Sentences with phrase «as normal mice»

They were able to show that when mice were inserted with ErythroMer, the artificial blood was able to deliver oxygen to tissues in the same way as normal mice blood.

Another behavior that scientists have observed in Huntington's disease model mice is that they aren't as motivated as normal mice to drink sweet water.

Treated SAMP8 mice could now remember as well as normal mice.

The AS mice took longer to learn this task, but AS mice with reduced levels of the Na / K - ATPase subunit learned the task as fast as normal mice.

Although the mice without Bax started out with the same number of oocytes as normal mice, their ovaries harbored about three times as many oocyte - containing follicles shortly after puberty.

«The J20 / caspase -2 null mice showed the same dendritic spine density and morphology as the normal mice — as opposed to the deficits in the J20 mice,» said co-lead author Julio Pozueta, PhD.

The researchers then placed the mutant mice, as well as normal mice, in a chamber with a metal floor connected to an electrical source.

When these knockout mice were fed a high - fat diet, they gained as much weight as normal mice did, but they managed to remain sensitive to insulin.

In a paper appearing online this week in the early edition of the journal Proceedings of the National Academy of Sciences, University of California, Berkeley, scientists who invented the photoswitch therapy and veterinary colleagues at the School of Veterinary Medicine of the University of Pennsylvania (UPenn) report that blind mice regained the ability to navigate a water maze as well as normal mice.

Mice without FMRP buried marbles obsessively — roughly twice as many marbles as normal mice.

In a study published October 30 in Neuron, the scientists show that mice genetically altered so they don't produce serotonin didn't scratch as much as normal mice when exposed to irritants.

The mice had no apparent physical abnormalities, and they performed learning and motor tasks just as well as normal mice.

So did mice treated with breast milk that were genetically engineered to have guts lacking receptors to EGF, as well as normal mice treated with breast milk depleted of EGF.

That egg might develop as a normal mouse or a knockout.

It functions as a normal mouse but also has multitouch on top.

Not exact matches

Human females can live a normal life span with the disease, as can female mice — the latter species also frequently becomes obese.

In contrast, control mice expressing the normal human prion sequence resisted infection when exposed to same materials — just as humans seem to, even those who consume venison meat.

The behavioral tests used here modeled one dimension of the disease — an inability to experience pleasure from normal activities — but not others, such as stress and anxiety, and probably tap into different brain mechanisms in mice than in humans, he says.

For this study the researchers targeted very specific types of GABA receptors to improve social behaviors with clonazepam, but the team also found that by using a different drug, they could target other GABA receptors and actually reduce the ability to socially interact in normal mice — underscoring that future medications would need to target very specific receptors so as not to diminish the drug's impacts.

Skin grafts of such transgenic mice were rejected by normal C57BL / 10 mice, suggesting that the foreign SLA antigen expressed in the transgenic mice is recognized as a functional transplantation antigen.

To test a nonpermanent approach, the team gave normal female mice the MIS protein as a twice - daily shot.

Next, the researchers introduced into the bladders of the mice either Lactobacillus crispatus, a normal vaginal bacterium; G. vaginalis, which is associated with bacterial vaginosis; or sterile saltwater, as a control.

In healthy mice, normal sperm line up at the center of a part of the testes known as the seminiferous tubule, ready for release (left, arrows).

But unlike the normal mice, those with altered macrophages showed no signs of inflammation, such as changes in insulin production, high levels of immune chemicals, and macrophages in their belly fat.

Older modified male mice metabolised sugar faster than normal mice and females, suggesting that SIRT6 might extend life by protecting against metabolic disorders such as diabetes.

The modified mice had half as much body fat as normal, even when fed a high - fat diet.

Uhl and crew then produced mice that had half the normal number of opiate receptors and as a result, experienced greater discomfort when exposed to a standard mildly painful stimulus.

When they next measured responses in the auditory regions of the brain, a more sensitive test, the mice responded to much quieter sounds: 19 of 25 mice heard sounds quieter than 80 decibels, and a few could heard sounds as soft as 25 - 30 decibels, like normal mice.

These engineered mice see as well as their normal counterparts but they lack ipRGCs.

Four days later, the livers of the non-supressed mice had readjusted to a normal daily rhythm, as revealed by the daily rise and fall of liver - gene expression.

«When we switched off the support cells, the mice licked the air in anticipation of the milk only half as often as normal,» Masmanidis said.

When the researchers examined mice with disrupted IL - 27 function, they found that they were more likely than normal mice likely to die when infected with the virus, and that they died as a consequence of rampant lung inflammation.

By examining the brains of these mice, the researchers observed a substantial decrease in inhibitory CA2 neurons, as compared to a control group of normal, healthy mice — a change remarkably similar to that previously observed in postmortem examinations of people with schizophrenia.

These mice lived just as long as semi-starved lean mice, even though they had at least four times the body fat of normal mice.

In those normal mice, A-beta levels weren't as high as they were in the mutated mice, but the fact that they existed was notable, says study coauthor Weihong Song of the University of British Columbia in Vancouver.

He and colleagues at the University of California, San Francisco, injected the brains of mice with prions they had created in the lab by misfolding normal prion protein, known as PrP.

They found that at 6 months of age, these mice had reduced capillary density and could run only half as far as normal 6 - month - old mice.

The researchers then decided to see what would happen if they boosted sirtuin levels in normal mice as they aged.

Even though the mice appeared normal in many ways, they were unable to tune down their responses to external signals such as noises.

Given this finding, it was likely that mice without gp96 would develop signs of inflammatory bowel disease as they grew, unable to adapt to a normal diet.

Some of the mice were fed a normal diet of «mouse chow,» as Shay calls it, containing 10 percent fat.

After LPS was added, the neutrophils in a mouse lung deficient in CD11b crawled about a third of the distance as the neutrophils in a normal mouse lung.

Normal mice watching chronically itchy mice in other cages increased their own scratching in as little as 5 seconds, whereas mice placed near nonitchy mice didn't show any increase in scratching, researchers report in Science.

Klebsiella pneumoniae is usually a normal resident in the mouth of healthy individuals, but as demonstrated in an experiment on specific pathogen - free mice treated and untreated with the antibiotic ampicillin, they can colonize in the gut and activate TH1 cells when antibiotics disturb the gut microbial balance and weaken tolerance for the colonization of oral bacteria reaching the intestine.

Knocking out a particular gene in muscle lets mice run twice as far as normal; knocking out the same gene in fat cells allows the animals to put on weight without developing type - 2 diabetes.

As a final test to see whether parasites could directly access the brain from the blood, the researchers infected mice with a mixture of normal parasites and mutants that was unable to reproduce, each labeled in different colors.

The team then administered progesterone inhibitors to normal mice and found that the animals behaved much as their knockout counterparts did.

As a result, they have less than half of the fat tissue found in normal, aged mice.

These normal in vivo immune responses in IL -2-deficient mice question the importance of IL - 2 as defined by in vitro studies.

Untreated 3xTg mice displayed impaired learning and memory as expected, but 3xTg mice that were administered PD146176 for 3 months were indistinguishable from normal mice in a memory test.