Sentences with phrase «as epistasis»

Such interactions, when the effect of a mutation is dependent on another, are known as epistasis.

Rather, he says, the most likely explanation is a phenomenon known as epistasis, where genes can interact so as to greatly multiply an effect.

Not exact matches

«This is important in the field because epistasis has been proposed as a source of «missing heritability,»» said the study's lead author, Joanna Thornycroft, a former graduate student at the Whitehead Institute for Biomedical Research, now at Wellcome Sanger Institute.

Epistasis makes fitness trajectories unpredictable in yeast, even as they converge upon the same biological pathway.

Schizophrenia researcher Daniel Weinberger of the National Institute of Mental Health in Bethesda agrees that the paper adds to evidence that epistasis — which has been shown in model organisms such as yeast but difficult to prove in humans — is «robust and ubiquitous.»

This discovery approach greatly enhances the future potential of epistasis analysis for systems biology, and can complement genome - wide association studies as a means of formulating hypotheses for targeted experimental work.