Sentences with phrase «as molecular markers»

Researchers have been tracking the spread of artemisinin - resistant parasites first by looking for signs in patients, and later by using multiple mutations in the parasite's Kelch13, or K13, gene, as molecular markers for resistance.

«Recognition of human receptors can serve as molecular markers for the pandemic potential of the [isolated strains].»

Taken together, these findings suggest that mutations in the K13 - propeller play an important role in determining artemisinin resistance, act as a molecular marker for artemisinin - resistant parasites, and provide important clues into how resistance is developing in parasite populations in Southeast Asia.

Importantly, these mutations could serve as a molecular marker for large - scale surveillance efforts to contain artemisinin drug resistance in Southeast Asia.

Not exact matches

Published in the peer - reviewed journal Systems Biology in Reproductive Medicine, the study, «Sperm RNA elements as markers of health,» from the lab of Stephen A. Krawetz, Ph.D., the Charlotte B. Failing Professor of Fetal Therapy and Diagnosis in the Wayne State Department of Obstetrics and Gynecology and Center for Molecular Medicine and Genetics, indicates that RNA found in male sperm not only shows promise as a determinant in successful live birth, it may also tell us more about the health of a child as it matures.

As a result, the emphasis in early development is on understanding the molecular underpinnings of disease and developing markers for therapeutic effects.

Global gene expression studies found that the LPA - treated mice shared many similar molecular markers as those found in humans with schizophrenia.

«But these results put us on track to discover molecular signatures in humans that may have the potential to serve as markers for certain types of depression.

They found that women were five times as likely to develop cancer if they had a higher percentage of Ki67, a molecular marker that identifies proliferating cells, in the cells that line the mammary ducts and milk - producing lobules.

The results, published September 2 in Molecular Psychiatry, point toward potential new markers to aid the diagnosis of stress - related disorders, such as anxiety and depression and a promising route to the development of new treatments for these devastating disorders.

Based on anatomy and molecular markers, we propose that it arose by duplication of a neighboring stem cell, which may have enabled finer neuronal control over leg - related behaviors, such as walking and grooming.»

While a range of cellular markers of exhaustion, such as PD - 1 and TIM3, have been characterized and are even the target of cancer immunotherapy drugs, the molecular details of how CD8 T cells switch gears were unclear.

As it turns out, the answer to the question of whether it's possible to predict the usefulness of molecular markers for phylogeographic studies is: it's not always this simple.

This could include measures such as CT scanning, cellular and molecular markers taken from blood samples, sputum and exhaled air and microbiome anaylsis.

Indeed, his team's work already indicates that molecular axis alignments can serve as markers to track molecular movements such the folding of proteins.

Molecular biologists at Stanford University will analyse DNA from blood samples taken from individuals in those families, looking for as many as 300 markers in the DNA that indicate the presence of particular genes.

Most simply, once these genes, or bits of DNA tied to the genes (known as markers), have been identified, molecular breeders can quickly target offspring inheriting the genes for further development, cutting breeding time and improving the crop's «genetic gain,» the generational improvements made to a crop, like increased height, by human selection.

With the advent of more and more sophisticated ways to measure genetic variation and relatedness using molecular markers, such as allozyme polymorphisms and DNA - based markers, not only can individuals be tracked as to their parentage, but changes in allele patterns over time and thus the effects of evolution on populations can be «seen» in the genetic information.

Moreover, combinations of multiple biophysical markers, such as stiffness and size, were about as good as the currently employed molecular marker at classifying stem - like activity.

To develop a model for generating the human colon, scientists first identified SATB2 (special AT - rich sequence - binding protein 2) as a definitive molecular marker for hindgut in frogs, mice and in humans.

Rats born of hypoxic pregnancy with no vitamin C treatment showed increased thickening of the walls of the aorta — up to 170 % above normal — and molecular markers of disease, such as an increase in the heart's heat shock proteins, a signal of cardiac oxidative stress.

The booklet discusses in detail and in simple language agricultural biotechnology as it compares with conventional breeding, the agricultural biotechnology tools used in crops such as tissue culture and micropropagation, molecular breeding and marker - assisted selection, and genetic engineering and GM crops.

The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.

marker (in biomedicine) The presence of some substance that usually can only be present because it signals some disease, pollutant or event (such as the attachment of some stain or molecular flag).

This result gives rise to the possibility of using nanodiamonds, suitably treated to attach themselves to targets that we would like to detect, as MRI markers for molecular imaging applications.

When the molecular imaging research community improves image standardization, there is a greater likelihood of harmonization; i.e., that a specific imaging procedure can be used as a marker across clinical trials; not simply for one clinical trial.

By analyzing the molecular aspects of the extensive immune crosstalk between the fungal pathogen and the human host allows to define novel evasion strategies and defines new molecules which can serve as useful markers to develop new antifungal compounds and vaccine candidates.

In a pioneering case study of genetic distinctness as determined by molecular markers, geneticists are weeding out all but the most distinct Kangal genes.