Sentences with phrase «as in human patients»

In 2012, he showed that interfering with phosphorylation of the membrane protein aquaporin - 0 results in cataracts that are visually the same as those in a human patient.

Not exact matches

There in the closed room, where one probed and treated the isolated psyche according to the inclination of the self - encapsulated patient, the patient was referred to ever - deeper levels of his inwardness as to his proper world; here outside, in the immediacy of human standing over against each other, the encapsulation must and can be broken through, and a transformed, healed relationship must and can be opened to the sick person in his relations to otherness — to the world of the other which he can not remove into his soul.

As we read this history, the furor over stem cells was fueled by numerous factors: the near - universal human desire for magic; patients» desperation in the face of illness and their hope for cures; the belief that biology can now do anything; the reluctance of scientists to accept any limits (particularly moral limits) on their research; the impact of big money from biotech stocks, patents, and federal funding; the willingness of America's elite class to use every means possible to discredit religion in general; and the need to protect the unlimited abortion license by accepting no protections of unborn human life.

He has helped the patient to «adjust himself to life,» but in either case he has helped a human being to fit into a pattern of human life without giving him any clue as to whether it is the right pattern.

In spite of his fascination with theory, Jung observed: «It is a remarkable thing about psychotherapy: you... can cure only from one central point; that consists in understanding the patient as a psychological whole and approaching him as a human being, leaving aside all theory and listening attentively to whatever he has to say.&raquIn spite of his fascination with theory, Jung observed: «It is a remarkable thing about psychotherapy: you... can cure only from one central point; that consists in understanding the patient as a psychological whole and approaching him as a human being, leaving aside all theory and listening attentively to whatever he has to say.&raquin understanding the patient as a psychological whole and approaching him as a human being, leaving aside all theory and listening attentively to whatever he has to say.»

Just as the patient's trust in, and devotion to, the hypnotist would lack for the latter the value of a freely given trust and devotion, so our human worship and obedience to God would lack for Him the value of a freely offered worship and obedience.

This is an in - depth and far - reaching conversation that includes dialogue about euthanasia, blood transfusions, medical experimentation without consent, research fraud, vaccines as biological weapons, autism, the rape of autistic children, the rape of medical patients — especially during hospital birth, birth trauma, trauma - based mind - control, circumcision, satanism / luciferianism, psychopathy, Agenda 21, and the deliberate attempt to kill and / or render infertile and / or genetically mutate the human race.

She trained and volunteered as an intrapartum doula, opening her eyes to the imperatives of informed consent and health as a human right, and subsequently pursued a nursing career in in - patient obstetrics.

Yesterday he stepped out from behind the human shield of Mr Clegg to defend misguided health reforms that many professionals regard as ushering in worse patient care and back - door privatisation.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

A dozen human studies of MDMA, LSD, a powerful African drug called ibogaine and psilocybin, from so - called «magic mushrooms,» are now under way, testing the once - stigmatized drugs as treatments for not only PTSD, but also cluster headaches and addiction, as well as anxiety and depression in cancer patients.

Ubogu says the findings are very exciting, as they provide knowledge of leukocyte trafficking in human nerves, but more work needs to be done in affected patients to develop an effective drug.

«Data from this study serves as rationale to now include dogs with spontaneous cancers in the advancement and optimization of PMed for human patients,» according to the study, Prospective molecular profiling of canine cancers provides a clinically relevant comparative model for evaluating personalized medicine (PMed) trials.

Besides its potential application in human patients, the newly developed skin tissue also could be used as an alternative to testing cosmetics on animals, the researchers said.

ASMI researchers are involved in different fields such as biomechanics (motion analysis, which includes cadaver research, namely, the use of human limbs to analyze anatomy, motion, and the strength of muscles, tendons, ligaments, and bones) and clinical research (tracking patients to see how successful they are returning to sport after treatment with surgery or physical therapy).

It typically takes many years to initiate such trials because of the stringent safety testing that must be done before testing in humans begins, but Reynolds said it may be possible to move faster as the therapy only involves modifying a patient's dietary intake and supplementing with a medium - chain triglyceride oil, both of which have no known side effects.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

«The human genes and pathways that Tat manipulates correlate well with symptoms observed in these patients, such as immune system hyperactivation, then weakening, and accelerated aging,» Dr. D'Orso said, describing the situation in which HIV infection leads to AIDS.

When a physican needs help diagnosing or treating a patient they open the Human Dx smartphone app or visit the project's Web page and type in their clinical question as well as their working diagnosis.

The common pathway found in mouse models was also found in human tumors, suggesting that resistance could indeed be blocked in patients with the same drug as in mice.

The first - in - human PET / CT imaging of 75 patients with 18F - MPG was performed to show that this tracer can be used as a companion diagnostic to identify NSCLC patients with EGFR activating mutant tumors (primary tumor or metastatic) with 84.3 % accuracy.

This «smart» patch, covered in nearly 100 needles the size of human eyelashes, could one day serve as a blood glucose monitor and at the same time replace insulin injections for diabetics — a painful ritual that some patients have to go through several times a day.

If the findings hold true in humans, rapamycin could provide considerable benefits to spinal cord injury patients, up to 80 percent of whom experience clinically significant pain that is described as burning, stabbing, and electric shock - like.

In humans it could potentially treat Type 1 diabetes in early stage patients, during what is known as the «honeymoon period,» when the pancreatic beta cells have not been completely destroyed and continue to secrete insuliIn humans it could potentially treat Type 1 diabetes in early stage patients, during what is known as the «honeymoon period,» when the pancreatic beta cells have not been completely destroyed and continue to secrete insuliin early stage patients, during what is known as the «honeymoon period,» when the pancreatic beta cells have not been completely destroyed and continue to secrete insulin.

Just as the technique restored kidney, muscle, and insulin - producing function in the mouse models, he sees a future for rejuvenating neuronal populations, maybe even one day in human patients.

They also found elevated granzyme A levels in blood samples taken from non-human primates infected with chikungunya, as well as from human chikungunya patients.

«A significant amount of work remains in the development of teixobactin as a therapeutic antibiotic for human use — we are probably around six to ten years off a drug that doctors can prescribe to patients — but this is a real step in the right direction and now opens the door for improving our in vivo analogues.»

The Thorough QT clinical assessment also has its limitations, as those studies are done in humans and typically require large numbers of patients.

«By analyzing mice with the WNT10A mutation, as well as tissues from human patients with WNT10A mutations, we found that WNT10A regulates the proliferation, but not the maintenance, of stem cells in hair follicles,» said Sarah Millar, PhD, vice chair for Basic Research in the Department of Dermatology.

«The use of human cellular membranes as a decoy has the potential to block a large family of related microbial toxins and reduce the severity of invasive bacterial infections in vulnerable patients,» said Escajadillo.

The new study — published October 18, 2016 in the journal Molecular Psychiatry — combined genetic analysis of more than 9,000 human psychiatric patients with brain imaging, electrophysiology, and pharmacological experiments in mutant mice to suggest that mutations in the gene DIXDC1 may act as a general risk factor for psychiatric disease by interfering with the way the brain regulates connections between neurons.

Their findings, reported in Nature Communications, may shed light on human lung disease, in particular, the mechanism behind non-familial pulmonary hypertension in patients with conditions such as emphysema and pulmonary fibrosis.

There were, however, compatibility issues: The human immune system in most cases viewed the animal antibodies as alien and rejected them — or lacked the ammunition to destroy them, thereby making patients sicker.

Over the past two years, investigators from the Perelman School of Medicine at the University of Pennsylvania have reported results from a human trial in GBM using chimeric antigen receptor (CAR) T cell therapy, through which patients» own T cells were engineered to track down and kill cancer cells that express a tumor - specific protein known as EGFRvIII.

Historically, a surgeon's skills have been acquired in live patients, anaesthetized animals or human cadavers, but authors say surgical simulation is increasingly recognized as a vital educational tool.

«The primary mission of the USC Neurorestoration Center is to take advantage of resources from our clinical programs to create unique opportunities to translate scientific discoveries, such as those of the Andersen Lab at Caltech, to human patients, ultimately turning transformative discoveries into effective therapies,» says center director Charles Y. Liu, professor of neurological surgery, neurology, and biomedical engineering at USC, who led the surgical implant procedure and the USC / Rancho Los Amigos team in the collaboration.

If the new mechanism also operates in the human brain and can be potentiated, this could become of clinical importance not only for stroke patients, but also for replacing neurons which have died, thus restoring function in patients with other disorders such as Parkinson's disease and Huntington's disease,» says Olle Lindvall, Senior Professor of Neurology.

Previous studies have shown the drug to be effective at spurring new bone growth in mice and in humans with osteoporosis, and a U-M research team believes that it may spur new growth in brittle bone disease patients as well.

«Fasting blood sugar is easily measured and our findings suggest that it could serve as a useful measure in advising some patients on the type of diet that is most beneficial for their weight loss,» said senior author Sai Krupa Das, Ph.D., scientist in the Energy Metabolism Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston.

This week, he and his colleagues report a potentially significant step toward that goal: a recipe that can turn human stem cells into functional pancreatic β cells — the cells that are destroyed by the body's own immune system in type 1 diabetes patients such as Melton's son and daughter.

The researchers grafted breast or lung tumors in mice, allowed the tumors to grow to small size and removed these tumors surgically — essentially mimicking the situation in a human tumor patient in which the tumor is surgically removed as soon as possible after diagnosis.

If it works in humans, the technique could prolong the lives of some brain cancer patients, and it might be applicable to other types of cancer as well.

«Liver cancer is on the rise worldwide, and in human studies we've now seen that patients can progress from fatty liver disease to liver cancer without any middle steps such as cirrhosis,» says David Moore, a professor of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Baylor.

Buoyed by these results, Dana - Farber researchers are working to create a derivative of dBET1 that can be used as a drug in human patients — and to extend the conjugate strategy for the treatment of other cancers and other genetically - caused diseases.

«But a great deal of work lies ahead to see if this compound has the potential to serve as a less toxic treatment for fungal infections in human patients.

As a next step, Guha, Avadhani and colleagues plan to extend this study to in vivo mouse models and will also investigate these mechanisms in tumor samples from human breast cancer patients.

Liv Bode, a virologist at the Robert Koch Institut in Berlin whose team was the first to isolate the virus from patients, welcomes the findings as a «solid piece of work that fits the picture and lends further support to the existence of human [strains of] BDV.»

In yet another application of human medicine in veterinary care, the team has treated Northstar with gabapentin (sold under the brand name Neurontin), a medication used for neuropathic pain in humans, to treat the severe itching and nerve - related pain that is typical in burn patients as they recoveIn yet another application of human medicine in veterinary care, the team has treated Northstar with gabapentin (sold under the brand name Neurontin), a medication used for neuropathic pain in humans, to treat the severe itching and nerve - related pain that is typical in burn patients as they recovein veterinary care, the team has treated Northstar with gabapentin (sold under the brand name Neurontin), a medication used for neuropathic pain in humans, to treat the severe itching and nerve - related pain that is typical in burn patients as they recovein humans, to treat the severe itching and nerve - related pain that is typical in burn patients as they recovein burn patients as they recover.

North says his group has already generated a human chimeric form of MAG - 1 that is equally effective as mouse MAG - 1, and they are now generating a humanized form for use in patients.

But while most PDX mice are used as general models of human cancer in the laboratory, others seek to use them as Fiebig originally hoped — as avatars to guide customized patient care.