Sentences with phrase «as oligomers»

This devastating form of dementia is characterized by the accumulation of beta - protein clusters in the brain known as oligomers.
Consistent with this, AFF 1 immunotherapy reduced the accumulation of AS neuropathology in neuronal bodies and neuropil at the cardinal sites for this LBD model (neocortex and hippocampus), and reduced the levels of AS dimers as well as oligomers in brain homogenates, while having no significant effect on monomeric AS.
Summary: Many of the steps are known in using glyoxal with hydrogen peroxide to form dicarboxylic acids and chains of hydrocarbons, known as oligomers.
While these compounds did not reduce the amount of protein aggregates, they were found to reduce the protein's toxicity and to increase the stability of amyloid fibrils — a finding that lends further evidence to the theory that smaller assemblies of amyloid - beta known as oligomers, and not the fibrils themselves, are the toxic agents responsible for Alzheimer's symptoms.
A purified yeast Sec61 complex bound to monomeric yeast ribosomes as an oligomer in a saturable fashion.

Not exact matches

And that sequence can form long chains called oligomers as well as fibers called fibrils.
These oligomers are also the starting materials for troubling atmospheric aerosols, known as secondary organic aerosols.
Amyloid - β 42 (Aβ42) has a strong ability to oligomerize to form diffusible oligomers as well as larger polymers called fibrils that form insoluble amyloid plaques, a major hallmark of AD.
Last but not least, EP1LOGUE features a proprietary vasodilating and nitric oxide - boosting formulation of gallate - enhanced oligomers derived from grape seeds and marketed as 10x more powerful than the classic citrulline.
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