic leukemia,
endometrial carcinoma, recurrent / metastatic squamous cell carcinoma and most relevantly, previously treated locally advanced or metastatic breast
cancer (http://www.cancernetwork.com/review-article/current-clinical-trials-flavopiridol/page/0/2).
Isoflavones can also regulate blood lipid levels
as well
as prevent certain types of
cancer such
as breast, ovarian,
endometrial, and prostate
cancers.
Excessive weight gain can also be a reason for different forms of
cancers, such
as breast, gall bladder, prostrate, kidney, colon and
endometrial cancer.
When you reverse your estrogen dominance, you clear the path toward a healthy weight and reduce the incidence of estrogen - dominant conditions such
as diabetes, metabolic syndrome, and certain forms of breast, ovarian, and
endometrial cancer.
As you probably know, BCPs are prescribed, mostly off label, for acne, hirsutism, painful periods (dysmenorrhea, including endometriosis), irregular menstruation, heavy periods (menorrhagia), reduction in risk of ovarian and
endometrial cancers, and improvement in premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD).
As discussed in the video, there is also some evidence that soy may prevent certain hormone - dependent
cancers, including breast
cancer,
endometrial cancer, and prostate
cancer.
That can lead to estrogen overload — and that can lead downstream to hypothyroidism,
as well
as breast,
endometrial, and cervical
cancers.
The association between caffeine and hormones is of interest, because persistent elevation or insufficiency of reproductive hormones during the premenopausal years may not only contribute in the long term to the etiology of certain diseases, such
as breast,
endometrial, and ovarian
cancers (11 — 14), but may also affect ovulatory function in the short term (15, 16).
To see whether the test works, the researchers gathered samples from 1,658 women, including 656 with
endometrial or ovarian
cancers,
as well
as just over 1,000 healthy women for the control group.
As for
endometrial cancers — tumors of the uterine lining — the benefit was even greater for women with less healthy lifestyle habits.
According to the study from the U.S. National
Cancer Institute, these trends were also observed for endometrial cancer as
Cancer Institute, these trends were also observed for
endometrial cancer as
cancer as well.
In Berlin, a group of researchers trained some dogs to detect the presence of various types of
cancer, including ovarian
cancer, bowel
cancer (which apparently smells different from both
endometrial cancer and cervical
cancer),
as well
as bladder
cancer, skin
cancer, lung
cancer and prostate
cancer.