Not exact matches
Postpartum haemorrhage (PPH) has been
identified by the UK Care Quality Commission
as one of three «potential
markers relating to the risk of maternal mortality» [10].
Here we have again the phenomenon that City Council Watch has long
identified as the signal
marker of a decayed political culture: the election of Chiefs of Staff to succeed their bosses.
To
identify position - taking, listen for phrases that are
markers of time - «today», «tonight», «
as we speak», «five years ago», «I remember when» - or
markers of place like «Britain» or «our country».
Individuals were classified
as high risk for Alzheimer's if a DNA test
identified the presence of a genetic
marker — having one or both of the apolipoprotein E-epsilon 4 allele (APOE - e4 allele) on chromosome 19 — which increases the risk of developing the disease.
«Recent scientific advances have enabled us to
identify a trove of neurotransmitters and detect relevant neural brain pathways
as well
as genetic
markers that help explain the biology of the placebo effect,» said Kaptchuk.
Through a new study of the coccobacillus Francisella, Los Alamos National Laboratory researchers are working to use DNA
markers to discern related but relatively harmless species
as they are
identified and to provide a means to distinguish them from the harmful F. tularensis.
The first was to search publicly available databases such
as PubMed and GenBank to
identify markers or DNA sequences in the published literature.
«We hope that our work will provide the basis for a larger study of patient samples that may ultimately
identify biomarkers that can be used
as surrogate
markers to determine the benefit of therapeutic interventions in diagnosed but asymptomatic HD patients to prevent or delay disease onset.»
Mental illness, he adds, has too long been regarded
as simply mental: «
Identifying the biological
markers and risk for mental illness in early childhood may ultimately have a huge impact on human and economic health.
«These lung breakdown products have never been
identified in TB before, and have the potential to be used
as new
markers to
identify patients with TB and monitor the effect of new treatments on lung damage.
«This opens a new door in
identifying biological
markers for dementia since we might consider using the brain's processing of speech sounds
as a new way to detect the disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University of Toronto's psychology department.
The $ 138 million HapMap denotes haplotypes, stretches of DNA that are inherited together
as unbroken blocks and can be
identified by just a handful of DNA
markers known
as SNPS (single nucleotide polymorphisms).
In case a
marker was moved, so - called «witness trees» near the stake were
identified as reference points.
This is the first study to
identify histone crotonylation
as a driver for HIV transcription and de-crotonylation of histone
as an epigenetic
marker for HIV silencing.»
Scientists at CNRS, Aix - Marseille Université and AP - HM have
identified a cerebral
marker specific to autism that can be detected by MRI and is present
as from the age of two years.
They found that women were five times
as likely to develop cancer if they had a higher percentage of Ki67, a molecular
marker that
identifies proliferating cells, in the cells that line the mammary ducts and milk - producing lobules.
Due to the growing prevalence of ASD (1 in 68 children in the U.S.) and the lack of objective
markers,
identifying remote eye gaze tracking
as an objective measure of autism could aide early identification leading to more rapid treatment.
If expressed genes are
identified in a fungus but not in another, they serve
as markers that will allow to apply the appropriate treatment in these crops, says Dr. Elsa Gongora Castillo, plant biotechnologist who works at North Carolina State University.
Next steps for the team include
identifying microbiota metabolites whose levels are either significantly elevated or depleted during diseases such
as IBD or cancer, to find disease - specific
markers and explore possible roles for these metabolites in disease progression.
Our team proposes using the strains containing all the
identified evolutionary
markers as vaccine candidates for upcoming influenza seasons,» Kainov continues.
Van der Greef suspects that many diseases have metabolic signatures that technology can detect even before a
marker such
as cholesterol would be elevated — the challenge is to
identify the patterns.
This observation is further supported by the fact that studying alterations in the expression of genes also made it possible to
identify persons whose levels of interleukin 6, an inflammation
marker, were reduced
as their serum vitamin D levels increased.
And finally, we have to
identify markers that can predict HIV response to the anti-PD-1 therapy so that treatment can be personalised, especially
as we observed one responder and one non-responder.»
A newly published International Osteoporosis Foundation (IOF) and European Calcified Tissue Society (ECTS) Working Group position paper [1] proposes measuring specific bone turnover
markers (BTMs) in patients who have initiated use of oral bisphosphonates for postmenopausal osteoporosis
as a clinically feasible and practical way to
identify low adherence.
By studying video footage of children interacting with a psychiatrist, computer - vision algorithms learn to
identify behavioural
markers as designated on the Autism Observation Scale for Infants.
Most simply, once these genes, or bits of DNA tied to the genes (known
as markers), have been
identified, molecular breeders can quickly target offspring inheriting the genes for further development, cutting breeding time and improving the crop's «genetic gain,» the generational improvements made to a crop, like increased height, by human selection.
The researchers believe that they have
identified a group of RNA molecules — known
as long noncoding RNAs (lncRNAs)-- that hold the potential for serving
as better prognostic
markers for prostate cancer.
Paul Marks discusses the possibility of using otoacoustic emissions (OAEs)
as a biometric
marker that could be used to
identify...
«Our findings suggest that we can quickly and reliably
identify whether an infant has a bacterial infection or not by analyzing RNA biosignatures, which are genomic
markers of the child's immune response,» said Elizabeth Powell, MD, MPH, study co-author and emergency department physician at Ann & Robert H. Lurie Children's Hospital of Chicago,
as well
as Professor of Pediatrics at Northwestern University Feinberg School of Medicine.
This is why our system is innovative and powerful,
as we don't have to spend the time to
identify and develop a new genetic or protein
marker for every kind of cancer.»
A protein known
as suPAR has been
identified in recent years
as both a reliable
marker for chronic kidney disease and a pathogen of the often deadly condition.
Lin and Artandi wondered whether they could use telomerase expression
as a
marker to
identify the subset of cells responsible for regenerating the liver during normal turnover.
To develop a model for generating the human colon, scientists first
identified SATB2 (special AT - rich sequence - binding protein 2)
as a definitive molecular
marker for hindgut in frogs, mice and in humans.
Hence, understanding the interrelationship between genetic
markers and use of aspirin and NSAIDs, also known
as gene × environment interactions, can help to
identify population subgroups defined by genetic background that may preferentially benefit from chemopreventive use of these agents and offer novel insights into underlying mechanisms of carcinogenesis.
The oncogene was coupled with a fluorescent
marker so that cells in which the oncogene was active could be easily
identified, and
as these cells proliferate, their «daughter» cells could also be tracked.
Epigenomics is presently being used to
identify inherited pre-disposition to obesity, diabetes, cardiovascular disease, addiction and psychiatric disorders,
as well
as markers for aging and cancer progression.
Metagenomics initially
identified Israeli acute paralysis virus (IAPV)
as a potential
marker or cause of CCD [4], yet a subsequent study demonstrated that IAPV was in the USA long before the recent CCD outbreaks [5].
HLA (human leukocyte antigen)-
markers on the surface of a body's cell that
identify the cell
as one's own (
as opposed to a foreign cell) and prevent the immune system from attacking itself.
Ultimately, this will provide for current and future studies such
as those that evaluate the correlation of biological
markers with clinical variables and cancer outcomes,
as well
as those that
identify interactions among biological
markers.
In a previous study, we used kakusei
as a neural activation
marker to
identify the brain regions in the European honeybee that are active during foraging behavior [13], [14].
A lot of effort in tumor stem cell research has always been directed to finding a so - called
marker, a molecule whose presence on a cell reliably
identifies it
as a cancer stem cell.
Chemoproteomic Profiling
Identifies Changes in DNA - PK
as Markers of Early Dengue Virus Infection % U http://pubs.acs.org/doi/abs/10.1021/cb300420z.
In collaboration with data - sharing networks, namely MalariaGEN and STOP - HCV, they are using genetics
as a tool to investigate the underlying biology of infectious diseases and to
identify genetic
markers that correlate with clinical outcomes.
Macrophages were
identified by their typical morphology,
as well
as by their reactivity to the cell surface
marker F4 / 80 (Fig. 2A) ⇓.
We focus on developing computational methods and tools for (a) analyzing large - scale gene expression data related to human cancer in search for gene
markers and disease sub-categories, (b)
identifying regulatory elements such
as miRNA precursors and their targets in whole genomes of plants and mammals, (c) building theoretical models of gene regulatory networks.
Using single water molecules
as atomic
markers, the team successfully
identified the atomic species of this surface; result that was additionally confirmed by the comparison of simultaneous AFM and STM measurements with the outcomes of first - principles calculations.
Since very few studies have demonstrated the formation of macro-metastasis from low numbers of sorted CSCs and currently proposed CSC
markers might not be sufficient to
identify all stem cell populations [13], we believe that our study presents a promising approach to isolate stem - like and metastatic breast CSCs
as opposed to the cell - sorting strategy based on putative stem cell surface
markers.
To date, a screen of the collection of FDA - approved drugs in the Prestwick Library has
identified a handful of potential candidates which have demonstrated effectiveness at lowering secretion of IL - 6, a component of SASP whose concentration tends to rise systemically with aging and here used
as a preliminary
marker of SASP
as a phenotype.
Floryne Buishand, 30, from the Netherlands, is a postdoctoral researcher at the National Cancer Institute / NIH, Bethesda, USA, studies genomic changes associated with endocrine cancers with the ultimate goal of
identifying novel diagnostic and prognostic
markers,
as well
as novel therapeutic targets.
My short term goals for my postdoc are to
identify novel diagnostic and prognostic
markers,
as well
as novel therapeutic targets, leading to several high impact first authored publications.