Known as the phosphatidylserine receptor, or PSR - 1, the molecule can locate and clear out apoptotic cells that are pre-programmed to die as well
as necrotic cells that have been injured and are causing inflammation, said CU - Boulder Professor Ding Xue, who led one study and co-authored the other.
Not exact matches
The 1 - 3 millimeter granuloma also contains fibrous and
necrotic tissue
as well
as a number of other types of immune
cells, making it an extremely complex structure.
When they injected the soil bacterium Clostridium [ck] novyi into the bloodstream of mice with tumours, it spread throughout the
necrotic region, consuming living tumour
cells as well
as dead tissue.
Annexin V - FITC staining was used
as a marker for apoptotic
cells, while PI staining was used
as an indicator of
necrotic cells that had lost membrane integrity.
We believe that the use of DNA binding agents such
as Hoechst can be used to target exposed DNA in other diseases where
necrotic cell death plays a critical role and could be used
as a platform therapy.