These are known
as joint mice.
Not exact matches
«The
mice that had the most TRPV4 appeared to have the most pain, but they all had similar evidence of temporomandibular
joint inflammation and bone erosion in the jawbone
as a consequence of the inflammation.»
Control
mice that received healthy cartilage in both flanks showed little damage,
as did
mice that received implants of fibroblasts from patients with osteoarthritis, which does not spread from
joint to
joint.
What's more, the
mice developed symptoms typical of rheumatoid arthritis in humans: Their
joints became inflamed and were filled with immune system chemical messengers, such
as TNF - α, which make the immune system turn on the body.
The recovery of attenuated, non-cultivable B. burgdorferi and the observation of remnants within
joint tissue from antibiotic - treated
mice have generated confusion
as to the role of this persistent pathogen in PTLDS [16 — 19].
In some instances, the flaps can actually use the nutrients in the
joint fluid and grow larger, becoming what are referred to
as «
joint mice.»
Cetyl myristoleate is a newer supplement that seems helpful and was originally isolated
as the underlying reason a strain of white
mice was resistant to
joint stress.
The surgery has two objectives — remove stuff that might be irritating, such
as cartilage flaps,
joint mice and osteophytes (visible ridges of arthritis) and curette the damaged area down to healthy bone so that fibrocartilage will form over the area.
Of course, the presence of loose bony pieces such
as these (they are often called
joint mice) leads to inflammation and pain.
The zigzags and pushed - out curves are retained in the subsequent paintings
as a structural set for some cartoonish imagery — a joke artist's palette and brushes, Mickey
Mouse feet, a
joint smouldering in the palm on a Mickey
Mouse hand, cartoon smoke, bliplike baby shapes.