Sentences with phrase «as nuclear genes»

Further genetic information such as nuclear genes and morphological relationships should reveal genetic similarities and crossbreeding process in future investigations.

Piroska Szabó of the Van Andel Research Institute in Grand Rapids, Michigan, was once excited to think she'd discovered a new gene that expressed only the maternal allele — until she realized that the RNA sequences she was looking at were from a gene that had been misannotated as a nuclear gene, explaining the maternal - only inheritance.

Not exact matches

And the same is going to be true now as public interest shifts from nuclear physics to molecular biology, from the splitting of atoms to the splicing of genes.

For example, nuclear factor - kappa B (NF - kB) is a complex of proteins that acts as a master switch for turning inflammation genes on and for controlling cell death.

Working with cultures of respiratory tract cells, Elias's team found that the gene that codes for il - 6 is inactive unless a protein known as nf - kb (nuclear factor - kappa beta) attaches to the gene.

As subpopulations moved into isolated areas, how did they remain isolated over a long enough time for new species - defining traits to arise in nuclear genes and become enriched by natural selection to permit speciation?

The goal of the NIH program, as described on its website, is «to understand the principles behind the three - dimensional organization of the nucleus in space and time (the fourth dimension), the role nuclear organization plays in gene expression and cellular function, and how changes in the nuclear organization affect normal development as well as various diseases.»

And they put their new genes to work, degrading toxic chemicals, such as chlorobenzene, that are commonly found at nuclear waste sites.

They later showed that RORA, a nuclear hormone receptor that functions as a transcription factor, can potentially regulate the transcription of more than 2,500 genes, including over 400 genes already associated with autism.

The researchers detected some left - behind nuclear genes in supposed ancients, such as Giardia, Trichomonas and some microsporidia.

Originally, however, they were not examining brown fat thermogenesis, but instead were looking for clues to the function of ERRβ, a protein about which little was known at the time, except that it was closely related to ERRα, appeared in brown fat cells, and also worked as a so - called nuclear receptor — a molecular switch for gene activation that can be turned on by small lipophilic molecules or a signaling protein partner.

Much of what they sequenced turned out to be microbial contaminants, as expected, but 6 percent was cave bear nuclear DNA, including bits of 21 genes.

The branch uniting the fungi and animals is well - supported based on a number of molecular phylogenetic datasets, including the nuclear small subunit ribosomal RNA gene (Wainwright et al., 1993; Bruns et al. 1993), unique and shared sequence insertions in proteins such as elongation factor 1α (Baldauf and Palmer, 1993), entire mitochondrial genomes (Lang et al., 2002), and concatenated protein - coding genes (Steenkamp et al., 2006).

However, the authors found no evidence for a role of Setd7 in histone methylation or as a partner of MyoD in MuSCs and instead, they discovered that Setd7 interacted with - catenin and modulated its methylation status to promote nuclear translocation and the transcription of Wnt - responsive myogenic genes.

Not only were selected «test» genes that served as markers turned off after being attached to the inner nuclear membrane, but also nearby «real» genes.

«So we think that these proteins are part of the molecular machinery that is used for positioning genes at the inner nuclear membrane, as well as potentially for repressing them,» he said.

A potential shortcoming of supermatrices that include both mitochondrial and nuclear data is that combined analyses mask genuine cytonuclear dissociation (i.e., mito - nuclear discordance), which occurs when nuclear and mitochondrial genes have different evolutionary histories owing to processes such as introgression of mtDNA, demographic disparities, and sex - biased asymmetries including male - biased dispersal [72]--[75].

A rare, premature aging disease, Hutchinson - Gilford progeria is caused by a single point mutation in the gene encoding lamin A, which forms a protein scaffold on the inner edge of the nucleus that helps maintain chromatin structure and organize nuclear processes such as RNA and DNA synthesis.

Alignments for all of the other nuclear genes, as well as mitochondrial genes, were performed with Se - Al [136].

The same topology is supported by the nuclear gene data sets generated by alternative methods as well as by other inference methods (Supplementary Note 7).

The increased CDK9 levels in the SEC was most likely due to the enhanced transcription of the three SEC genes as revealed by qRT - PCR (Figure 6B), which in turn resulted in elevated levels of these proteins in the nuclear extracts (Figure 6A).

The vitamin A — RXR - alpha complex «dimerizes» with these other nuclear receptors, forming a new complex that acts as a transcription factor to turn on gene expression.

Denzel Washington and Gene Hackman show us how it should be done, as a gung - ho nuclear sub captain meets his match, writes Emily Wilson