The research identifies a potential characteristic for predicting outcome in a deadly form of brain cancer
known as glioblastoma multiforme.
Treatments that rely on modified polioviruses to target tumors
such as glioblastomas are already in clinical trials in the United States, and there's a modified herpesvirus approved by the U.S. Food and Drug Administration for treating melanoma.
Researchers have used low - intensity, intermediate - frequency electric fields to combat an aggressive brain cancer known
as glioblastoma multiforme (GBM).
«The immediate clinical implication is that a group of patients with tumors previously categorized as lower grade should actually be
treated as glioblastoma patients and receive that standard of care — temozolomide chemotherapy and irradiation,» said lead author Roel Verhaak, Ph.D. assistant professor of Bioinformatics and Computational Biology at The University of Texas MD Anderson Cancer Center.
A small population of cells, known
as glioblastoma stem cells, often survives the onslaught and continues to divide, producing new tumor cells to replace the ones killed by the cancer drugs.
This informatics challenge is often a critical bottleneck when dealing with deadly cancers
such as glioblastoma, with a median survival of less than 15 months following diagnosis.
Berkeley Lab researchers have developed a new family of nanocarriers, called «3HM,» that meets all the size and stability requirements for effectively delivering therapeutic drugs to the brain for the treatment of a deadly form of cancer
known as glioblastoma multiforme.
Dr Steve Pollard and his team are developing potential new treatments for the most common type of brain tumour in adults, known
as glioblastoma multiforme.
«Our study identified miR - 182
as a glioblastoma tumor suppressor that reduces the expression of several oncogenes that promote cancer development,» said senior author of the study Alexander Stegh, an assistant professor in the Ken and Ruth Davee department of neurology and of medicine at Northwestern University Feinberg School of Medicine.
This discovery has relevant implications for understanding neuroinflammation and even brain malignancies such
as glioblastoma.
Whereas some types of tumor respond well to treatment, others such
as glioblastomas — the most common and aggressive brain tumors — are known to recur and progress within short times from the diagnosis.
But a new technique tested in mice and rats might provide a tool to combat the lethal tumors, known
as glioblastomas.
These factors are important in the treatment of invasive tumors, such
as glioblastoma.
A statement from his office said it was «revealed that a primary brain tumor known
as glioblastoma was associated with the blood clot.»
At McCain's request, the Mayo Clinic, which is treating him, released a statement explaining that «tissue pathology revealed that a primary brain tumor known
as a glioblastoma was associated with the blood clot» that was removed.
Currently, extensive research is conducted to better understand the role of certain cohesin mutations in cancers such
as glioblastoma, or Ewing's sarcoma.