Sentences with phrase «as gene sequencing»

Clinical Molecular Geneticists are certified to perform and interpret molecular analyses such as gene sequencing.

Some of these residues, also known as gene sequences, are very similar to those from known animals, Rogers says.

Not exact matches

Speaking about the film recently in Los Angeles, Cera — who in this film, takes some refreshingly bold steps away from his usual one - note nerd persona — and co - writer / director Edgar Wright (who also did the zany cult classics Shaun of the Dead and Hot Fuzz) discussed the meaning of the film, the stretching Cera had to go through for the role, and the way in which the film's hyperkinetic action sequences are really just the same as the dance scenes in Grease or a Gene Kelly movie.

It is a term used by people grasping at straws to continue dismissing evolution even as the evidence builds faster than ever at the gene sequencing level (ie, most of you agree that drug resistant bacteria have evolved but the term MACRO evolution is misused intentionally so you could continue to dismiss science to save faith; pun intended).

Using a gene - sequencing technique known as whole - exome sequencing that targets only the DNA that encodes proteins, the researchers cataloged virtually every significant DNA variant in three families in which the condition is common.

These changes, known as epigenetic modifications, control the activity of our genes without changing the actual DNA sequence.

Analysis of physical characteristics in three - dimensionally preserved Fukangichthys skulls, as well as an examination of DNA sequences from 12 genes, revealed that scanilepiforms are actually ancient cousins of polypterids.

The estimate of the number of human genes has been repeatedly revised down from initial predictions of 100,000 or more as genome sequence quality and gene finding methods have improved, and could continue to drop further.

When researchers sequenced the sponge's genome in 2010, they found genes that help individual cells cooperate as a group: how to divide, send signals to one another, and distinguish between friends and outsiders.

I had zero computer experience; in fact, I could barely type, but a postdoc in the lab helped me do a BLAST search using my gene's protein sequence as a query.

You need the oligonucleotides to stitch genes together, and as far as I know, most companies will check the order if the sequence represents that of a dangerous virus.»

Data published by the International Human Genome Sequencing Consortium indicate that somewhere between 113 and 223 genes present in bacteria and in the human genome are absent in well - studied organisms — such as the yeast Saccharomyces cerevisiae, the fruit fly Drosophila melanogaster and the nematode Caenorhabditis elegans — that lie in between those two evolutionary extremes.

However, the results of more recent phylogenetic analyses, derived from comparisons between sequences of specific genes and of whole genomes, seemed to point to Ctenophora as the first group that parted company with the lineage from which the rest of the animal kingdom (including sponges) evolved.

The idea of «reversal drives,» which would overwrite mutated genes with the original sequence, often arises as a promising solution to gene drives gone wild.

Within the PTO, controversy has continued as to whether ESTs themselves are patentable, to say nothing of whether the claims can and will cover the full - length gene sequences.

As for the identities of Mendel's other four genes, Weeden says he expects them to be revealed in the next few years as more plant genomes give up their sequenceAs for the identities of Mendel's other four genes, Weeden says he expects them to be revealed in the next few years as more plant genomes give up their sequenceas more plant genomes give up their sequences.

Using a combination of old - fashioned clinical observation and modern biochemical analysis, he has shown that a person's appetite and their eating behavior can be linked to specific genes — and that even a tiny defect such as the absence of a single nucleic acid in a sequence of DNA can lead to runaway weight gain.

Using a technique known as single - cell RNA sequencing, the team explored more than 65,000 individual cells that exist under normal or inflammatory conditions, looking for genes that were more active in one state or subpopulation versus another.

No one is arguing that Lamarck got everything right, but over the past decade it has become increasingly clear that environmental factors, such as diet or stress, can have biological consequences that are transmitted to offspring without a single change to gene sequences taking place.

What if you could trace brain circuits as if you were sequencing genes?

The sequences provide researchers access to 96 percent of all peanut genes and provide the DNA map needed to more quickly identify and genetically tag genes that confer desirable traits, such as drought - and disease - resistance.

They processed data relating to genetics, including DNA sequences, and to gene expression, as well as epigenetic features — chemical reactions that influence genome functioning and hence phenotype by activating and deactivating genes.

Does sequencing the genes of animals such as the mouse and the dog help us understand ourselves?

Collaboratively, the research team sequenced the DNA that encodes the genes as well as the RNA from the insect at different developmental stages, to identify when different genes are expressed and in which tissues and organs.

Trent and others says that the same mechanism might be at work in genes linked to other cancers, such as breast and prostate cancer, which have been found to contain similar «harmless» sequence variations.

They identified 60 genes that exhibited convergent evolution in CAM species, including convergent daytime and nighttime gene expression changes in 54 genes, as well as protein sequence convergence in six genes.

As the cost of gene sequencing drops, DNA being sequenced for one purpose may yield many other secrets, such as the risk of certain cancers and Alzheimer's diseasAs the cost of gene sequencing drops, DNA being sequenced for one purpose may yield many other secrets, such as the risk of certain cancers and Alzheimer's diseasas the risk of certain cancers and Alzheimer's disease.

Gene sequencing confirmed that the animals bore an analogous DNA mutation to the one seen in humans, which removes a large chunk of the BIN1 gene, known as exonGene sequencing confirmed that the animals bore an analogous DNA mutation to the one seen in humans, which removes a large chunk of the BIN1 gene, known as exongene, known as exon 11.

In the case of β - ionone, the smell associated with violets, McRae and colleagues managed to pinpoint the exact mutation (a change in the DNA sequence) in the odorant receptor gene OR5A1 that underlies the sensitivity to smell the compound and to perceive it as a floral note — people who are less good at smelling β - ionone also describe the smell differently, as sour or pungent, and are less likely to find it pleasant.

Medical researchers at the Centre for Personalised Immunology, based at the John Curtin School of Medical Research (JCSMR), sequenced the genes of a young girl who suffered a stroke when she was four as a result of her lupus.

In this study that used deep DNA sequencing of bacterial specific genes, the guts of both males and females exposed to lead had all of the similar complexity in microbiota as those not exposed.

Berninger and others have previously shown that Sox2, Ascl1, and other transcription factors — proteins that bind to specific DNA sequences to control the activity of genes — can induce the nonneuronal «support cells» known as glia to turn into neurons.

They enable molecular biologists and geneticists to selectively chop DNA into pieces, which can then be assembled into new versions of the gene, inserted into the genomes of other organisms, or sequenced as part of an effort to map an organism's genetic material.

Our RNA sequencing analysis of NAFLD - HCC samples revealed squalene epoxidase (SQLE) as the top outlier metabolic gene overexpressed in NAFLD - HCC patients.

To deliver the healthy gene, the team inserted it into an engineered virus called adeno - associated virus 1, or AAV1, together with a promoter — a genetic sequence that turns the gene on only in certain sensory cells of the inner ear known as hair cells.

Large - scale methods of probing samples, such as DNA sequencing, microarrays, and automated gene - function studies, are filling new databases to the brim.

It could also be relevant to clinical applications — it treats sequence uniqueness as a high priority and thus minimises the risk of potentially unwanted gene modifications, which must be avoided at all costs in gene therapy,» says Graf.

Nucleic acid and protein sequences, as well as three - dimensional structures of proteins, are frequently the objects of study, but gene expression as well as the simulation of pathways and biochemical networks are attracting more and more attention.

Genome sequencing revealed that the isolated B. pumilus contained three unique gene clusters for the production of antimicrobial peptide compounds known as bacteriocins.

As large - scale genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced geneAs large - scale genome sequencing projects, such as the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced geneas the Human Genome Project, near completion, the research community's focus is shifting toward efforts to determine functional information about these sequenced genes.

Both studies relied on a popular lab organism known as C. elegans, a nearly microscopic nematode that is fast growing, translucent and has a sequenced genome showing that nearly half its genes are closely related to corresponding human genes.

As when he worked on the human genome, Venter is relying on a radical technique called shotgun sequencing: He chops up vast amounts of DNA into tiny pieces and then uses sophisticated computer analyzers to piece them back together into intelligible genes and chromosomes.

These tags are detected and measured using a sensitive DNA analysis technique known as massive, parallel sequencing, providing a quantitative readout of the gene's activity levels.

«Changes in genes» regulation — not in the DNA sequence of genes themselves — were the driving force behind successful metastases in our experiments, and, as far as we know, this is the first genomewide experimental evidence for this phenomenon.»

Computational genomics includes: bio-sequence analysis, gene expression data analysis, phylogenetic analysis, and more specifically pattern recognition and analysis problems such as gene finding, motif finding, gene function prediction, fusion of sequence and expression information, and evolutionary models.

When population geneticist Andrea Manica and graduate student Marcos Gallego Llorente at the University of Cambridge in the United Kingdom analyzed the sequence, they found that the Mota man had brown eyes and dark skin, as well as three gene variants associated with adaptation to high altitudes; some peaks in the highlands reach 4500 meters, as high as the Matterhorn.

Dissatisfied with such wobble in the basic gears of the molecular clock, evolutionary biologists Sudhir Kumar and Sankar Subramanian decided to establish a more reliable mammalian mutation rate based on as many gene sequences as possible.

Our genes can be thought of as packets of information written in sequences of DNA bases, which encode proteins that perform the functions necessary for life.

As scientists began to sequence human genes in the 1990s, sorting out the cellular locations of each gene's proteins became a priority, says Mathias Uhlén, a microbiologist at the Royal Institute of Technology in Stockholm, Sweden, and director of the Protein Atlas effort.

Many of these repeats, including some genes, appear as back - to - back series of the same repeated sequence or as long palindromes which, like the word «racecar,» read the same forward and backward.