Without these two technologies that you'll hear about in a moment, there would be no such thing
as human embryonic stem cell research, and President Bush could have enjoyed his summer vacation in Crawford without having to agonize over the baptism of the infamous 64 stem cell lines.
He also discussed his current viewpoint on whether induced pluripotent stem cells (iPS)-- which are derived from adult cells — will have the same potential therapeutic utility
as human embryonic stem cells.
Beginning in the 1990's, and throughout the first years of the 21st century, perhaps no other political or social cause célèbre attracted as many celebrities
as human embryonic stem cell research (hESCR).
Scientists have long known that
as human embryonic stem (ES) cells age, they develop genetic mutations that could limit their medical usefulness.
Not exact matches
Benedict argued that non-conjugal reproduction such
as in vitro fertilization had created «new problems» ¯ the freezing of
human embryos, for instance, and the selective abortion of medically implanted embryos, together with pre-implantation diagnosis,
embryonic stem - cell research, and attempts at
human cloning.
research; since most of the reports have concentrated on justifying the creation of cloned
human embryos for research into and treatment of neurodegenerative diseases such
as Parkinson's, «
stem - cells» has become synonymous with «
embryonic stem - cells» in the public imagination.
Human cloning has been proposed as a means of generating human embryos that can be destroyed to obtain embryonic stem c
Human cloning has been proposed
as a means of generating
human embryos that can be destroyed to obtain embryonic stem c
human embryos that can be destroyed to obtain
embryonic stem cells.
Former Senator Rick Santorum (R — PA) is a strong backer of adult
stem - cell research, and opposed to
embryonic stem - cell research because he views destruction of embryos
as destruction of
human life.
On Thursday, the United Nations» member states will consider two resolutions: One resolution would ban all
human cloning methods, including efforts to use cloned
embryonic stem cells to try and generate healthy tissues, or to treat degenerative diseases such
as Parkinson's.
The ability of SIF - seq to use reporter assays in mouse
embryonic stem cells to identify
human embryonic stem cell enhancers that are not present in the mouse genome opens the door to intriguing research possibilities
as Dickel explains.
Human embryonic stem cells are at last being tested in common, potentially fatal diseases such
as heart failure and diabetes
Decades after they were discovered,
human embryonic stem cells are being trialled
as a treatment for two major diseases: heart failure and type 1 diabetes
Induced pluripotent
stem cells (known
as iPSCs) are similar to
human embryonic stem cells in that both cell types have the unique ability to self - renew and have the flexibility to become any cell in the
human body.
Using a mathematical model known
as the Ising model, invented to describe phase transitions in statistical physics, such
as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different
human cell types, including normal and cancerous colon, lung and liver cells,
as well
as brain, skin, blood and
embryonic stem cells.
The newly discovered
human cells, named «cord - blood - derived
embryonic - like
stem cells» or CBEs, are not quite
as primitive
as embryonic stem cells, which can give rise to any tissue type of the body.
A person with spinal injuries today went down in history
as the first to receive a treatment derived from
human embryonic stem cells (hESCs).
Scientists, with practice, have now been able to make nuclear transfer nearly routine to produce cattle, cats, mice, sheep, goats, pigs, and —
as a Korean team announced in May — even
human embryonic stem (ES) cells.
In this way they act like
embryonic stem cells and share their revolutionary therapeutic potential — and
as such, they could eliminate the need for using and then destroying
human embryos.
In an advance touted
as a way around current political logjams, scientists have said they can derive
human embryonic stem (ES) cell lines without destroying an embryo.
TOKYO — Research involving
human embryonic stem (ES) cells will become easier in Japan
as a result of new ethical review requirements that take effect today.
Lamberth granted a preliminary injunction on this research after hearing a petition from a group of advocates who argued that, contrary to the U.S. government's view, research on
embryonic stem cells does in fact destroy embryos — action that is prohibited by legislation known
as the «Dickey - Wicker Amendment» to the bill that funds the Department of Health and
Human Services.
• News of
Embryonic Stem Cells • A University of Wisconsin team used human embryonic cells to form cells that manufacture platelets as well as red and white blo
Embryonic Stem Cells • A University of Wisconsin team used
human embryonic cells to form cells that manufacture platelets as well as red and white blo
embryonic cells to form cells that manufacture platelets
as well
as red and white blood cells.
The reprogrammed skin cells that have led to this enthusiasm seem to have the same properties
as the
embryonic stem cells (ESCs) found in
human embryos just a few days old.
They view this
as a test run for creating
human embryonic stem cells in the same way (and according to the team, South Korean biologist Hwang Woo Suk seems to have accidentally accomplished this feat while executing his famously fraudulent
human cloning experiment).
But if homologous recombination could be worked out in
human (
embryonic)
stem cells, then cardiomyocytes with mutations in ion channels could be derived,
as well
as a large number of other very useful disease models of other tissues.
I don't think we need the same level of regulation
as for
human embryonic stem cells, for example, because we are not using any embryos.
As expected, the plaintiffs in a law suit claiming that federally funded research on
human embryonic stem cells (hESC) is illegal have appealed a ruling that dealt them a defeat earlier this summer.
This gene is also known to help
human embryonic stem cells stay flexible enough to become any type of body cell, a property known
as pluripotency.
Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory - generated
stem cells comes to mimicking
embryonic cells seen in the very earliest stages of
human development, known
as naïve
stem cells.
Lamberth, who ordered a temporary ban on federal funding for
human embryonic stem cells research last August that an appeals court later overturned, is expected to issue a final ruling on the matter
as soon
as this summer.
Embryonic stem (ES) cells, harvested from three - and - a-half-day-old mouse embryos or five - and - a-half-day-old
human embryos, are referred to
as pluripotent because they can become any of the thousands of cell types in the body.
Replacement tissue that avoids rejection by a patient's immune system is a step closer to the clinic,
as researchers have created
human embryonic stem cells carrying the DNA of specific adults.
A trial in 18 people with damaged retinal cells is being hailed
as the most promising yet for a treatment based on
human embryonic stem cells (hESCs).
Research involving
human embryonic stem cells will become easier in Japan
as a result of new ethical review requirements that took effect 21 August.
Because embryos are not destroyed to create them, they have been hailed
as a way out of the ethical dilemma posed by
human embryonic stem cells.
Skin cells reprogrammed to act like
embryonic stem cells — a breakthrough first reported in
human cells 2 weeks ago — are already showing promise
as a therapeutic agent.
When the researchers added a specific bone morphogenetic protein called BMP4,
as well
as another signaling molecule called retinoic acid, to
human embryonic stem cells, they got a mixture of two types of sensory interneurons.
«When we look back in 25 years, putting the first
embryonic stem cells into
humans will prove
as momentous
as man's first step on the moon.»
Other potential uses of
embryonic stem cells include investigation of early
human development, study of genetic disease and
as in vitro systems for toxicology testing.
Human embryonic stem cells derived from affected embryos during a pre-implantation diagnostic (PGD),
as well
as the conversion of somatic cells, such
as skin fibroblasts, into induced pluripotent
stem cells by genetic manipulation, offer the unique opportunity to have access to a large spectrum of disease - specific cell models.
Benedict argued that non-conjugal reproduction such
as in vitro fertilization had created «new problems» ¯ the freezing of
human embryos, for instance, and the selective abortion of medically implanted embryos, together with pre-implantation diagnosis,
embryonic stem - cell research, and attempts at
human cloning.
Lamba and colleagues recently demonstrated that
human embryonic stem cells could be directed to differentiate into photoreceptors and respond to a light stimulus
as measured by ERG in crx − / − mice (a model for Leber's congenital amaurosis)[5].
When transplanted to the subretinal space of mice lacking functional photoreceptors,
human embryonic stem cells directed toward a retinal lineage integrate into the outer nuclear layer, express photoreceptor markers, and restore a light response
as determined by the electroretinogram (ERG)[5].
Human Embryonic Stem (hES) cells derived from Preimplantation Genetic Diagnosed (PGD)- embryos offer a new alternative source of cellular model
as they can be largely expanded, differentiated in several cell types and harbors «naturally» the causative mutation of the pathology.
For the first time, through the use of
human embryonic stem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
stem cells (hES) sourced from pre-implantation diagnosis, researchers from Inserm's Institute for
Stem Cell Therapy and Exploration of Monogenic Diseases (I - Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
Stem Cell Therapy and Exploration of Monogenic Diseases (I -
Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known as type 1 myotonic dystro
Stem) have successfully identified the previously unknown mechanisms involved in Steinert» disease, also known
as type 1 myotonic dystrophy.
To do so, they started with a
human embryonic stem cell line, which they chemically nudged to become cells that form what's known
as the primitive streak on the hollow ball of cells of the early embryo.
NeuroStemcell is focused on the identification and systematic comparison of progenitor cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from
human embryonic stem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals mod
stem (ES) cells, from Neural
Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals mod
Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent
Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals mod
Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown
as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals models.
Figure 1: The blastocyst is a hollow sphere made of approximately 150 cells and contains three distinct areas: the trophoblast, which is the surrounding outer layer that contains the trophoblast
stem cells and later becomes the placenta, the blastocoel, which is a fluid - filled cavity within the blastocyst, and the inner cell mass, also known
as the embryoblast, which can become the embryo proper, or fetus, and is where
human embryonic stem cells are isolated from.
Not so long ago,
human embryonic stem cell (hESC) research and SCNT were being hailed
as the future of regenerative medicine, capable of generating cures and therapies for any number of diseases and conditions.
Enriched population of PNS neurons derived from
human embryonic stem cells
as a platform for studying peripheral neuropathies.