Sentences with phrase «as genes involved»

The enzymes involved in glutathione production as well as the genes involved in producing enzymes that allow the body to manufacture and produce glutathione can be tested.

«Glutathione deficiency is found in nearly all very ill patients... Glutathione can only be produced if both the methylation and sulfation cycles are running smoothly... The enzymes involved in glutathione production as well as the genes involved in producing enzymes that allow the body to manufacture and produce glutathione can be tested.»

«Evidence indicates that the fatty and inflamed liver expresses several pro-inflammatory and procoagulant factors, as well as genes involved in accelerated atherogenesis,» explained lead investigator Raluca Pais, MD, PhD, of the Pierre and Marie Curie University, INSERM, and the CDR Saint Antoine, Institute of Cardiometabolism and Nutrition (ICAN), Paris, France.

The teams are yet to identify every gene contained within this supergene region, but have so far found a gene involved in colouring, which could explain differences in plumage, as well as genes involved in processing sex hormones.

Not exact matches

RNA interference involves synthesizing short strands of RNA that will turn off harmful genes, such as the ones that allow viruses to spread.

It's also working in Beijing on new technology in genome editing; unlike GMO technology, it doesn't involve inserting a gene from another species, such as a bacterium, into a plant.

But, as journalist Steve Connor reports, the reference to editing was intentional: «Scientists have used the genome - editing technology to cure adult laboratory mice of an inherited liver disease by correcting a single «letter» of the genetic alphabet which had been mutated in a vital gene involved in liver metabolism.»

The newer process of genetic engineering, which involves inserting genes from unrelated species into a plant's genome to add desirable traits, has been used in crops such as corn, soy, and potatoes.

We confirmed this gene — environment interaction in two birth cohorts, and we ruled out alternative explanations of the finding involving gene — exposure correlation, intrauterine growth, social class, and maternal cognitive ability, as well as maternal genotype effects on breastfeeding and breast milk.

«We think that the garter snake's evolved resistance to the newt's toxin can be used as a model for understanding complex adaptations that involve more than one gene,» McGlothlin said.

A number of individual genes have been linked to suicide, such as those involved in the brain's response to mood - lifting serotonin, and a signalling molecule called brain - derived neurotrophic factor (BDNF), which regulates the brain's response to stress.

An exciting prospect for the future involves the recovery of an entire system of clock - regulated genes in organisms such as fruit flies and mice.

Interestingly, as many as nine of the genes have been previously associated with some vascular disease and four more are known to be involved in the regulation of vascular tone, supporting the importance of blood vessels in migraine attacks.

Messenger RNA (mRNA) serves as an important intermediary during gene expression, by relating the genetic information of DNA to the molecular mechanisms involved in manufacturing proteins.

What's more, the gene codes for a chemical receptor involved in many brain functions, such as learning and memory, so the gene might also be involved in behavioral disorders.

The scientists found changes in the domestic cat's genes that other studies have shown are involved in behaviors such as memory, fear and reward - seeking.

Scientists have shifted from studying single molecules to investigating large complexes of interacting biological macromolecules involved in processes such as metabolic pathways, gene expression, and development of disease.

The researchers have compared various processes involved in gene expression, such as gene transcription and chromatin modification, and have repeated this in different tissues and cell types from both humans and mice.

Although the whole drive to understand the molecular basis of beer production involves modern tools that are used in biotechnology, such as real - time polymerase chain reaction (PCR), gene chips, proteomics, mass spectrometers, and so forth, genetic manipulation is not acceptable in any form — not in any of the raw materials or the yeast.

They add that other genes in the region of the genome around Gp - 9 are probably involved in regulating fire ant social organization as well.

Injecting donor cytoplasm into an egg involves transferring mitochondria and their genes as well.

The team had expected to find changes in many genes involved in serotonin signaling, a process targeted by some popular antidepressants such as Prozac.

They found numerous genes activated in the XYL regulon - controlled yeast that upregulated pathways involved in growth, such as cell wall maintenance, cell division, mitochondrial biogenesis and adenosine triphosphate (ATP) production.

Indeed, after Siddle added a squirt of interferon - gamma — a chemical messenger that activates numerous genes involved in producing MHC antigens — to cells cultured from devil tumors, the MHC genes functioned normally again, and the tumor cells» identity cards showed up, plain as day.

As a courtesy, Vogelstein, whose lab had already uncovered a fistful of genes involved in the disease, offered to test the 39 - year - old man for known mutations.

Even when the genes are more fully understood, scientists will have to find the right host organism to express the genes, optimize that expression and try to get them to produce as much of the oil as possible — all of which involves a lot of basic research and time, he said.

Studies seeking subtle signs of selection in the DNA of humans and other primates have identified dozens of genes, in particular those involved in host - pathogen interactions, reproduction, sensory systems such as olfaction and taste, and more.

Ongoing studies by investigators across the country, including Drs. Abraham Palmer and James MacKillop, who also participated in the conference, involve analysis of DNA and questionnaire responses from as many as 25,000 human subjects in order to identify specific genes involved in delay discounting.

The findings highlight specific sets of genes and the brain cells they affect as being involved in regulating anxiety.

Today theories of links between genetics and behavior have led to what Rafter calls ««new» or «liberal» eugenics» that involves the elimination of «bad» genes by choice, such as the abortion of fetuses that test positive for mental retardation.

How could notifications such as this be effectively carried out given that thousands of genes are involved in hundreds of diseases across millions of patients?

Those findings — published this week in Current Biology — suggest that the gene, known as FOXP2 is involved in learning the muscle movements necessary for speech, explains co-author Simon Fisher, a professor of molecular neuroscience at Oxford's Wellcome Trust Center for Human Genetics.

Eyes Genes involved in eye development might help the butterflies detect fine changes in the sun's position, as well as patterns of polarized light.

Others are involved in conditions that tend to occur alongside ASD, such as psychiatric disorders and epilepsy, and interestingly, some of the genes are also involved in cancer.

The function of these genes were involved in molecular maintenance strategies, such as DNA repair, chromosomal maintenance, immune response and programmed cell death The authors argue that the «slower rate of change in these functions is consistent with increased constraint on somatic cell maintenance as would be required in these relatively long - lived and large - bodied mammals, illustrated by the additional large and long - lived species with slower rates in these genes (e.g. double - strand break repair gene XRCC4 is also highly constrained in elephant.»

As epigenetic changes to genes can be profound and durable, it is entirely likely they are involved in human disease.

These traits contrast with previous biocontainment strategies involving synthetic organisms and energy sources, requiring hundreds of gene edits, awful lots of money and time, and which are so specialized as to make them impractical.

As an example, the current study identified and provided insight into the function of several genes, not previously known to be involved in the taste system, related to cell motility.

«The database is a precious resource for the research community studying plant - microbe interactions as it is an unbiased way to identify potentially interesting genes involved in interaction with a plant — including many totally novel genes.

«For instance, the gene YWHAZ, involved in neuronal migration and plasticity, is associated with other diseases such as schizophrenia,» explains Cormand.

With chronically infected mice as their model, the researchers used a new technology called ATAC - seq to map the regulatory regions of the genome — the sections of DNA involved in switching genes on and off — in the animals» exhausted and functional CD8 + T cells.

As I had mentioned earlier, it's a very, very complicated process involving hundreds of proteins, a thousand or so genes, and we really need to delineate exactly all of the changes that are occurring.

Other researchers soon discovered that other genes were similarly involved in this paternal - maternal conflict — and that paternal genes pushed for growth, as Haig theorized.

By studying bizarre mutants such as flies with legs in place of antennae, we have identified many of the genes involved in development.

Now researchers have identified a mutation in the human ATP4a gene that is involved in the gastric acid secretion regulation and has been identified as responsible of an aggressive form of inherited, early - onset gastric NET.

The studied gene is involved in the circadian system, which has previously been shown to be implicated in mental disorders such as bipolar disorder, which intriguingly is comorbid with migraine.

But as you said, as an individual eats a high - fat diet or is exposed to other types of environmental exposures, the ability of the liver to adapt involves turning on and turning off certain liver genes to control the liver's activity, and that's mediated through these epigenetic mechanisms that modify the activity of established liver genes.

When these birds sing, the activity of a master gene called FoxP2 declines in a key region of the brain involved in vocal control known as Area X.

And we now know that it is the same epigenetic mechanisms that occur in brain as occur in liver, just involving, only the specifics differ — brain genes in brain, liver genes in liver.

In 1991, Robertson and her colleagues reported an unusual discovery involving a gene called Igf2, which is responsible for producing a protein known as insulin - like growth factor II (IGF - 2), important for the growth of many kinds of tissue in the developing fetus.