Sentences with phrase «as first line treatment»

However, more research is required before STPP is adopted as a first line treatment for the disorders covered in their review.

Selective serotonin reuptake inhibitors (SSRIs) as first line treatment for depression were more cost effective than tricyclic antidepressants (TCAs) alone, but less cost effective than TCAs as first line treatment with SSRIs for dropouts.

It is recommended as the first line treatment of T2D in all cases.

Highly active antiretroviral therapy, or HAART, typically combines three antiretroviral drugs (ARVs) as a first line treatment for HIV infection.

Not exact matches

An important trigger this year will be the outcome of a study where Darzalex is being tested as first - line treatment in combination with Celgene Corp's Revlimid.

For numerous medical conditions, such as obesity, diabetes, insomnia, and chronic pain, the «first - line» and most effective treatments are often behavioral.

As with any non-traumatic knee injury, if your physician suspects you have plica syndrome the first line of treatment is rest, activity modification, anti-inflammatory medications, and physical therapy to decrease inflammation around the plica.

In the case of mild postnatal depression, therapies will always be recommended as a first line of treatment as long as there are no previous mental health problems or conditions.

Tricyclics may also cause troublesome effects, and that is why doctors shy away from using them as a first - line treatment.

The first - line designation means that some patients will have access to the drug without first having to receive other treatments such as chemotherapy.

«Our results do not support the addition of corticosteroid to antihistamines as a first - line treatment of uncomplicated acute hives.

These findings informed new WHO guidelines reinstating artesunate plus mefloquine as the first - line ACT in Cambodia where dihydroartemisinin - piperaquine treatment has failed.

Demand for this plant - based version of the drug has been high since 2005 when the World Health Organization officially recommended it, combined with other anti-malarial drugs, as a first - line treatment for malaria.

Lithium is among the most effective therapies for BD, and remains the first - line treatment even as other mood stabilizing drugs have become available.

«However, we believe our study findings, in combination with the previous literature and our clinical experience, are sufficient to support catheter ablation as first - line treatment for AFL,» Marcus said.

«It is often prescribed as the first - line treatment for bipolar disorder.

«This is why we're diligently working to employ several strategies that we hope will lead us to reaching our ultimate goal of developing the best therapy possible — a therapy that can be given to patients as a first line of defense, greatly reducing the side effects of cancer treatment and leading to a cure.»

All patients received standard first - line treatment of FOLFIRI plus cetuximab until disease progression or unacceptable toxicity, as previously reported (Ciardiello et al, Annals of Oncology 2014).

The drug was approved by the FDA as a combination first - line therapy for postmenopausal women with ER + / HER2 - breast cancer, as initial endocrine - based treatment for their metastatic disease.

The goals of Cohort B, for which survival data are not yet complete, were, primarily, to prove pembrolizumab's safety and, secondarily, to explore its efficacy as a first - line treatment.

Carlos A. Morillo, M.D., F.R.C.P.C., of McMaster University, Hamilton, Canada, and colleagues compared ablation to drug treatment as first - line therapy in patients with paroxysmal AF who had not previously received treatment.

«With a key challenge being that resistance to drugs is spreading faster than new drugs are being developed and approved,» they suggest that «the use of encapsulated, nanobody - targeted drugs as described here has the potential to reverse resistance to many first - line treatments.»

Yet, until now, the UK's National Institute for Health and Clinical Excellence (NICE) has said there is insufficient evidence to recommend behavioural activation as a first - line treatment in clinical guidelines, and has called for more robust research to investigate the benefits.

Norepinephrine is recommended as the first - line vasopressor (a drug that constricts [narrows] blood vessels, increasing blood pressure) for treatment of hypotension (abnormally low blood pressure) due to septic shock.

«Because PGAs are a first line of treatment for glaucoma, these results provide physicians with one reason to reconsider when they should be added in new patients, particularly those where the aim is to prevent glaucoma such as in ocular hypertension patients or glaucoma suspects,» Dr. Pasquale said.

It is estimated that up to 10,000 Australians with severe depression and who have not responded to first line treatments, such as medication, could benefit from the new treatment.

Therefore, it may benefit patients both as a first - line and second - or later - line treatment, by producing a durable clinical benefit and with a reduced toxicity profile compared to current EGFR inhibitor therapies.

Researchers sought to learn whether the drug could be beneficial as a first - line treatment.

Though behavioral parent training is known to have positive results for children with ADHD, fewer parents and mental health and medical practitioners know about it than medication prescribed for ADHD, which can come with side effects and is not recommended as a first - line treatment for preschool - age children, DuPaul said.

• Subject has received prior treatment with ASP2215 or other FLT3 inhibitors (with the exception of sorafenib and midostaurin used in first - line therapy regimen as part of induction, consolidation, and / or maintenance).

The FDA granted accelerated approval to avelumab (Bavencio, EMD Serono, Inc.), a checkpoint immunotherapy that targets the PD - 1 pathway, as a first - line treatment for a rare form of skin cancer called Merkel cell carcinoma (MCC).

Tanyi said he is eager to explore whether the dendritic - cell vaccine might also be used as a first - line treatment for women who are newly diagnosed with ovarian cancer.

Subject must have achieved a CR / CRi / CRp (criteria as defined by [Cheson et al, 2003], see Section 5.3) with first line treatment and has hematologic relapse.

Dacarbazine - based chemotherapy as first - line treatment in noncutaneous metastatic melanoma: multicenter, retrospective analysis in Asia.

One leukemia patient but not another may be eligible for a bone marrow transplantation as a first line of treatment — a harsh, costly, but potentially curative treatment.

In 2015 and 2016, the FDA expanded its approval of pembrolizumab and nivolumab as first - line treatments for unresectable or metastatic melanoma, regardless of mutational status.

Based primarily on clinical trials led by Arjun V. Balar, MD, assistant professor of medicine and director of the Genitourinary Medical Oncology Program, the FDA approved atezolizumab (Tecentriq ®) and pembrolizumab (Keytruda ®) as first - line treatments for these particularly frail patients with advanced bladder cancer in early 2017.

Led by Leena Gandhi, MD, PhD, associate professor of medicine and director of thoracic medical oncology, researchers from the KEYNOTE - 021 study demonstrated for the first time that combining an immune checkpoint inhibitor — in this case, pembrolizumab — with a platinum - doublet chemotherapy regimen might be more effective than chemotherapy alone as first - line treatment for advanced, non-squamous NSCLC.

«As a result, now when most patients are identified for the first time with leakage in the center of their retina with associated loss of vision, the first line of treatment is a VEGF inhibitor therapy,» he said.

Metronidazole and vancomycin remain as first - line treatment options for these isolates.

While researchers don't recommend omega - 3s as a first - line treatment for anyone with major depression or bipolar disorder, emerging research suggests it may be effective for people with mild depression or as an adjuvant to medication.

First - line treatments include rest (if you're a runner, switch to a low - impact activity such as swimming), icing for 20 minutes several times a day, and OTC anti-inflammatories such as ibuprofen.

Noting the link between obesity and high blood pressure, the academy pointed out that lifestyle changes — such as diet and exercise — are the first - line treatment for high blood pressure.

Despite the limited evidence for the use of antidepressants in this population, some doctors have begun using the drugs — especially sertraline — as a first - line treatment, the researchers say.

Also known as talk therapy or counseling, psychotherapy may be the first line of treatment for people with mild depression.

Retrospective studies have shown this diet to be an effective and well - tolerated treatment for infantile spasms (4, 5, 6, 7, 8), with one study reporting significant spasm improvements and less side effects when the diet was used as an alternative first - line therapy to ACTH (9).

Esselstyn had people on drugs at first as * part * of a treatment for desperate people at the end of their line.

The first - line of treatment for migraine headaches by the medical establishment is pain medication such as ibuprofen, acetaminophen or any other drug classified as a non-steroidal anti-inflammatory drug (NSAID).

Birth control pills have long been demonstrated as a first - line treatment option for women with Polycystic Ovary Syndrome (PCOS) who suffer from painful or irregular or absent periods.Some women may take Oral contraceptive pills (OCPs) to help lower androgen levels and improve unwanted dermatological symptoms.

Because of its numerous benefits, MYO should be considered as a first - line approach in the treatment of all women PCOS, not just those looking to get pregnant.