Sentences with phrase «as microfluidic»

There are alternatives to centrifugation such as microfluidic technology, which has been widely studied for various applications in biological and chemical analysis, point - of - care testing and diagnostics, and clinical analysis.

Chemist John Pojman of Louisiana State University in Baton Rouge adds that such roving droplets «might be useful as a pumping mechanism for microfluidics, converting chemical energy to mechanical motion in small devices,» such as the microfluidic labs - on - a-chip many researchers are developing as diagnostic machines.

«These highly elusive 3 - nanometer structures are too small to be captured with other types of liquid biopsy devices, such as microfluidics, due to shear forces that can potentially destroy them,» he noted.

The approaches combine theoretical studies — including statistical physics of non-equilibrium systems — and a variety of experimental techniques such as optical and electron microscopy, as well as microfluidics and micropatterning, optogenetics, or mechanical micromanipulation using optical or magnetic tweezers.

Not exact matches

Prof. Shen and her unit say that, in the future, nanoplasmonic materials may even be integrated with emerging technologies, such as wireless systems in microfluidic devices, allowing users to take readings remotely and thereby minimizing the risk of contamination.

Just as important, the MFC is readily automated (e.g., Micralyne's Microfluidic Toolkit) and a typical analysis uses nanoliters of reagent.

As bacteria stream through a microfluidic lattice, they synchronize and swim in patterns similar to those of electrons flowing through a magnetic material.

Now scientists at MIT and Cambridge University have identified an unexpected shared pattern in the collective movement of bacteria and electrons: As billions of bacteria stream through a microfluidic lattice, they synchronize and swim in patterns similar to those of electrons orbiting around atomic nuclei in a magnetic material.

Although some of my research focuses on the development of nanoelectronic devices for life science applications (as well as for telecommunications and radio astronomy), most of my research efforts are based on the use of microfluidic chips (MFCs) with molecular biology.

The discovery helps scientists understand the interaction of microswimmers and could help prevent films from forming in microfluidic devices such as labs - on - a-chip.

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended timeAs it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended timeas those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

«Using a new layer - by - layer fabrication process, we created a microfluidic environment in which TEER - measuring electrodes are integral components of the chip architecture and are positioned as close as possible to the tissues grown in one or both of two parallel running channels,» said Olivier Henry, Ph.D., a Wyss Institute Staff Engineer who was the driving force behind the new Organ Chip designs.

There will be demand for really good people in developing new instrumentation, particularly as they move toward nanotechnology and microfluidics platforms.

Many scientists are working to develop microfluidic systems — known as labs - on - a-chip — that can mix small amounts of chemical reagents or biological molecules.

The researchers fashioned a microfluidic chamber 58 millimeters long, 11 millimeters wide, and about 1 millimeter high, as they report today in Science Translational Medicine.

Wardle says the combination of carbon nanotubes and multilayer coatings may help finely tune microfluidic devices to capture extremely small and rare particles, such as certain viruses and proteins.

«Skin - mounted microfluidic devices from the Rogers group allow us, for the first time, to determine sweat and electrolyte loss continuously, as it occurs in the pool during swimming, without any adverse impact on our athletes.

The device is a unique example of microfluidics technology, sometimes called a lab - on - a-chip, that pushes water around in microscopic tubes and reservoirs made from the same cellophanelike plastic as soft contact lenses.

Such micro-structured surfaces have helped design new surfaces that mimic surfaces found in nature, such as self - cleaning surfaces, reduced - drag surfaces, surfaces capable of transporting liquids in microfluidic systems, variants with anti-icing or heat transfer properties, and even surfaces that facilitate oil - water separation.

As part of the HeMiBio (Hepatic Microfluidic Bioreactor) project, researchers at the Fraunhofer Institute for Cell Therapy and Immunology IZI in Potsdam in collaboration with partners at the Hebrew University of Jerusalem have developed a microbioreactor in which liver cells can be kept alive and observed for a period of one month.

«Faster, smaller, more informative: Device can measure the distribution of tiny particles as they flow through a microfluidic channel.»

These results can serve as the foundation of future research on the wide range of possible applications involving microfluidic processes such as water purification and self - powered drug delivery systems.

«WPI brings an outstanding theoretical tool that allows us to understand how microscale objects, such as sperm, interact with their environment; and we are able to design this know - how into real microfluidic devices, clinically validate what we designed, and experimentally improve it into a real - world application.»

The ring functions as a home diagnostic tool that distributes blood into four microfluidic channels.

«Microbiologists have rarely taken into account fluid flow as an ecological parameter, whereas physicists have just recently started to pay attention to microbes,» he says, adding: «The ability to directly watch microbes under the controlled flow conditions afforded by microfluidic technology — which is only about 15 years old — has made all the difference in allowing us to discover and understand this effect of flow on microbes.»

Said Tiffani Lash, Ph.D., director of the NIBIB program in Microfluidic Bioanalytical Systems, «It is exciting to see the continued growth of microfluidic technologies being used as miniaturized diagnostic platforms, particularly in this case for reducing the incidence of preterm labor aMicrofluidic Bioanalytical Systems, «It is exciting to see the continued growth of microfluidic technologies being used as miniaturized diagnostic platforms, particularly in this case for reducing the incidence of preterm labor amicrofluidic technologies being used as miniaturized diagnostic platforms, particularly in this case for reducing the incidence of preterm labor and delivery.

Finally, the enriched P1 peptide is detected as it migrates to a specific position in the microfluidic channel.

The Stanford team is currently developing new applications for EPM actuation in ferro microfluidic systems, as well as optimizing the EPM design.

But with internal light emitters excited from the bottom surface, the external light never comes in contact with the sample, so lensing effects are negated, as is the need for microfluidics.

The researchers view their system as an alternative to the microfluidic devices now commonly used in biological research, in which biological solutions are pumped through microscopic channels connected by mechanical valves.

The researchers showed that they could use alginate as a template for making lab - on - a-chip devices with complex microfluidic channels.

In their article, the teams describe how they used the process to etch patterns of hollow channels like those used to direct the flow of liquids, such as a blood sample, in a microfluidic device, or lab on a chip.

As this preparatory step can be time - consuming, it would be advantageous if microfluidic platforms could come pre-prepared with specific biomolecules sealed inside.

Here, we exploited microfluidics to control the metabolism of liver cells down to a resolution of a few cells, allowing us to create liver tissue that shows the same patterns of toxicity caused by differences in drug metabolism as the liver in your body.»

In tandem with this trend, microfluidic devices using conductive liquid metals have been increasingly employed as wearable pressure and strain sensors.

«A microfluidic device that sorts cells based on their mechanical properties could offer cost and labor advantages over current methods and may provide sufficient enrichment to serve as an alternative or additional approach to antibody - based techniques,» Sulchek says.

«The development of this microfluidic lung model, as well as other organs - on - chip, holds the promise of improving the physiological relevance of cellular models for more accurate prediction of the effects of toxicants and drugs on humans, and for reducing the use of animals in medical and pharmaceutical research,» said Sonia Grego, Ph.D., research scientist at RTI and the project's principal investigator.

«The microfluidic cell cultures reproduced functions of the airway tissues such as mucus secretion and acted as a barrier to molecules,» said Katelyn Sellgren, Ph.D., a postdoctoral research scientist at RTI and first author of the paper.

Sandia's SpinDx device features centrifugal microfluidics, or «lab - on - a-disk» technology, which uses centrifugal forces to manipulate samples and reagents through microfluidic channels implanted on disks that are of the same size as a standard CD or DVD.

PR - PR can be used with liquid - handling robots, microfluidics, and microscopy, as well as for protocol translation into human languages.

DEP can be thought of as a low - frequency analogue of optical tweezers, and it has become a popular technique in the microfluidics and lab - on - a-chip fields because it is so simple.

We work across disciplines and use a variety of techniques including microfluidics, standard microscopies (electron, optical, fluorescence, confocal), spectroscopies (fluorescence, UV, CD), scattering techniques (X-ray, light), protein expression and characterization and cell - free gene expression to investigate the utility of coacervate microdroplets as robust reaction compartments and cellular mimics.

Large - scale and effective studies of biological molecules with a different structural basis such as proteins, nucleic acids, carbohydrates, lipids and numerous metabolites (including e.g. fatty acids, amino acids, purines, pyrimidines or steroids) is currently highly attractive because of the availability of modern instruments and tools for both separation and analysis (2 - D chromatographs, capillary electrophoresis systems, microfluidics, mass spectrometers, powerful NMR spectrometers, DNA / RNA arrays and others).

The primary epithelial cells are expanded as 3D organoids, dissociated, and cultured on a porous membrane within a microfluidic device with human intestinal microvascular endothelium cultured in a parallel microchannel under flow and cyclic deformation.

As outlined below, we used a microfluidic quantitative PCR (qPCR) system to elucidate the gene expression profiles of individual human oocytes and small numbers of cumulus cells using a combination of a large number of samples and targets [12], and then extended our studies via the use of parthenogenesis, in conjunction with gene expression profiling, as a functional assay of cytoplasmic maturation of oocyteAs outlined below, we used a microfluidic quantitative PCR (qPCR) system to elucidate the gene expression profiles of individual human oocytes and small numbers of cumulus cells using a combination of a large number of samples and targets [12], and then extended our studies via the use of parthenogenesis, in conjunction with gene expression profiling, as a functional assay of cytoplasmic maturation of oocyteas a functional assay of cytoplasmic maturation of oocytes.

As a visiting Scientist at the University of Washington, he explored the capabilities of microfluidic culture systems to mimic complex vascular structures.

Organ - on - a-chip technology has seen a vast increase in popularity, as the understanding of utilizing the properties of microfluidics has become more prevalent.

As part of his post-doctoral research at University of Chicago he co-invented the SlipChip - a multiplexed microfluidic platform for high - throughput droplet - based chemistry and biochemistry without pumps or valves.

As Fluidigm IP counsel she supports the mass cytometry and microfluidics technologies.