For the detection of specific antigens, the following primary antibodies were used: mouse monoclonal anti-Tuj1 (Covance, Princeton, NJ, USA) as a neuronal marker, rabbit anti-L1 (kindly provided from Dr. Asou)[52] and rat monoclonal anti-L1 (Millipore, Billerica, MA, USA)
as granule cell markers, rabbit anti-calbindin D28K (Millipore) as a Purkinje cell marker, and rabbit anti-glial fibrillary acidic protein (GFAP, DAKO, Denmark) as an astrocyte marker.
Not exact matches
NK
cells are cytotoxic; small
granules in their cytoplasm contain special proteins such
as perforin and proteases known
as granzymes.
Here we identify protein kinase N1 (PKN1)
as a novel key player in fine - tuning the balance between axonal outgrowth and presynaptic differentiation in the parallel fiber — forming (PF - forming) cerebellar
granule cells (Cgcs).
In this context, we have studied the role of ERK7 in Drosophila S2
cells in response to serum starvation, and have shown that amino - acid starvation leads to the formation of a of novel membrane-less stress assembly, the Sec bodies,
as well
as stress
granules.
Lipofuscin
granules, melanosomes
as well
as melanolipofuscin
granules disintegrated within the RPE
cells and / or were released to macrophages.
A beta 42 first selectively accumulates in the perikaryon of pyramidal
cells as discrete,
granules that appear to be cathepsin D - positive, suggesting that they may represent lysosomes or lysosome - derived structures.
Enormous
granules, otherwise known
as convection
cells, imaged on the surface of the red giant star π1 Gruis (Credit: ESO)
This RNA binding protein, upregulated upon B
cell activation, post-transcriptionally regulates components of the DNA damage repair machinery, such
as p53, silencing the mRNA and keeping the transcripts captive in RNA stress
granules.
Mast
cells contain
granules filled with substances which can be released into the bloodstream and potentially cause systemic problems, including stomach ulceration and bleeding, swelling and redness at and around the tumor site, and potentially life - threatening complications, such
as a dangerous drop in blood pressure and a systemic inflammatory response leading to shock.
Mast
cells are quite distinctive under the microscope
as they have purple
granules inside the
cell.
Mast
cell granules contain histamine, which can be irritating to your dog's intestinal tract, and your veterinarian may recommend long - term treatment with antihistamines such
as Benadryl to counteract this problem.