Through investigation of their mechanism of action we are seeking to advance these agents
as novel treatments for gastrointestinal cancers.
The findings support further development of the drug
as a novel treatment for brain tumors.
Immunotherapy is being investigated
as a novel treatment for cancer.
Dr. Welsbie's laboratory focuses on the development of neuroprotective agents
as a novel treatment strategy for glaucoma.
A new study investigates the great potential of adipose - derived cells
as a novel treatment strategy for the autoimmune neurodegenerative disease Multiple Sclerosis
Deep brain stimulation (DBS) is an invasive neuromodulation modality that has shown early promise
as a novel treatment of Alzheimer's disease (AD).
Shandiz Tehrani, MD, PhD Oregon Health & Science University, Portland, OR Funded by The Alcon Foundation Project: Local Drug Delivery to the Optic Nerve Head
as a Novel Treatment in Experimental Glaucoma
Abstract: Deep brain stimulation (DBS) is an invasive neuromodulation modality that has shown early promise
as a novel treatment of Alzheimer's disease (AD).
Not exact matches
Hence it is wholly consistent of Heidegger to propose
as authentic interpretations of, say, Presocratic philosophy what seem at first to be wholly
novel assertions.6 The seeming voluntarism, not to say willfulness of Heidegger's
treatment of history may not commend his philosophy to our objectivist - empiricist temper, but it is clearly reflected in his analysis in principle of Dasein's authentic having - been - ness and makes a resounding contrast with Mason / Whitehead.
Lampooned mercilessly
as «Professor Bakhlam» in Agnon's
novel Shirah, Uncle Joseph gets tough but sympathetic
treatment in Oz's memoir.
With the approach of Updike's 50th birthday, and with the publication of this his 25th book, it is time to offer an assessment of his work
as a whole: to trace his natively Lutheran vision of life
as cast by God into an indissoluble ambiguity, to examine his
treatment of death and sex
as the two phenomena wherein the human contradiction is most sharply focused, to set this new
novel in relation to the earlier «Rabbit» books, and to determine what is religiously troubling and compelling about Updike's art.
In a collaborative project with several project partners and funded by the European Union and the Deutsche Forschungsgemeinschaft
novel Sclerostin - inhibiting antibodies were generated and analysed for their suitability
as osteoporosis
treatment option.
«This research is highly significant
as it implies that a commercially available drug, amphotericin B, which has never been used before for patients with gliomas, may be a
novel treatment to consider in future trials of patients with this frequently lethal cancer,» says Dr. Rutka.
But these findings point us to new strategies and
novel compounds that can be developed
as treatments that will be more effective for an array of cancer types because they are less susceptible to the emergence of resistance.»
«Our approach is likely to «revive» genome - wide association studies
as a strategy to identify genetic risk factors and to develop
novel treatment options for a wide range of diseases, just
as people had hoped for when the genetic code was deciphered a decade ago.»
«New soft material could reduce complications for women suffering from urinary incontinence: Researchers have developed a
novel implantable material which could reduce the number of debilitating side - effects that occur
as a result of using a material that is too rigid for surgical
treatment of incontinence.»
Researchers at the University of Sheffield have developed a
novel implantable material which could reduce the number of debilitating side - effects that occur
as a result of using a material that is too rigid for surgical
treatment of incontinence.
This approach has been used in other brain disorders, such
as schizophrenia, which has already led to
novel insights and alternative
treatment approaches in that disorder.
Researchers from NUS have developed a
novel handheld device, known
as CLiKX, for the
treatment of a condition called Otitis Media with Effusion, or «glue ear.»
A team of researchers from the National University of Singapore (NUS) has developed a
novel handheld device, known
as CLiKX, for the
treatment of a condition called Otitis Media with Effusion (OME), or «glue ear», which is the leading cause of hearing loss and visits to the doctors among children worldwide.
Scientists have developed a
novel treatment approach for persistent viral infections such
as herpes.
A better understanding of the function of neuromodulators, such
as COX - 2 and TIA - 1, may help identify
novel therapeutic targets for the
treatment of epilepsy.»
The Aberdeen scientists are studying the potential of marine organisms
as a source for new chemical compounds, which could be used to develop
novel treatments for cancer, inflammation, infection and parasitic diseases.
«
As we assess
novel new
treatments and techniques evolve, professional associations will continue to champion quality improvement for all providers in the best interest of patients,» said Dr. Fullerton.
«Diffusion tensor MR tractography may function
as a
novel quantitative tool and marker of
treatment response,» said study coauthor Jennifer W. Uyeda, MD, Brigham and Women's Hospital.
A team of researchers from the National University of Singapore (NUS) has developed a
novel prosthetic heart valve, known
as VeloX, which can be implanted through a small incision for the
treatment of a serious heart valve disorder called mitral regurgitation.
A team of researchers from the National University of Singapore has developed a
novel prosthetic heart valve, known
as VeloX, which can be implanted using a minimally invasive approach for
treatment of a serious heart valve disorder called mitral regurgitation.
The study is investigator led and has therefore focused on clinical need, targeting patients with progressive multiple sclerosis in whom most disability is incurred... The study also reports a predominant effect on neurodegenerative rather than inflammatory outcomes, suggesting a
novel mechanism of action that might be suitable
as combination
treatment with immunomodulatory
treatments... Further phase 3 studies to measure the effect of simvastatin on sustained disability, particularly in patients with non-relapsing secondary progressive and primary progressive multiple sclerosis, are clearly needed, but this trial represents a promising point from which to develop trials of progressive disease.»
«Because we found changes in the brain
as a consequence of binge eating that were predictive of decreased myelination, therapeutically promoting remyelination may represent a
novel treatment avenue for promoting recovery from negative feeding behaviors in eating disorders,» explained corresponding author Camron Bryant, PhD, assistant professor of Pharmacology and Experimental Therapeutics & Psychiatry at BUSM.
Untapped resource Researchers at Scotland's University of Aberdeen Marine Biodiscovery Center (MBC) are studying the potential of deep - sea marine organisms
as a source for new chemical compounds, which could be used to develop
novel treatments for cancer, inflammation, infection and parasitic diseases.
«A drug that blocks heparanase may represent a
novel treatment for long - term inflammation associated with HSV - 1 infection
as well
as other inflammatory disorders of the eye,» he said.
The end result is helping patients with pulmonary disorders breathe easier,
as well
as their surgeons in considering
novel treatment approaches.
The research suggests that butein and other natural compounds that block inflammation in the brain should be vigorously investigated
as novel anti-diabetic
treatments, he says.
Dr Daniel Martin, Senior Lecturer and Honorary Consultant, UCL Division of Surgery and Interventional Science and Director of UCL CASE Medicine, adds: «These exciting results give us a unique insight into the possible mechanism of insulin resistance in diabetes and provide some clues
as to where we should be thinking about focusing further research on
novel treatments for this disease.
This study strongly supports the need to test and identify
novel compounds that target alternative pathologic mechanisms, such
as inflammation and synaptic maladaptation, for individuals who are resistant to currently available
treatment.
In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of
novel grape - derived compounds, dihydrocaffeic acid (DHCA) and malvidin - 3» - O - glucoside (Mal - gluc), which might be developed
as therapeutic agents for the
treatment of depression.
«Potential
novel treatment for influenza discovered: Scientists pursue new therapies
as deadly H7N9 flu spreads in China.»
The finding provides new insight into how diseases, such
as muscular dystrophy, that disconnect brain and body occur,
as it points to
novel treatment targets, said neuroscientist Dr. Lin Mei.
As an initial focus, researchers at Chicago will search for
novel ways to take advantage of steroid hormones and their receptors to detect metastases, define their boundaries and deliver
treatments directly to tumor cells in order to inhibit cell division or promote cell death.
Many of these
novel cancer immunotherapy approaches, which originated from basic science research in CCIR laboratories, are now being explored
as new
treatment modalities in patients, with a significant number advancing through clinical trials towards FDA approval.
«Dr. Meyers» research is a perfect example
as to how fundamental laboratory studies are leading to innovative and
novel therapies for breast cancer
treatment,» says Dr. Raymond Hohl, director of the Penn State Hershey Cancer Institute.
«
As we understand the nature of the interaction between viruses and host immunity, we will be better placed to intervene in this delicately balanced arms race in order to develop
novel treatments and interventions,» Katzourakis noted.
New study have identified the inhibitor of a protein involved in cell protection
as a potential target for
novel Alzheimer's
treatment
To cite a few instances, polymerase chain reaction (PCR), a molecular method developed over three decades ago, has been widely applied in disease diagnosis, disease mechanism deciphering, and prognosis prediction; the elucidation of tyrosine kinase activity in cancer cells has led to the development of
novel drugs for cancer
treatment; and the identification of proteins and genetic molecules by molecular methods
as biomarkers for disease diagnosis and prognosis has been drawing great interest.
«
As a result, a strong preclinical proof - of - concept has already been established for this
novel approach to the
treatment of nicotine addiction that drives the harmful tobacco smoking habit,» Markou said.
We propose that this antibody could be used
as a
novel, putative therapy for the
treatment of AD.
ViaCyte, a private company that has emerged
as a leader in the field of regenerative medicine, is currently focused on developing a
novel cell therapy for the
treatment of diabetes.
Dr. John Lewis's research interests lie in the areas of nanotechnology and imaging
as they relate to the development of
novel treatments for chronic diseases such
as aging and cancer.
Navire Pharma is a new company aimed at developing
novel small - molecule inhibitors of a tyrosine - protein phosphatase called SHP2 (also known
as PTPN11) for genetically - driven and
treatment - resistant cancer.
This finding reveals unexpected roles for the microbiome and innate immune signalling in the pathogenesis of a cerebrovascular disease,
as well
as suggesting
novel strategies for its
treatment.