Sentences with phrase «as novel therapeutic targets»
My short term goals for my postdoc are to identify novel diagnostic and prognostic markers, as well as novel therapeutic targets, leading to several high impact first authored publications.
http://www.lindau-nobel.org/
Floryne Buishand, 30, from the Netherlands, is a postdoctoral researcher at the National Cancer Institute / NIH, Bethesda, USA, studies genomic changes associated with endocrine cancers with the ultimate goal of identifying novel diagnostic and prognostic markers, as well as novel therapeutic targets.
New studies from the Abramson Cancer Center of the University of Pennsylvania are providing fresh clues on potentially effective combinations with CAR T therapy in brain cancer as well as a novel therapeutic target in head and neck cancer, and also providing greater understanding of the mechanisms of resistance in pancreatic cancer.
Not exact matches
The concept of using the immune system as a therapeutic is not new, but our ability to use the immune system to target things we're interested in is novel.
The publication, «Androgens Regulate Prostate Cancer Cell Growth via an AMPK - PGC - 1α - Mediated Metabolic Switch,» featured online in Oncogene, illuminates a known metabolic pathway as a potential novel therapeutic target.
The work published in Cancer Cell complements previous research efforts from the CNIO Melanoma Group, which could lead to the development of novel drugs that selectively target the mechanism of cell autodigestion as a potential therapeutic strategy.
A better understanding of the function of neuromodulators, such as COX - 2 and TIA - 1, may help identify novel therapeutic targets for the treatment of epilepsy.»
«Targeting such pathways, as for instance the Wnt pathway presented in this study, may result in the creation of novel therapeutic approaches for frontotemporal dementia.»
This microRNA — miR -124-3p — is thus a potential therapeutic target for novel drug development, and it can serve as a putative biomarker for MDD pathogenesis.
«Our findings have important translational value since they establish this protein enzyme as a novel and viable therapeutic target with real disease - modifying potential for AD,» Praticò said.
Non-exclusive licenses are available for research and sale of products and services across multiple fields including: research tools, kits, reagents; discovery of novel targets for therapeutic intervention; cell lines for discovery and screening of novel drug candidates; GMP production of healthcare products; production of industrial materials such as enzymes, biofuels and chemicals; and synthetic biology.
AMP T2D focuses on type 2 diabetes genetics, seeking to use and supplement the substantial amount of human genetic data available from people with type 2 diabetes, or at risk of developing it, to identify and validate novel molecules and pathways as targets for therapeutic development.
My Honours project focused on genetically validating the Signal Transducer and Activator of Transcription 3 (STAT3) protein as a therapeutic target by using a novel transgenetic mouse model in which a short hairpin RNA directed against STAT3 can reversibly be induced by the administration of doxycycline.
We are looking at the role of complement proteins in inflammatory diseases such as atherosclerosis, to identify novel therapeutic targets.
These findings establish Frizzled family receptors as disease - relevant receptors for toxin B in the colonic epithelium and provide novel therapeutic targets for treating C. difficile infections.
The goal is to produce a comprehensive «encyclopedia «of gene function, that will help identify causative factors of human diseases as well as novel targets for therapeutic intervention.
Novel therapeutic strategies include inhibitors that target HIF - 1α directly (10) or downstream targets such as VEGF.
This study identified 1,317 distinct genes found to be knocked out in humans; many of these genes (e.g., APOC3, PLA2G7, LPA) are being pursued as therapeutic targets, whereas many others are novel genes of unknown function.
Dalby KN, Tekedereli I, Lopez - Berestein G, et al: Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer.