Sentences with phrase «as nucleic»

Pine Pollen is also rich in more exotic, albeit vitally important, compounds such as nucleic acids (DNA - repairing fragments) and superoxide dismutase, a powerful antioxidant and cell protectant, among many others.

Over the past decade, healthcare providers have been able to expand screening programs for chlamydia thanks to the development of a highly sensitive method known as nucleic acid amplification testing (NAAT).

Not exact matches

This blockchain manager would «compute a cryptographic hash» of a given «nucleic acid sequence» and «use» it as PoW before transmitting the attendant «new block... to the other nodes in [the] blockchain system.»

According to one of his analogies: just as the sequence of letters on a page is extraneous to the chemistry of ink and paper, so the sequence of nucleic acids in the DNA molecule (which, when translated, determines the shape of an organism and its specific characteristics) is extraneous to the chemical forces operative in the genetic process.

if you disolve a mixture of carbon dioxide, sulther dioxide and ammonia all of which occur naturally in water and then run a high voltahe electric current through it (i.e lightning) amino acids and nucleic acids will spontaneously form and breakdown as the chemicals react.

Nucleic acids are also helping scientists to detect biomarkers, such as Abcam's Fireplex (formerly Firefly) particle technology, which profiles biomarker microRNAs (miRNAs) directly from biofluid samples, without RNA purification.

The exterior of the nanoparticle is coated with nucleic acids that act as targeting agents, drawing the delivery system to the retina and facilitating uptake by RPE cells.

Using a combination of old - fashioned clinical observation and modern biochemical analysis, he has shown that a person's appetite and their eating behavior can be linked to specific genes — and that even a tiny defect such as the absence of a single nucleic acid in a sequence of DNA can lead to runaway weight gain.

These improvements push the boundaries of nucleic - acid detection and fragment sizing, affecting applications such as single - cell nucleic acid analysis, PCR - free preparation of NGS library preparation, bacterial artificial chromosome clone sizing, and exosome analysis.

Magnetic beads have long been used to isolate nucleic acids as well as recombinant proteins.

The technique as proposed would work because nucleic acids like DNA are promiscuous.

The new chimera interferes with HER2 and HER3 signaling and ultimately leads to cancer cell death, as shown in the group's recent publication in Molecular Therapy: Nucleic Acids.

The first application of the Helinx technology, the Intercept Blood Systems, exploits the fact that while blood components such as red blood cells, plasma, and platelets do not contain nucleic acids, viruses and bacteria do.

Nucleic acid and protein sequences, as well as three - dimensional structures of proteins, are frequently the objects of study, but gene expression as well as the simulation of pathways and biochemical networks are attracting more and more attention.

The article in the journal Molecular Therapy — Nucleic Acids titled «As Technologies for Nucleotide Therapeutics Mature, Products Emerge» describes the analysis of more than 60,000 research publications related to oligonucleotide therapies.

And, given the wide applicability of electrochemical detection to many types of biomolecules, the platform «can be readily extended to the detection of other disease markers such as proteins, metabolites, ions, and nucleic acids,» Liu added.

«As long as there are sufficient nucleic acids preserved in the specimen, there is really no limit,» says Alison Devault, a researcher at McMaster University studying ancient cholerAs long as there are sufficient nucleic acids preserved in the specimen, there is really no limit,» says Alison Devault, a researcher at McMaster University studying ancient choleras there are sufficient nucleic acids preserved in the specimen, there is really no limit,» says Alison Devault, a researcher at McMaster University studying ancient cholera.

Now, Wyss Institute researchers led by Church have developed a new suite of such sensors, reported in Nucleic Acids Research journal, that not only increase the number of cellular «switches and levers» that scientists can use for complex genetic re-programming, but also respond to valuable products such as renewable plastics or costly pharmaceuticals and give microbes a voice to report on their own efficiency in making these products.

To see how a size disparity would affect the crystalline order and the system's physical properties, Olvera de la Cruz and postdoctoral fellow Zhenwei Yao devised a model system of soft particles, such as functionalized nanoparticles with grafted chains including nucleic acids or thiols.

It also hints at why proteins were eventually preferred by evolution over nucleic acids as catalysts in biology: proteins offer much more ability to «tune» their «jiggling and wiggling» and their response to chemical reactions.

The find highlights how ancient viruses can more easily be identified by their proteins than their more commonly studied nucleic acids, such as DNA or RNA.

«We had previously learned that messenger RNA, a nucleic acid present in all living cells whose primary role is to act as a messenger carrying instructions from DNA, moves between parasitic plants and their hosts, but we have yet to discover the significance of this exchange.

Led by Dr. Peter Glazer, chair of therapeutic radiology, Dr. Mark Saltzman, chair of biomedical engineering, and Dr. Marie Egan, professor of pediatrics and of cellular and molecular physiology, the collaborative team used synthetic molecules similar to DNA — called peptide nucleic acids, or PNAs — as well as donor DNA, to edit the genetic defect.

Genetic therapies, such as those made from DNA or RNA, face challenges because of the difficulty in delivering the nucleic acid to the right cells.

As published this week in Nucleic Acids Research, they have discovered a mechanism that regulates the expression of alpha - synuclein, a protein linked to Parkinson's disease and multiple system atrophy (MSA).

Intrigued by the ability of certain polymers to mop up DNA and RNA for gene transfer, Sullenger and colleagues tested the idea that these chemical compounds might also be effective targeting such nucleic acids as they arise in cell death.

Nucleic acids and proteins trapped in ancient mummies and still more ancient bones can serve as time capsules of history.

«We've shown that these oviductosomes are carrying critical molecules that include not only proteins, but also nucleic acids such as RNA and also lipids,» DeLeon says.

The origin of life is not the same as the origin of its constituent building blocks, but laboratory studies on the linking of amino acids into molecules resembling proteins and on the linking of nucleotides into molecules resembling nucleic acids are progressing well.

Another idea is to probe the mother's bloodstream for cells and nucleic acids shed by the placenta as a window into the function of the organ.

Bacterial microbes face a never - ending onslaught from viruses and invasive snippets of nucleic acid known as plasmids.

To survive, the microbes deploy an adaptive nucleic acid - based immune system that revolves around a genetic element known as CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats.

Typhoon supports phosphor imaging, 2D difference gel electrophoresis imaging, and RGB and NIR fluorescence, as well as sensitive and accurate quantitation of proteins, nucleic acids, and other biomolecules.

Even a mannequin imprinted with glowing As, Cs, Ts and Gs — representing the four nucleic acid bases that make up DNA — pales in comparison to a giant squid on another floor.

Extracted nucleic acid was amplified using a random PCR method to generate cDNA libraries for Virochip and deep sequencing analyses as previously described [18], [21].

Biochemistry is the study of the structure and function of cellular components, such as proteins, carbohydrates, lipids, nucleic acids, and other biomolecules.

Nitrogen is a key constituent of biological molecules such as amino acids and nucleic acids.

When the researchers added radio - labelled arsenate to the solution to track its distribution, they found that arsenic was present in the cellular fractions containing the bacterium's proteins, lipids and metabolites such as ATP and glucose, as well as in the nucleic acids that made up its DNA and RNA.

In 2007, Rodolphe Barrangou, a former Chairman of the Board of Directors of Caribou Biosciences and current scientific advisor, led the group that characterized CRISPR systems as a form of prokaryotic adaptive immunity that provides a critical line of defense against invading phages, plasmids, and environmental nucleic acids.

«Antisense» compounds are synthesized with nucleotides, the building blocks of nucleic acid, often shown as various combinations of A, U, G and C.

In the 11 years before joining the CNAG he worked at the Centre National de Génotypage of the Commissariat à l'Energie Atomique in Evry, France, first as Head of Technology Development and later as Associate Director under Prof. Mark Lathrop.His research interests are high - throughput nucleic acid analysis, sequencing, SNP genotyping, genomics, genetics, nucleic acid and protein analysis methods (molecular biological techniques and chemical modification), implementation of methods, automation and analysis.

Overgrown cultures stimulate quiescence, the resting phase of the cell cycle; quiescent cells do not take up nucleic acid or express transgenes as well as actively dividing cells resulting in lower lentiviral titers.

Our cells depend on thousands of proteins and nucleic acids that function as tiny machines: molecules that build, fold, cut, destroy, and transport all of the molecules essential for life.

It was suspected, but not known for certain, that fly as well as mouse Zucchini proteins were nucleases — enzymes that specialize in cleaving bonds between the nucleotide subunits of nucleic acids (DNA and RNA).

Nucleic Acid - Modified Nanostructures as Programmable Atom Equivalents: Forging a New «Table of Elements by Robert J. Macfarlane, Matthew N. O'Brien, Dr. Sarah Hurst Petrosko, and Prof. Chad A. Mirkin.

Jörg brings over 17 years» experience in drug discovery and development across key areas such as oncology, infectious diseases, vaccinology, and autoimmunity, with a focus on peptide and nucleic acid - based therapeutics.

Nucleic acids are not only key molecules for the storage, replication and transcription of genetic information, but also serve as enzymes or regulators of a number of cell processes.

Large - scale and effective studies of biological molecules with a different structural basis such as proteins, nucleic acids, carbohydrates, lipids and numerous metabolites (including e.g. fatty acids, amino acids, purines, pyrimidines or steroids) is currently highly attractive because of the availability of modern instruments and tools for both separation and analysis (2 - D chromatographs, capillary electrophoresis systems, microfluidics, mass spectrometers, powerful NMR spectrometers, DNA / RNA arrays and others).

Manuscripts describing BioGPS have been published in the database issues of Nucleic Acid Research in 2016 and 2013, as well as in Genome Biology.

The Unit's scientific mission covers the design, synthesis, molecular modeling, as well as biophysical, biochemical and cellular studies of small - molecule probes and drug candidates targeting nucleic acids or proteins involved in cancer.