Sentences with phrase «as keratinocytes»

Ng explains, «The two - step bioprinting strategy involves the fabrication of hierarchical porous collagen - based structures (that closely resembles the skin's dermal region), and deposition of epidermal cells such as keratinocytes and melanocytes at pre-defined positions on top of the biomimetic dermal skin constructs, to create 3D in - vitro pigmented human skin constructs.

For example, earlier research suggested that Neanderthal DNA influenced skin cells known as keratinocytes that help protect the skin from environmental damage such as ultraviolet radiation and germs.

Wei Long Ng explained: «The two - step bioprinting strategy involves the fabrication of hierarchical porous collagen - based structures (that closely resembles the skin's dermal region), and deposition of epidermal cells such as keratinocytes and melanocytes at pre-defined positions on top of the biomimetic dermal skin constructs, to create 3D in - vitro pigmented human skin constructs.

Not exact matches

Used together, these products offer antioxidant protection, gentle controlled exfoliation, interruption of communication between melanocytes and keratinocytes, as well as inhibiting the production of excess melanin.

Between 2009 and 2013, the Veterans Affairs Keratinocyte Carcinoma Chemoprevention Trial randomly assigned 932 veterans who each had at least two prior basal cell carcinomas (BCCs) or SCCs to either receive the 5 - FU cream or a cream just like it but without the active ingredient as an experimental control.

«We culture typical skin cell of the epidermis, such as human keratinocytes, in our dishes to form an artificial epidermis with all of its natural layers,» explained Sibylle Thude, the biologist who led the investigation into the accreditation.

The surgery is known as melanocyte - keratinocyte transplantation or MKTP.

The new findings suggest that Neanderthal genetic variants increase the risk of developing sun - triggered skin lesions known as keratoses, which are caused by abnormal keratinocytes.

Havran, MacLeod and their colleagues also hope to learn further details of the molecular cross-talk between DETCs and keratinocytes, as well as the role of DETCs in protecting against other environmental threats, such as the ultraviolet radiation that causes sunburn and skin cancers.

One potential treatment involves injecting the wound with stem cells, which can change into other cell types, such as skin cells like keratinocytes, to help with the healing process.

It is believed to result from a combination of genetics and environmental factors such as irritants and allergens that drive T lymphocytes to produce factors that cause abnormal changes in keratinocytes, the predominant cell type in the outermost layer of skin, as well as changes in other cells in the underlying dermis.

As a result, new keratinocytes move to the outer layer of skin faster than old skin cells can be sloughed off.

The top four images, from left to right, show Keratinocyte - derived neural crest stem cells turning into neurons as shown by typical neuronal morphology.

In human skin, keratinocytes, the cells found in the outer layer of our skin known as the epidermis, soak up our naturally occurring melanosomes.

Once seeded onto a proper support, these keratinocytes appeared capable of forming a pluristratified epidermis both in vitro and in vivo as xenografts in immunodeficient mice.

Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etc.).

In parallel, the generation of functional melanocytes from pluripotent stem cells, capable of producing melanosomes and transferring them to keratinocytes, will facilitate in vitro analysis of molecular mechanisms underlying melanocytic defects observed in genetic diseases such as neurofibromatosis or albinism.

Preferential induction of apoptotic cell death in melanoma cells as compared with normal keratinocytes using a non-thermal plasma torch.

The role of these molecules in driving disease pathology might vary, with described activities of HVEM signaling promoting T cell expansion or survival, analogous to certain activities of OX40 and 4 - 1BB, and other activities of HVEM or LTβR increasing the function of diverse cells such as stromal cells, dendritic cells, macrophages, eosinophils, epithelial cells and keratinocytes.

Skin substitutes involve different cell composites, such as: fibroblasts, keratinocytes, epithelial cells and / or MSCs transplanted on membranes or with supportive matrix.

For the first set of experiments, first author Trond Aasen, Ph.D., a postdoctoral researcher at the Center of Regenerative Medicine in Barcelona, used viral vectors to slip the genes for the master regulators Oct4, Sox2, as well as Klf4 and c - Myc into keratinocytes cultured from human skin explants.

Melanin produced by melanocytes, is stored within melanosomes and is transferred to keratinocytes by a process known as cytocrinia (the same process by which melanin is transferred, in a normal epidermis, from melanocytes to keratocytes).

Antibiotic - induced inflammatory markers in canine keratinocytes as potential factors in the pathogenesis of skin drug hypersensitivity.