Unusually for such a project, the TSRI chemists analyzed the 3D atomic structure of their template compound using X-ray crystallography as well
as nuclear magnetic resonance spectroscopy.
Not exact matches
Although students at this level learn the basics of techniques such
as nuclear magnetic resonance and infrared
spectroscopy in school, «they don't have the advantage of using instruments,» Hewson points out.
To map the minute landscape of molecules, at scales
as tiny
as just tenths of a nanometer, and help decipher their functions, structural biologists have long relied on two tools:
nuclear magnetic resonance, or NMR,
spectroscopy and X-ray crystallography.
He used infrared
spectroscopy to verify the presence of water on precursor lead - oleates, and
nuclear magnetic resonance to show that the lead oleate acted
as a drying agent, grabbing water out of the solvent.
It adapts a technique known
as ligand - based
Nuclear Magnetic Resonance (NMR)
spectroscopy to reveal which amino acids in the protein are involved in binding to the drug.
Our experimental and theoretical analysis draws upon
nuclear magnetic resonance (NMR)
spectroscopy, a variety of microscopy techniques such
as transmission electron microscopy, computation tools such
as the NWChem for high - performance computational chemistry
as well
as supercomputers, and other tools.
The technology brings together the power of
nuclear magnetic resonance spectroscopy, which yields a remarkable peek into molecular interactions, and the ability to re-create the extreme conditions found on the tundra, in the deep ocean, or underground — conditions relevant to some of the biggest questions that scientists at DOE laboratories such
as PNNL ask.
He'd found his way from the University of Utrecht, in the Netherlands, where he'd done his PhD on
Nuclear Magnetic Resonance (NMR)
spectroscopy, to Uppsala, in Sweden, where
as a young post-doc he was learning X-ray crystallography from Alwyn Jones.