Prompt diagnosis and treatment of secondary infections - more prolonged therapy may be needed
as the immunosuppression may mean response to therapy is slower
«However,
as immunosuppression drugs required for transplantation can have significant adverse side effects, the treatment only makes sense for people who have frequent severe hypoglycemia despite optimal diabetes management, or for those already on immunosuppressant drugs for a kidney transplant, a group being studied in another Phase 3 trial.»
Not exact matches
«Our data suggest that
immunosuppression may not be the best strategy to help virotherapy do its job,» said Dr. Cripe, who was recently appointed
as an associate editor of Molecular Therapy — Oncolytics.
Consequently, they hope that their results will «motivate the incorporation of assays measuring ex-vivo T - cell function into ongoing and planned clinical trials of HDAC inhibitors, and that
immunosuppression will be considered
as a potential factor limiting the effectiveness of any observed outcomes.»
In addition, no
immunosuppression is required, so patients would avoid related side effects such
as an increased risk of infection.
This is a desirable feature for a helper drug
as it would reduce the risk of treatment failure due to factors other than antibiotic resistance (e.g. biofilms,
immunosuppression, etc.), allow dose reduction for toxic antibiotics such
as colistin, and possibly even prevent selection of resistant mutants» says Guardabassi.
Furthermore, severe infections from human adenoviruses are more commonly associated with older age,
immunosuppression, and chronic underlying conditions such
as kidney failure [4], [41].
No patient lost his / her hand if they took their
immunosuppression drugs on time and
as advised.
The GRIP1: IRF3 interaction
as a target for glucocorticoid receptor - mediated
immunosuppression.
Now, improved
immunosuppression allows increased use of biologically dissimilar but emotionally related kidney donors, such
as a spouse.
As such, PEC - Direct will require immunosuppression therapy, and is being developed for type 1 diabetes patients that are at a higher risk of death due to complications, such as severe hypoglycemic episodes, extreme glycemic lability and hypoglycemia unawarenes
As such, PEC - Direct will require
immunosuppression therapy, and is being developed for type 1 diabetes patients that are at a higher risk of death due to complications, such
as severe hypoglycemic episodes, extreme glycemic lability and hypoglycemia unawarenes
as severe hypoglycemic episodes, extreme glycemic lability and hypoglycemia unawareness.
The results were unexpected,
as our animals were not treated with any
immunosuppression other than the sublethal irradiation pre-HPC infusion, either pre - or post-transplantation.
Transplanted patients are a major challenge both in terms of prevention
as well
as diagnosis and treatment of infectiological complications, due to the inevitable
immunosuppression.
In bees,
as in humans, diet would play a key role in
immunosuppression.
With much of our pets» energy being used to thermoregulate,
as well
as stresses induced by the colder weather, many of our dogs suffer from
immunosuppression, becoming more susceptible to illnesses.
They possibly have a direct effect on pain mediators such
as substance P. Although corticosteroids may be effective in limiting the signs and progression, most dogs require continuous therapy and subsequently develop the concomitant side effects of
immunosuppression, weight gain and skin changes.
Failure to control internal parasites can result in a decrease in feed intake and general
immunosuppression leading to increased sickness during the feeding period.1, 2 The injectable avermectin products, such
as doramectin, provide superior efficacy at controlling internal parasites, while pour - on products provide the best control for external parasites.
In a cat persistently (permanently) infected with the virus, there is significant risk of developing many severe illnesses such
as anaemia,
immunosuppression and cancer.