Sentences with phrase «as neurodevelopmental»

Attention - deficit / hyperactivity disorder (ADHD) has been viewed as a neurodevelopmental disorder, adversely affecting behavior and school performance, with studies suggesting increased risk for poor adult outcomes.

This rare genetic disorder predisposes patients to increased risks for multiple kinds of cancers as well as neurodevelopmental disorders such as autism.

A key step in this process is to compare symptoms identified by clinicians, such as neurodevelopmental delay or abnormal growth, with an in - house database of all known genes associated with developmental disorders.

So far, Kiehl has assessed more than 5,000 brains and found that psychopaths have functional and structural anomalies that affect emotions, impulse control and cognition, leading him to view psychopathy as a neurodevelopmental disorder — a belief he shares with a number of other researchers and psychologists.

Autism is classified as a neurodevelopmental disorder that manifests itself in markedly abnormal social interaction, communication ability, patterns of interests, and patterns of behavior.

Now autism is identified as a neurodevelopmental disorder and is receiving better coverage.

Not exact matches

It concluded that given the short - term and long - term medical and neurodevelopmental advantages, breastfeeding should be promoted as the norm to new parents.

In the new study, the scientists expressed surprise that the early abnormal growth of brain cells they observed in the fish embryo specifically affected male hormones, potentially indicating why more boys than girls are diagnosed with certain neurodevelopmental disorders such as autism.

In addition to being more highly exposed to As, children appear to be far more sensitive to the potential carcinogenic effects of As49, 50 and have a heightened risk for adverse growth, adverse immune response, and adverse neurodevelopmental outcomes,25,51 - 53 even at relatively low levels of exposure.24, 54 Our results indicate that consumption of rice and rice products increases infants» exposure to As and that regulation could reduce As exposure during this critical phase of development.

This discovery also explains why sensory interferences, including synesthesias and hallucinations, can occur in people suffering from neurodevelopmental disorders such as autism or schizophrenia.

A new multi-institutional study by Japanese researchers shows a potential rare gene mutation that could act as a predictor for two neurodevelopmental disorders, schizophrenia and autism.

Studies of other neurodevelopmental disorders, such as ADHD, have found that black parents tend to underreport their children's ADHD symptoms and interpret ADHD symptoms as disruptive behavior.

The immune system's reach within the CNS is extensive, probably contributing to the initiation and pathogenesis of neurodegenerative diseases, neurodevelopmental disorders such as autism, and mental health disorders such as schizophrenia.

The largest of its kind, the study examined genetic data in 100,000 individuals including 40,000 people with a diagnosis of schizophrenia and also found that some of the genes identified as increasing risk for schizophrenia have previously been associated with other neurodevelopmental disorders, including intellectual disability and autism spectrum disorders.

Dysfunction of these cells, as may occur in disease, is linked to neurodevelopmental disorders and neurodegenerative conditions.

The findings provide clues as to what may be altered in the brain to lead to neurodevelopmental conditions like autism spectrum disorder.

Dr Jessica Agnew - Blais from the IoPPN at King's College London said: «We were very interested by this large «late - onset» ADHD group, as ADHD is generally seen as a childhood - onset neurodevelopmental disorder.

«Family - level stressors, such as witnessing a family member get hurt, created an environment that affected the DNA within the cells of the children,» said lead author Dr. Stacy Drury, director of the Behavioral and Neurodevelopmental Genetics Laboratory at Tulane.

Somatic brain mutations, affecting just pockets of cells, can be harmful, and have been suggested as a possible cause of neurodevelopmental disorders such as autism, epilepsy or intellectual disability (see this review article for further background).

Neonates with severe respiratory problems are at higher risk for long - term complications, such as chronic lung disease and neurodevelopmental problems, throughout infancy and childhood.

Learning more about how synapses change their connections could help scientists better understand neurodevelopmental disorders such as autism, since many of the genetic alterations linked to autism are found in genes that code for synaptic proteins.

The detailed new map of early brain growth in healthy babies could shed light on what goes wrong in neurodevelopmental disorders such as autism, BBC reports.

By mapping the neural processes involved as birds learn mating songs, scientists hope to someday use that knowledge to target specific genes disrupting speech in patients with autism or other neurodevelopmental conditions.

«Given that abnormal synapse formation causes various neurodevelopmental diseases such as autism spectrum disorders and epilepsy, understanding activity - dependent mechanisms of initial synapse formation will be important for developing new therapeutic strategies for these conditions,» explained Dr. Kwon.

Pozzo - Miller says, «There has been a growing realization that neurodevelopmental disorders need not be considered as closed cases simply because the mutations affect early brain development.

Disrupted fetal immune system development, such as that caused by viral infection in the mother, may be a key factor in the later appearance of certain neurodevelopmental disorders.

Though these findings have been obtained in mice, the scientists hypothesize that disrupted coordination between the development of the microglia and that of the brain contributes to an increased risk of such neurodevelopmental disorders as autism and schizophrenia in human beings.

In the United States, the diagnosis of autism spectrum disorders has increased about tenfold over the past two decades, and a 2003 report by the Centers for Disease Control suggests that as many as one in every 166 children is now on the autism spectrum, while another one in six suffers from a neurodevelopmental delay.

According to the National Alliance on Mental Illness: «It is too early to classify schizophrenia as either a neurodevelopmental (impairment of the growth and development of the brain) or a neurodegenerative (progressive loss of structure or function of neurons) disorder, as both seem to occur over the course of the illness.

Working with Bhaduri, who has a background in statistics and bioinformatics, Pollen and Nowakowski began exploring how specific classes of neurons and stem cells in the developing brain contribute to normal brain growth as well as to neurodevelopmental disease, and have begun to build a comprehensive, open - source atlas of gene expression across the developing brain, which they hope will serve as a resource for other scientists.

The new study will focus on four areas of high public health concern: obesity, birth defects and other early outcomes, neurodevelopmental disorders (such as autism and depression), and airway diseases (such as asthma and allergies).

The famous cancer gene BRCA1 may also play a role in neurodevelopmental disorders such as microcephaly (right), which causes small brain size.

Neurodevelopmental disorders such as autism spectrum disorder (ASD) and attention deficit and hyperactivity disorder (ADHD) are on the rise, but its underlying mechanisms are poorly understood.

To demonstrate the effectiveness of his new technique, Zhu already has analyzed approximately 50 mutations of the BRaf gene, mutations that have been linked to tumors and to a neurodevelopmental disorder known as cardio - facio - cutaneous syndrome.

Schizophrenia is generally considered to be a disorder of brain development and it shares many risk factors, both genetic and environmental, with other neurodevelopmental disorders such as autism and intellectual disability.

The results are also important as they suggest that the same sets of genetic risks contribute to different aspects of child development which are characteristic features of neurodevelopmental disorders such as ADHD and autism spectrum disorder.»

All the while Bath has turned the system into a significant research tool on the Brown campus and beyond.In 2012, with funding from the Brown Institute for Brain Science through the Robert J. and Nancy D. Carney Scientific Innovation Fund, Serre and Bath opened their lab up as a «core» called the Rodent Neurodevelopmental Behavioral Testing Facility.

Through the use of stem cell - based organoids researchers are making big strides in the study of neurodevelopmental diseases such as schizophrenia and autism.

Such techniques have the potential to enhance research into the origins of neurodevelopmental and neuropsychiatric disorders such as microcephaly, lissencephaly, autism and schizophrenia, which are thought to affect cell types not found in the mouse models that are often used to study such diseases.

Now researchers at UC San Francisco have taken the first step toward a comprehensive atlas of gene expression in cells across the developing human brain, making available new insights into how specific cells and gene networks contribute to building this most complex of organs, and serving as a resource for researchers around the world to study the interplay between these genetic programs and neurodevelopmental disorders such as autism, intellectual disability and schizophrenia.

The identification of the genetic mechanisms underlying human - specific brain development during evolution will transform our ability to decipher the pathophysiological mechanisms underlying neurodevelopmental disorders affecting humans such as autism or schizophrenia.

Therefore it is hard to make a specific claim about a deficit like anxiety or social interaction as these are features of several psychiatric disorders / neurodevelopmental disorders.

Carter uses methods from cognitive neuroscience including functional magnetic resonance imaging (fMRI) and conducts basic research into the neural mechanisms of cognitive control as well as clinical and translational research in schizophrenia and other neurodevelopmental disorders.

Although genetic deletion of BACE1 results in abolished amyloid pathology in AD model mice, it also results in neurodevelopmental phenotypes such as hypomyelination and synaptic loss, observed in schizophrenia and autism - like phenotype.

These observations have highlighted their value as model organisms to study the etiology of human neurodevelopmental pathologies.

By bringing together a team of cardiologists, neurodevelopmental experts, geneticists, and computational biologists to evaluate these problems together as a unique «syndrome,» they hope to better understand how both problems occur and whether they share similar mechanisms.

Pasca, a neonatology fellow at Stanford, said she «couldn't make peace with» the fact that about three - quarters of premature babies have lifelong neurodevelopmental problems, such as cognitive impairment, cerebral palsy, and autism.

Applications in clinical neuroscience have been particularly useful, and have provided insights into systems - level cortical and subcortical anomalies of functional connectivity in neurodevelopmental disorders such as attention - deficit / hyperactivity disorder (ADHD, Castellanos and Proal, 2012) and schizophrenia (Yu et al., 2012).

Eichler's findings show that the cognitive and neurodevelopmental disabilities that characterize many of the autism spectrum disorders can occur as a result of disruption of many of these hotspots.

Boost Your Child's IQ Naturally The United States has an epidemic of childhood neurodevelopmental disease such as autism, ADHD, Asperger's and mental retardation.