The Hippo pathway not only defines final tissue size by controlling developmental growth, but is also key to specifying stem cell identity and proliferation, to regeneration and tissue repair, as well
as numerous cell fate decisions.
Not exact matches
As we read this history, the furor over stem
cells was fueled by
numerous factors: the near - universal human desire for magic; patients» desperation in the face of illness and their hope for cures; the belief that biology can now do anything; the reluctance of scientists to accept any limits (particularly moral limits) on their research; the impact of big money from biotech stocks, patents, and federal funding; the willingness of America's elite class to use every means possible to discredit religion in general; and the need to protect the unlimited abortion license by accepting no protections of unborn human life.
Hartshorne focuses on atoms and
cells as clear instances of individuals.26 He notes that «all individuals apparent to the senses are compounded of
numerous much smaller individuals.
It's rich in protein, sugar, vitamins and minerals, plus
numerous bioactive components — such
as hormones, growth factors, enzymes and live
cells — to support your baby's healthy growth and development.7
Numerous smaller nonprofits, such
as the Robert Packard Center for ALS Research and the Australian Stem
Cell Centre, to name two, have a specific biomedical focus.
To answer this question, the researchers created
numerous premature stop signs, known
as nonsense mutations, in test genes in human and yeast
cells.
Escherichia coli and many other bacteria produce cellulose
as a key component of the extracellular matrix that coats the
cells to form a biofilm, a complex multicellular community consisting of
numerous bacteria, exopolysaccharides (like cellulose), protein fibers, and DNA (4 — 6).
These
cells can secrete
numerous bioactive molecules such
as chemokines, which can attract other
cells.
They found
numerous genes activated in the XYL regulon - controlled yeast that upregulated pathways involved in growth, such
as cell wall maintenance,
cell division, mitochondrial biogenesis and adenosine triphosphate (ATP) production.
Indeed, after Siddle added a squirt of interferon - gamma — a chemical messenger that activates
numerous genes involved in producing MHC antigens — to
cells cultured from devil tumors, the MHC genes functioned normally again, and the tumor
cells» identity cards showed up, plain
as day.
But exactly how the immune system works remains, in many ways, a mystery,
as there are
numerous cell types whose functions and interactions with our immune systems have not been well understood.
In earlier work, these investigators showed —
as numerous others had done — that the messenger molecule, cyclic - di - GMP (c - di - GMP) promotes biofilm formation when such surfaces are present, said principal investigator Vincent T. Lee, Associate Professor, Department of
Cell Biology and Molecular Genetics, University of Maryland, College Park.
UV damage to the skin causes the immune system to recruit
numerous signalling molecules — such
as chemokines — and immune
cells to fight infection.
As an example of the aqueous zinc battery's power and safety, Fei Wang, a jointly appointed postdoctoral associate at UMD's Clark School and ARL, and first author of the paper, cites the
numerous battery fire incidents in
cell phones, laptops and electric cars highlighted in recent media coverage.
Commensal bacteria in the lower intestine of mammals are 10 times
as numerous as the body's
cells.
Rather than artificially triggering cancer by engineering genetic mutations, this model more closely mimics human liver cancer in that tumors develop
as a natural consequence of non-alcoholic steatohepatitis (NASH), a chronic metabolic disorder that causes liver damage, fibrosis and
numerous cell mutations.
GFP has been utilized in
numerous studies
as a marker protein that can track chemical reactions within living
cells, along with various other uses.
As recently as this past May 17, Time magazine reported that despite numerous studies finding no connection between cell phones and cancer, «a growing band of scientists are skeptical, suggesting that the evidence that does exist is enough to raise a warning for consumers — before mass harm is done.&raqu
As recently
as this past May 17, Time magazine reported that despite numerous studies finding no connection between cell phones and cancer, «a growing band of scientists are skeptical, suggesting that the evidence that does exist is enough to raise a warning for consumers — before mass harm is done.&raqu
as this past May 17, Time magazine reported that despite
numerous studies finding no connection between
cell phones and cancer, «a growing band of scientists are skeptical, suggesting that the evidence that does exist is enough to raise a warning for consumers — before mass harm is done.»
A typical brain contains 100 billion
cells — almost
as numerous as the stars in the Milky Way galaxy.
Results of the investigation have
numerous uses in the field of hydrogen fuel
cell vehicles
as well
as the chemical industry,
as this new method is capable of generating hydrogen from methane gas and electricity in just one step and with near - zero energy loss.
The researchers counted the numbers of a particular type of immune
cell, known
as microglia, in the samples and found that these were more
numerous in the brains with Alzheimer's disease.
In cancer, a state marked by increased protein translation and biomass expansion, HSF1 is activated and binds to
numerous genes throughout the genome,
as seen in the heat map of HSF1 ChIP - Seq read density in M0 - 91acute myeloid leukemia
cells (DMSO, far left).
A panel of experts tackles the Alpha Stem
Cell Clinic, a model introduced in the debut issue of STEM
CELLS Translational Medicine, and the challenges in steering this concept around
numerous hurdles
as it moves from the bench to the bedside.
* Contains practical, hands - on information for tissue engineers and students * Provides comprehensive protocols covering
numerous topics, including polymer synthesis,
cell culture, encapsulation, bioreactors, therapeutics, and the creation of tissues and organs * Includes contributions by leaders in the latest areas of research, such
as stem
cells and fetal tissue engineering
Numerous studies have demonstrated activity of these agents against a wide variety of cancers, especially cancer stem
cell - like subpopulations, by a host of different mechanisms which comprise inhibition of signaling pathways, of mitochondrial respiration,
as well
as of cellular stress responses and others.
Activated ERK1 / 2 modulates the functions of several transcription factors, protein kinases, protein phosphatases, cytoskeletal proteins, signaling molecules, apoptosis - related proteins,
as well
as other types of proteins [32], while activated AKT modulates the function of
numerous substrates involved in the regulation of
cell survival,
cell cycle progression and cellular growth [33, 34], whereas JNK acts
as pro-apoptotic
as well
as anti-apoptotic depending on the conditions [35].
PromoKine offers a wide range of well proven products for
cell biology research such
as kits and reagents for
cell analysis, apoptosis research,
cell transfection, fluorescent labeling, gene cloning & expression, mycoplasma detection and elimination
as well
as numerous antibodies, ELISAs, cytokines and growth factors.
Due to its
cell killing effect, radiation therapy is widely used
as a primary source of treatment for
numerous types of cancers.
Specifically, the fluid - filled spaces, known
as ventricles, in the DISC1 - mutant mini-brains were more
numerous and smaller than in controls, meaning that while the expected
cells are present in the DISC1 - mutant, they are not in their expected locations.
My research focuses on the evolution, physiology and biochemistry of alpha crystallins, a group of small heat shock proteins that protect
cells against stress and are implicated in
numerous diseases such
as lens cataracts, Parkinsons, Alzheimers and cancer.
Numerous biochemical and structural changes occur throughout the
cell as the microtubule - based spindle assembles and attaches to the condensed chromosomes, segregates them, and signals to the
cell cortex to induce cleavage into two daughter
cells through an actin - based contraction.
For example, by using histone deacetylase (HDAC) inhibitors, which, by remodeling chromatin structure, are thought to promote gene expression broadly, including for SMN2,
numerous groups showed that they could increase SMN protein levels — both truncated and full - length — in mouse models of SMA
as well
as in patient - derived
cell lines.
However, despite
numerous papers being published demonstrating bulk memory B
cell culture, we could find no literature on optimised conditions for the study of memory B
cell subsets, such
as IgM
+ memory B
cells.
Morgridge computational biologist John Steill, another co-author of the KinderMining study, is using the KinderMiner tool to improve gene marker lists, which have
numerous uses such
as classifying
cells or samples by
cell type and identifying samples that may produce tumors.
There are
numerous, diverse mechanisms that allow a low frequency of gene movement between species, such
as accidental fusion of
cells between different species, or the injection of DNA by bacteria into plant
cells.
Furthermore, saturated fat has been shown to have
numerous positive effects on health, such
as improving liver health by encouraging the liver
cells to get rid of their fat
cells, improving the immune system's response by helping white blood
cells to recognize and destroy invaders more effectively, enabling the absorption of fat - soluble vitamins by acting
as their carriers,
as well
as improving hormonal activity by providing the building blocks for a variety of hormones that are essential to human health.
For example, the bone marrow of patients with anorexia nervosa is often populated with
numerous fat
cells as their body goes into overdrive trying to replace lost fat.
This type of drugs was used for many decades, since skeletal muscle will respond to the exact same meds by increasing the production of heat and
numerous processes within the
cells, a type known
as thermogenic weight - loss meds.
Growth hormone furthermore operates in a roundabout way by encouraging liver
cells to produce and discharge polypeptide molecules referred to
as somatomedins, of which, the most effective and extensively researched for its
numerous health, anti aging and bodybuilding benefits is insulin - like growth factor - 1 (IGF - 1).
Naringin and naringenin possess
numerous health properties such
as antioxidant, anti-inflammatory, and anti-apoptotic (stopping self - destruction of a
cell) activities [6].
Natural vital energy comes primarily from a healthy kidney / adrenal system,
as well
as from cellular mitochondria — the tiny «engines» within
cells that power up
numerous vital functions in the body.
Magnesium has
numerous roles in the body, such
as cell metabolism, DNA and RNA synthesis,
cell growth and reproduction.
* OptiZinc ®, a patented form of zinc, is a trace mineral required for
numerous vital
cell functions, including growth and development
as well
as sexual health.
Mice and human volunteers who underwent cycles of the Fasting Mimicking Diet had decreased numbers of myeloid
cells, the inflammatory immune
cells that become more
numerous as we age, and increased numbers of cytotoxic T
cells, which protect the body against viruses and cancer.
«Given the
numerous health benefits, its participation in important intracellular biochemical pathways, normal physiological presence in our
cells,» and tissues, and blood, and «the levels of which fluctuate with intake, epidemiologic [al] correlates of phytate deficiency with disease and reversal of those conditions [with] adequate intake, and safety — all strongly suggest for [phytate's] inclusion
as an essential nutrient,... perhaps a vitamin.
/ consuming Animal proteins cause
numerous proteins
as it is not designed for us / may be designed to grow that animal at a rate much faster than we are designed for / and also feeds the growth of Cancer
cells / damages the Endothelial
cells / ala Dr. Esselstyn and others.
Chlorella is a microscopic single -
cell freshwater algae which has been found in
numerous studies to be an amazing health promoting superfood used to treat some of the most deadly diseases, such
as cancer, Alzheimer's, and AIDS.
While her new boyfriend's love of baseball is obvious to Lindsey by the d0xC8cor in his apartment and the
numerous jerseys hanging in his closet, it's impossible for her to imagine the depth of his enthusiasm, just
as it's hard for him to understand her dogged dependence on
cell phones and pagers.
The ereader market served
as a nice proof of concept for Neonode and now they have over 50 design wins in
numerous markets from
cell phones to automobiles and printers.
Numerous college grads and students have financial responsibilities such
as rent, health insurance, auto insurance,
cell phone plans and loans thrust upon them.