Not exact matches
The custom of families and close friends celebrating the
menarche of a young woman has,
as far
as I know, virtually disappeared.
Detailed information on women's reproductive factors was also collected, such
as age at
menarche, the number of pregnancies, abortions, live births, and the total duration of any breastfeeding for each live birth.
His team,
as well
as independent groups based in the UK, the US and Iceland, uncovered this gene's role by comparing genome - wide scans of thousands of women with their age at
menarche.
Through this effort the mutation was also found to increase the risk of squamous cell carcinoma of the skin and biliary tract cancer
as well
as to cause blood electrolyte imbalance and late onset of
menarche.
Factors examined
as potential confounders or effect modifiers included age (at breast cancer diagnosis for cases, at time of study enrollment for controls), age at first birth, number of children, birth of a son, history of breastfeeding, miscarriage, abortion, oral contraceptive use, smoking status, age at
menarche and number of cell equivalents tested for detection of FMc.
Originated 1970s by Dr. Henry Lemon, who tested estrogen levels in 24 hour urine samples and found that an EQ > 1 strongly correlated with a higher survival rate after breast cancer.24 Further research conducted by Lemon, Heidel, et al., a meta - analysis of published fractional estrogen excretion collected from 2,846 healthy women worldwide aged 15 to 59 years, with a risk of breast cancer varying five-fold, found that an EQ < 1 reflects increased rates of oxidation of estrone or estradiol to 4 - OH catechols (also referred to in the literature
as the 3,4 - catechol estrogen quinones), which have been identified
as the principal proximal human mammary carcinogens after
menarche, while an EQ > 1 reflects conversion to protective 2 - OH estrogen metabolites.2526
They may suffer from abdominal distension and pain, and / or other symptoms such
as: iron - deficiency anemia, chronic fatigue, chronic migraine, peripheral neuropathy (tingling, numbness or pain in hands or feet), unexplained chronic hypertransaminasemia (elevated liver enzymes), reduced bone mass and bone fractures, and vitamin deficiency (folic acid and B12), late
menarche / early menopause and unexplained infertility, dental enamel defects, depression and anxiety, dermatitis herpetiformis (itchy skin rash), etc..
Adding other factors, such
as assay batch, family history of breast cancer, age at
menarche, breastfeeding, physical activity, childhood BMI, smoking, drinking status, and intake of fat and fiber into the multivariable model did not change the result appreciably, but reduced the precision.
Early
menarche remained linked to higher risks of coronary heart disease and deaths from cardiovascular disease and cancer after the researchers accounted for a number of other factors — such
as age, BMI, smoking, exercise habits and education.
Early maturing girls may begin breast development
as early
as third grade and may reach
menarche in fourth or fifth grade.