Raising a child with a hypoxia - related birth injury (such
as hypoxic - ischemic encephalopathy) can cost a small fortune.
In Amed, our tech instructor is qualified
as a hypoxic trimix diver and can accompany you to depths of 100m.
Dysfunctional microbiomes are associated with issues including human chronic diseases such as obesity, diabetes, and asthma; local ecological disruptions such
as the hypoxic zone in the Gulf of Mexico; and reductions in agricultural productivity.
Not exact matches
This is becoming less common since it was shown that cerebral palsy isn't necessarily an intra-partum event, but generally a live baby with brief breathing issues who might need a short NICU stay is seen
as a better outcome than either death or
hypoxic damage.
Inga is wet and cooling and
as she becomes
hypoxic, not only can't she curl up to conserve heat, she basically becomes unconscious and is
as exposed
as she can possibly be.
Lothar Stramma, a physical oceanographer at the Christian Albrechts University of Kiel in Germany and his associates describe the
hypoxic problem
as global in a paper accepted for publication in Deep - Sea Research, stating that tropical low - oxygen zones have expanded horizontally and vertically around the world, and that subsurface oxygen has decreased adjacent to most continental shelves.
They have engineered macrophages to deliver a therapeutic virus to
hypoxic tumor regions, which respond poorly to conventional treatments such
as chemotherapy and radiation because of an insufficient blood supply.
Their consumption of oxygen could create
hypoxic zones and have «a serious influence on biodiversity at those times
as well,»
Cadherin - 22 is located on cell surfaces, allowing
hypoxic cancer cells to stick together and migrate collectively
as a group, said Uniacke.
NOAA - supported scientists found a large Gulf of Mexico oxygen - free or
hypoxic «dead» zone, but not
as large
as had been predicted.
Two surveys conducted in June and early July, one of which was led by a NOAA - supported Texas A&M University team, suggested a large
hypoxic zone was forming in the Gulf, though the LUMCON July measurement will be the official one
as required of NOAA by the Task Force.
As the duration and extent of
hypoxic areas is predicted to increase in coastal regions, it is likely that some species will be exposed chronically throughout their life cycle.
The subjects also experienced
hypoxic effects,
as cessations in breathing cause blood oxygen saturation levels to drop, possibly triggering optic nerve damage that can lead to glaucoma.
Farmland runoff containing fertilizers and livestock waste is the main source of the nitrogen and phosphorus nutrients that cause the annual Chesapeake Bay
hypoxic region, which is also known
as a dead zone.
Hypoxic (very low oxygen) and anoxic (no oxygen) zones are caused by excessive nutrient pollution, often from human activities such
as agriculture, which results in insufficient oxygen to support most marine life in near - bottom waters.
Rats born of
hypoxic pregnancy with no vitamin C treatment showed increased thickening of the walls of the aorta — up to 170 % above normal — and molecular markers of disease, such
as an increase in the heart's heat shock proteins, a signal of cardiac oxidative stress.
«Oregon's Coos Bay historically has avoided serious
hypoxic conditions: Narrow offshore shelf, a dredged ship channel and fresh river water combine to keep the bay flushed, but that could change
as the climate warms.»
They play a pivotal role in regulating synaptic transmission, modulating excitotoxicity responsible for much of the neuronal damage caused by
hypoxic insult in the brain [37], and are expressed in retinal photoreceptors, horizontal cells, and bipolar cells
as well
as the amacrine and ganglion cells of the inner retina [38 — 41].
The genes identified
as differentially expressed when comparing
hypoxic and control retinal samples and when comparing recovery and control retinal samples at a FDR of approximately 5 % were examined for their biologic association to GO categories.
Microarray analysis was performed at different time points to determine yeast genome - wide response when exposed to salt, acid,
hypoxic conditions, and hydrogen peroxide,
as well
as ethanol, isopentenol, and other biofuels candidates.
Perfusion of microvessels in Tie2PEKO mice was further confirmed by similar extent of
hypoxic areas
as compared to tumours growth in wild - type mice (Supplementary Fig. 12b).
Support to date for the existence of an
hypoxic niche in marrow blood stem cells came from indirect evidence such
as expression of the hypoxia protein Hif - 1 and related genes and staining with surrogate markers of hypoxia.
Our findings suggest that this is also true in breast cancer
as EGFR inhibition blocked the
hypoxic CSC effect in ER - α — positive tumors.
In summary, our novel data suggest that ER - α — positive and negative breast cancer subtypes respond differently to
hypoxic exposure and
as a consequence, anti-HIF-1α or antiangiogenic therapies will not be suitable for both subtypes.
Current studies include the exploration of Arctic deep - sea life under the ice, and the long - term observation of the effects of global warming on polar ecosystems
as well
as on
hypoxic aquatic ecosystems.
There may be a certain level of complexity in elucidating the mechanisms involved in this negative response
as we have shown that the response can be easily altered with expression of either ER - α or N1 - ICD, and this suggests that the intrinsic
hypoxic response of these cells can be overcome quite simply.
As distinct
hypoxic responses were observed between ER - α — positive and negative breast cancers, we hypothesized that the response seen in ER - α — positive cancers was downstream of ER - α.
As the mechanistic studies suggest that ER - α and Notch are central in mediating the unfavourable
hypoxic CSC response in ER - α — positive breast cancer, they may offer an attractive combination treatment approach, which would consist of ER - α or Notch inhibitors combined with antiangiogenic drugs.
-15 minutes of
hypoxic / hyperoxic training on my bicycle, which is set up next to a LiveO2 unit that allows me to switch between hypoxia (low oxygen) and hyperoxia (high oxygen)
as I work through a series of short, explosive sprints.
As the algae died and settled, they created a
hypoxic area.
Such changes, along with diminished water quality, probably contribute to the growing number and size of
hypoxic or anoxic areas, such
as those in the Gulf of Mexico and along the West Coast, which have profound biotic impacts.
Threats to marine biodiversity in the U.S. are the same
as those for most of the world: overexploitation of living resources; reduced water quality; coastal development; shipping; invasive species; rising temperature and concentrations of carbon dioxide in the surface ocean, and other changes that may be consequences of global change, including shifting currents; increased number and size of
hypoxic or anoxic areas; and increased number and duration of harmful algal blooms.
The resulting injury led to the baby undergoing a cardiac arrest, which developed into a devastating
hypoxic brain injury
as a consequence of dangerously low oxygen levels.
This condition is so dangerous that it often causes the death of either the mother or the baby, or severe developmental issues such
as cerebral palsy or
hypoxic ischemic encephalopathy.
Hypoxic Ischemic Encephalopathy (HIE), brain damage that can result from the cutting off of oxygen to the brain
as a whole
Hypoxic birth injuries (such
as HIE or white matter injury) may also lead to the development of cerebral palsy.
Personal injury cases related to
hypoxic brain injuries are often associated with birth injuries or other forms of medical negligence,
as well
as near - drowning incidents.